HepG2人肝癌细胞

价 格:¥1800

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-1067

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameHep-G2
SynonymsHEP-G2; Hep G2; HEP G2; HepG2; HEPG2
AccessionBTCC-1067
Resource Identification InitiativeTo cite this cell line use: Hep-G2 (BTCC-1067)
CommentsGroup: Patented cell line.
Problematic cell line: Misclassified. Originally thought to be a hepatocellular carcinoma cell line but shown to be from an hepatoblastoma (PubMed=19751877).
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: ENCODE project common cell types; tier 1.
Part of: JFCR45 cancer cell line panel.
Part of: Liver Cancer Model Repository (LIMORE).
Part of: MD Anderson Cell Lines Project.
Part of: TCGA-110-CL cell line panel.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); HB-8065.
Population: Caucasian.
Doubling time: 25.65 hours (PubMed=31378681); ~50-60 hours (DSMZ=ACC-180).
Omics: CTCF ChIP-seq epigenome analysis.
Omics: H3K27ac ChIP-seq epigenome analysis.
Omics: H3K27me3 ChIP-seq epigenome analysis.
Omics: H3K36me3 ChIP-seq epigenome analysis.
Omics: H3K4me1 ChIP-seq epigenome analysis.
Omics: H3K4me2 ChIP-seq epigenome analysis.
Omics: H3K4me3 ChIP-seq epigenome analysis.
Omics: H3K79me2 ChIP-seq epigenome analysis.
Omics: H3K9ac ChIP-seq epigenome analysis.
Omics: H3K9me3 ChIP-seq epigenome analysis.
Omics: H4K20me1 ChIP-seq epigenome analysis.
Omics: Deep antibody staining analysis.
Omics: Deep exome analysis.
Omics: Deep phosphoproteome analysis.
Omics: Deep proteome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: Genome sequenced.
Omics: Metabolome analysis.
Omics: miRNA expression profiling.
Omics: Protein expression by reverse-phase protein arrays.
Omics: Secretome proteome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Omics: Virome analysis using proteomics.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (PubMed=8389256; PubMed=12068308; DepMap).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=31068700).
HLA typingSource: PubMed=25960936
Class I
HLA-AA*02:01,24:02
HLA-BB*35:14,51:01
HLA-CC*04:01,16:02

Source: PubMed=26589293
Class I
HLA-AA*02:19,24:02
HLA-BB*35:14,51:08
HLA-CC*04:01,16:02
Class II
HLA-DQDQB1*06:04,06:04

Source: PubMed=9178645
Class I
HLA-AA*02:01,24:02
HLA-BB*35,51:01
HLA-CC*04:01,16:02
Class II
HLA-DQDQA1*01:02

DQB1*05:02,06:04
HLA-DRDRB1*13:02,16:02
Genome ancestrySource: PubMed=30894373

Origin% genome


African2.83
Native American20.88
East Asian, North4.48
East Asian, South0
South Asian0
European, North22.82
European, South48.99
DiseaseHepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
HierarchyChildren:



