huh-7.5.1人肝癌细胞

价 格:¥1800

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-1079

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameHuh-7.5.1
SynonymsHuh 7.5.1; Huh7.5.1
AccessionBTCC-1079
Resource Identification InitiativeTo cite this cell line use: Huh-7.5.1 (BTCC-1079)
CommentsPopulation: Japanese.
Virology: Compared to the parent Huh-7 cell line, permits improved HCV production when infected with strain JFH-1.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 6307; KDR; Simple; p.Gln472His (c.1416A>T); ClinVar=VCV000134603; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 20932; POLD3; Simple; p.Lys109Arg (c.326A>G) (p.Lys70Arg, c.209A>G); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 19102; RIGI; Simple; p.Thr55Ile (c.164C>T); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
DiseaseAdult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
HierarchyParent: CVCL_7927 (Huh-7.5)
Children:


CVCL_YU21 (Huh7.5.1-5)CVCL_YU20 (Huh7.5.1-8)
Sex of cellMale
Age at sampling57Y
CategoryCancer cell line
Publications

PubMed=15939869; DOI=10.1073/pnas.0503596102
Zhong J., Gastaminza P., Cheng G.-F., Kapadia S., Kato T., Burton D.R., Wieland S.F., Uprichard S.L., Wakita T., Chisari F.V.
Robust hepatitis C virus infection in vitro.
Proc. Natl. Acad. Sci. U.S.A. 102:9294-9299(2005)

PubMed=23285155; DOI=10.1371/journal.pone.0052697
Murayama A., Sugiyama N., Yoshimura S., Ishihara-Sugano M., Masaki T., Kim S., Wakita T., Mishiro S., Kato T.
A subclone of HuH-7 with enhanced intracellular hepatitis C virus production and evasion of virus related-cell cycle arrest.
PLoS ONE 7:E52697-E52697(2012)

PubMed=25420655; DOI=10.7883/yoken.JJID.2014.231
Shirasago Y., Sekizuka T., Saito K., Suzuki T., Wakita T., Hanada K., Kuroda M., Abe R., Fukasawa M.
Isolation and characterization of an Huh.7.5.1-derived cell clone highly permissive to hepatitis C virus.
Jpn. J. Infect. Dis. 68:81-88(2015)

Cross-references
Anatomy/cell type resourcesBTO; BTO:0005463
Cell line collections (Providers)CCTCC; GDC0137
Chemistry resourcesChEMBL-Cells; CHEMBL4483152
ChEMBL-Targets; CHEMBL4483247
PubChem_Cell_line; CVCL_E049
Encyclopedic resourcesWikidata; Q54896857
Entry history
Entry creation22-Oct-2012
Last entry update29-Jun-2023
Version number21

更多>>相关产品

总部地址:北京市怀柔区渤海镇怀沙路536号

关注我们
在线咨询
在线客服
电话咨询
微信客服
返回顶部