DAMI人巨核细胞白血病细胞

价 格:¥1800

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-1046

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameDami
SynonymsDAMI
AccessionBTCC-1046
Resource Identification InitiativeTo cite this cell line use: Dami (BTCC-1046)
CommentsGroup: Patented cell line.
Problematic cell line: Contaminated. Shown to be a HEL derivative (PubMed=9166871; PubMed=9326259; PubMed=9447816; PubMed=10508494; PubMed=12592342; PubMed=20143388). Originally thought to originate from the peripheral blood of a 57 year old male patient with megakaryoblastic leukemia.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00116.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9792.
Population: Caucasian.
Doubling time: 24-30 hours (Patent=US5128245).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 6192; JAK2; Simple; p.Val617Phe (c.1849G>T); ClinVar=VCV000014662; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Met133Lys (c.398T>A); ClinVar=VCV002430159; Zygosity=Homozygous (from parent cell line).
DiseaseErythroleukemia (NCIt: C7152)
Acute erythroid leukemia (ORDO: Orphanet_318)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
HierarchyParent: CVCL_0001 (HEL)
Sex of cellMale
Age at sampling30Y
CategoryCancer cell line
STR profileSource(s): ATCC; CCRID

Markers:
AmelogeninX (CCRID)
X,Y (ATCC)
CSF1PO10
D2S133818,19
D3S135815
D5S81811
D7S8207
D8S117913,15
D13S3179,11
D16S53911
D18S5112,16
D19S43311,13
D21S1129,31.2
FGA22,23
TH017
TPOX11
vWA14,17

Run an STR similarity search on this cell line
Web pageshttps://www.atcc.org/en/support/technical-support/faqs/dami-atcc-crl-9792
https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

PubMed=3196874; DOI=10.1182/blood.V72.6.1968.1968
Greenberg S.M., Rosenthal D.S., Greeley T.A., Tantravahi R., Handin R.I.
Characterization of a new megakaryocytic cell line: the Dami cell.
Blood 72:1968-1977(1988)

Patent=US5128245
Greenberg S.M., Handin R.I.
Establishment, characterization and differentiation of a new megakaryocytic cell line, the Dami cells.
Patent number US5128245, 07-Jul-1992

PubMed=9166871; DOI=10.1182/blood.V89.11.4238
Handin R.I.
DAMI cell line.
Blood 89:4238-4238(1997)

PubMed=9326259; DOI=10.1182/blood.V90.7.2850
MacLeod R.A.F., Dirks W.G., Drexler H.G.
Early contamination of the Dami cell line by HEL.
Blood 90:2850-2851(1997)

PubMed=9447816; DOI=10.1038/sj.leu.2400868
MacLeod R.A.F., Dirks W.G., Reid Y.A., Hay R.J., Drexler H.G.
Identity of original and late passage Dami megakaryocytes with HEL erythroleukemia cells shown by combined cytogenetics and DNA fingerprinting.
Leukemia 11:2032-2038(1997)

PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::aid-ijc19>3.0.CO;2-2
MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H., Drexler H.G.
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999)

PubMed=11021758; DOI=10.1038/sj.leu.2401891
Majka M., Rozmyslowicz T., Honczarenko M., Ratajczak J., Wasik M.A., Gaulton G.N., Ratajczak M.Z.
Biological significance of the expression of HIV-related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines.
Leukemia 14:1821-1832(2000)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line databases/resourcesLonza; 1426
Anatomy/cell type resourcesBTO; BTO:0001550
Biological sample resourcesBioSample; SAMN03151657
Cell line collections (Providers)KCB; KCB 200782YJ
Encyclopedic resourcesWikidata; Q54828561
Polymorphism and mutation databasesCosmic; 1191696

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