CVCL_B0ZH (Abcam Hep-G2 ACE2 KO)CVCL_B7V5 (Abcam Hep-G2 APOE KO)CVCL_B0ZI (Abcam Hep-G2 ARRB2 KO)
CVCL_B7V6 (Abcam Hep-G2 ARG1 KO)CVCL_B0ZJ (Abcam Hep-G2 B2M KO)CVCL_B0ZK (Abcam Hep-G2 CD63 KO)
CVCL_B0ZL (Abcam Hep-G2 CTNNB1 KO)CVCL_B0ZM (Abcam Hep-G2 LRP6 KO)CVCL_B0ZN (Abcam Hep-G2 MTOR KO)
CVCL_B0ZP (Abcam Hep-G2 NF2 KO)CVCL_B0ZQ (Abcam Hep-G2 NFKB2 KO)CVCL_B0ZR (Abcam Hep-G2 SLC2A1 KO)
CVCL_B7V7 (Abcam Hep-G2 SLC7A11 KO)CVCL_B0ZS (Abcam Hep-G2 TFEB KO)CVCL_KS12 (CellSensor ARE-bla Hep G2)
CVCL_UK01 (DPX2)CVCL_1T06 (H7D7A)CVCL_1T07 (H7D7B)
CVCL_1T08 (H7D7C)CVCL_1T09 (H7D7D)CVCL_Z631 (HC-04)
CVCL_A2HD (Hep G2-C34)CVCL_A2HE (Hep G2-C37)CVCL_A2HF (Hep G2-E43)
CVCL_A2HG (Hep G2-E47)CVCL_A2HB (Hep G2-MV2E1-9)CVCL_A2HC (Hep G2-MV-5)
CVCL_HA60 (HEP G2ins)CVCL_VA32 (Hep-G2 A-1)CVCL_VA33 (Hep-G2 B-1)
CVCL_VA34 (Hep-G2 C-1)CVCL_S027 (Hep-G2 SimpleCell O-GalNAc)CVCL_A5CQ (Hep-G2 VA-13)
CVCL_A5CR (Hep-G2 VA-28)CVCL_A5CS (Hep-G2 VI-7)CVCL_C3G9 (Hep-G2-THRA)
CVCL_C3GA (Hep-G2-THRA MUT p.I116N;A225T;M388I)CVCL_C3GB (Hep-G2-THRA MUT p.K74E;A264V)CVCL_C3GC (Hep-G2-THRB)
CVCL_C3GD (Hep-G2-THRB MUT p.K113N;T329P)CVCL_C3GE (Hep-G2-THRB MUT p.K155E;K411E)CVCL_3701 (Hep-G2/2.2.1)
CVCL_L855 (Hep-G2/2.2.15)CVCL_EQ66 (Hep-G2/BGAL)CVCL_1098 (Hep-G2/C3A)
CVCL_EQ63 (Hep-G2/PGC-1alpha 2x9 mutant)CVCL_EQ64 (Hep-G2/PGC-1alpha L2L3 mutant)CVCL_EQ65 (Hep-G2/PGC-1alpha wt)
CVCL_AS98 (Hep-G2/SF)CVCL_M177 (HepAD38)CVCL_DE22 (HepAD43)
CVCL_DE23 (HepAD79)CVCL_DF32 (HepBHAe82)CVCL_B5VV (Hepc/1A1.4)
CVCL_B5VW (Hepc/1A2.9)CVCL_B5VX (Hepc/2A6L.14)CVCL_B5VY (Hepc/2B6.68)
CVCL_B5VZ (Hepc/2C19.12)CVCL_B5W0 (Hepc/2C8.46)CVCL_B5W1 (Hepc/2C9.1)
CVCL_B5W2 (Hepc/2D6.39)CVCL_B5W3 (Hepc/2E1.3-8)CVCL_B5W4 (Hepc/3A4.2-30)
CVCL_M178 (HepDE19)CVCL_M179 (HepDES19)CVCL_C0V3 (HepG2 AhR-CYP1A1 clone 10)
CVCL_C0V1 (HepG2 AhR-CYP1A1 clone 4)CVCL_C0V2 (HepG2 AhR-CYP1A1 clone 9)CVCL_C0V6 (HepG2 CAR-CYP2B6 clone 10)
CVCL_C0V4 (HepG2 CAR-CYP2B6 clone 6)CVCL_C0V5 (HepG2 CAR-CYP2B6 clone 7)CVCL_IX10 (HepG2 CYP3A4G/7R clone 87)
CVCL_W371 (HepG2 hALR)CVCL_C0V7 (HepG2 PXR-CYP3A4 clone 1)CVCL_C0V8 (HepG2 PXR-CYP3A4 clone 3)
CVCL_C0V9 (HepG2 PXR-CYP3A4 clone 8)CVCL_KU36 (HepG2 Tet-Off Advanced)CVCL_V331 (HepG2 Tet-On)
CVCL_KT01 (HepG2 Tet-On Advanced)CVCL_A5AW (HepG2.105)CVCL_A5AX (HepG2.117)
CVCL_B0UH (HepG2.A64)CVCL_A8FS (HepG2-8960-R)CVCL_XI50 (HepG2-CAR)
CVCL_C5RN (HepG2-CD81)CVCL_XI69 (HepG2-CYP2B6-hCAR)CVCL_A2HH (HepG2-CYP2E1)
CVCL_A9JD (HepG2-CYP3A29)CVCL_9874 (HepG2-DM2)CVCL_A8BS (HepG2-Dual)
CVCL_H214 (HepG2-GS)CVCL_8560 (HepG2-GS-CYP3A4)CVCL_JY40 (HepG2-hNTCP)
CVCL_JG47 (HepG2-Luc)CVCL_5I95 (HepG2-luc2)CVCL_XD61 (HepG2-Luc2-tdT)
CVCL_A8BT (HepG2-Lucia AhR)CVCL_A8IF (HepG2-N10)CVCL_A7DQ (HepG2-NIAS)
CVCL_A8FT (HepG2-R)CVCL_5I98 (HepG2-Red-FLuc)CVCL_XB55 (HepG2-RHBV)
CVCL_JY38 (HepG2-rNTCP-eGFP)CVCL_9873 (HepG2-SM1)CVCL_9872 (HepG2-WT10)
CVCL_M187 (HepG2/Adm)CVCL_C5RP (HepG2/CD81++)CVCL_M186 (HepG2/mdr1)
CVCL_B0UI (HepG2/TC155)CVCL_4W42 (HepG2S1)CVCL_4W43 (HepG2S2)
CVCL_4W44 (HepG2S3)CVCL_HE77 (HepG2T14)CVCL_Y479 (HepG3)
CVCL_DF33 (HepHA-HBe4)CVCL_RW48 (HepJ5)CVCL_DC29 (HG2L1.1c3)
CVCL_DC30 (HG2L6.1c1)CVCL_DC31 (HG2L6.1c3)CVCL_DC32 (HG2L7.5c1)
CVCL_6G77 (HPLA-A3)CVCL_YJ82 (LINTERNA HEP-G2)CVCL_JA65 (NtG20.i7)
CVCL_W369 (PSC-THP1-EPEP)CVCL_W370 (PSC-THP1-HEP)CVCL_C0NN (PZ-TR)
CVCL_D636 (RzM6)CVCL_0578 (WGA)
Sex of cellMale
Age at sampling15Y
CategoryCancer cell line
STR profileSource(s): AddexBio; ATCC; CCRID; CLS; DSMZ; ECACC; Genomics_Center_BCF_Technion; JCRB; KCLB; PubMed=11416159; PubMed=17254797; PubMed=24116068; PubMed=25877200; PubMed=31378681; RCB; TKG

Markers:
AmelogeninX,Y
CSF1PO10,11
D1S165611,12
D2S44111.3,14
D2S133819,20
D3S135815,16
D5S81811,12
D7S82010
D8S117915,16 (DSMZ; Genomics_Center_BCF_Technion; PubMed=24116068; PubMed=25877200)
15,16,17 (CLS)
D10S124813
D12S39121,25
D13S3179,13
D16S53912,13
D18S5113,14
D19S43315.2 (CCRID; CLS; Genomics_Center_BCF_Technion; PubMed=24116068)
16 (DSMZ)
D21S1129,31
D22S104516
DYS39112
FGA22,25
Penta D9,13
Penta E15,20
TH019
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Web pageshttps://en.wikipedia.org/wiki/Hep_G2
https://www.atcc.org/en/support/technical-support/faqs/growth-and-morphology-of-atcc-hb-8065
https://lccl.zucmanlab.com/hcc/cellLines/HepG2
https://www.phe-culturecollections.org.uk/media/134737/hep-g2-cell-line-profile.pdf
http://www.cells-talk.com/index.php/page/copelibrary?key=HepG2
https://www.proteinatlas.org/learn/cellines
http://141.61.102.20/mxdb/project/show/9191407937500
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-104.html
https://tcpaportal.org/mclp/
Cell line collections (Providers)Abcam; ab257304
Abcam; ab275467
AddexBio; C0015002/46
ATCC; HB-8065
BCRC; 60025
BCRJ; 0103
CCTCC; GDC0024
CLS; 300198
DSMZ; ACC-180
ECACC; 85011430
IBRC; C10096
ICLC; HTL95005
IZSLER; BS TCL 79
JCRB; JCRB1054
JCRB; NIHS0326 - Discontinued
KCB; KCB 200507YJ
KCLB; 88065
NCBI_Iran; C158
RCB; RCB0459 - Discontinued
RCB; RCB1648
RCB; RCB1886
TKG; TKG 0205
Chemistry resourcesChEMBL-Cells; CHEMBL3307718
ChEMBL-Targets; CHEMBL395
PharmacoDB; HepG2_539_2019
PubChem_Cell_line; CVCL_0027
Encyclopedic resourcesWikidata; Q5731621
Experimental variables resourcesEFO; EFO_0001187

更多>>相关产品

总部地址:北京市怀柔区渤海镇怀沙路536号

关注我们
在线咨询
在线客服
电话咨询
微信客服
返回顶部