JAR人胎盘绒毛癌细胞

价 格:¥1800

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-1083

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameJAR
SynonymsJar; JAr; JaR
AccessionBTCC-1083
Resource Identification InitiativeTo cite this cell line use: JAR (BTCC-1083)
CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Doubling time: ~20-30 hours (DSMZ=ACC-462).
Karyotypic information: Near triploid karyotype (PubMed=33096371).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Caution: Established from the trophoblastic tumor of the placenta of a 24 year old woman, but the cell line is from the male fetus.
Genome ancestrySource: PubMed=30894373

Origin% genome


African30.11
Native American0.66
East Asian, North2.4
East Asian, South0
South Asian1.4
European, North42.28
European, South23.14
DiseaseGestational choriocarcinoma (NCIt: C4646)
Gestational choriocarcinoma (ORDO: Orphanet_99926)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
HierarchyChildren:



CVCL_XY25 (JAR-G1)CVCL_XY26 (JAR-G1s)CVCL_B7MU (JAR-Smad3/c)
Sex of cellMale
Age at samplingFetus
CategoryCancer cell line
STR profileSource(s): ATCC; CLS; Cosmic-CLP; DSMZ; KCLB

Markers:
AmelogeninX,Y
CSF1PO7,10
D2S133820,21
D3S135814 (CLS)
14,16,17 (DSMZ)
16,17 (KCLB)
D5S81810,11
D7S82010,11
D8S117914,16
D13S31711
D16S5399,10
D18S5113,17 (CLS)
14,15 (DSMZ)
D19S43312,13
D21S1128,29 (DSMZ)
30 (CLS)
FGA22
Penta D9,11 (CLS)
9,14 (DSMZ)
Penta E10,12 (CLS)
8,12 (DSMZ)
TH016,7
TPOX8,11
vWA16,18

Run an STR similarity search on this cell line
Publications

DOI=10.1007/BF02619074
Pattillo R.A., Ruckert A.C.F., Hussa R.O., Bernstein R., Delfs E.
The JAr cell line -- continuous human multihormone production and controls.
In Vitro 6:398-399(1971)

PubMed=7153601
Sasaki S., Katayama P.K., Roesler M., Pattillo R.A., Mattingly R.F., Ohkawa K.
Cytogenetic analysis of choriocarcinoma cell lines.
Nihon Sanka Fujinka Gakkai Zasshi 34:2253-2256(1982)

PubMed=4038916; DOI=10.1016/0165-4608(85)90052-4
Sheppard D.M., Fisher R.A., Lawler S.D.
Karyotypic analysis and chromosome polymorphisms in four choriocarcinoma cell lines.
Cancer Genet. Cytogenet. 16:251-258(1985)

PubMed=2878840; DOI=10.1016/0020-7292(86)90088-3
Yamashita K., Nakamura T., Shimizu T., Katagiri M., Ikeda H.
Expression of HLA class I and class II antigens in human choriocarcinoma cell lines.
Int. J. Gynecol. Obstet. 24:301-307(1986)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=2720636; DOI=10.1016/0165-4608(89)90664-X
Surti U., Habibian R.
Chromosomal rearrangement in choriocarcinoma cell lines.
Cancer Genet. Cytogenet. 38:229-240(1989)

PubMed=7937597; DOI=10.1016/0143-4004(94)90008-6
Grummer R., Hohn H.-P., Mareel M.M., Denker H.-W.
Adhesion and invasion of three human choriocarcinoma cell lines into human endometrium in a three-dimensional organ culture system.
Placenta 15:411-429(1994)

PubMed=7716126; DOI=10.1016/0143-4004(95)90079-9
Mitchell A.M., Yap A.S., Payne E.J., Manley S.W., Mortimer R.H.
Characterization of cell polarity and epithelial junctions in the choriocarcinoma cell line, JAR.
Placenta 16:31-39(1995)

PubMed=7819056; DOI=10.1038/bjc.1995.3
Yaginuma Y., Yamashita T., Takuma N., Katayama H., Ishikawa M.
Analysis of the p53 gene in human choriocarcinoma cell lines.
Br. J. Cancer 71:9-12(1995)

DOI=10.1007/0-306-46861-1_8
Ganapathy V., Prasad P.D., Leibach F.H.
Choriocarcinoma.
(In) Human cell culture. Vol. 2. Cancer Cell Lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.141-147; Kluwer Academic Publishers; New York (1999)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=24098444; DOI=10.1371/journal.pone.0076205
Vuoristo S., Toivonen S., Weltner J., Mikkola M., Ustinov J., Trokovic R., Palgi J., Lund R., Tuuri T., Otonkoski T.
A novel feeder-free culture system for human pluripotent stem cell culture and induced pluripotent stem cell derivation.
PLoS ONE 8:E76205-E76205(2013)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28161053; DOI=10.1016/j.placenta.2016.12.007
Abou-Kheir W., Barrak J., Hadadeh O., Daoud G.
HTR-8/SVneo cell line contains a mixed population of cells.
Placenta 50:1-7(2017)

PubMed=28724925; DOI=10.1038/s41598-017-06364-z
Rothbauer M., Patel N., Gondola H., Siwetz M., Huppertz B., Ertl P.
A comparative study of five physiological key parameters between four different human trophoblast-derived cell lines.
Sci. Rep. 7:5892-5892(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=33096371; DOI=10.1016/j.placenta.2020.10.011
Weber M., Weise A., Vasheghani F., Gohner C., Fitzgerald J.S., Liehr T., Markert U.R.
Cytogenomics of six human trophoblastic cell lines.
Placenta 103:72-75(2021)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line databases/resourcesCLO; CLO_0007011
MCCL; MCC:0000254
CCRID; 3101HUMTCHu156
Cell_Model_Passport; SIDM01039
Cosmic-CLP; 907175
DepMap; ACH-001529
DSMZCellDive; ACC-462
IGRhCellID; JAR
LINCS_LDP; LCL-1491
TOKU-E; 2064
Anatomy/cell type resourcesBTO; BTO:0001585
Biological sample resourcesBioSample; SAMN01821568
BioSample; SAMN01821637
BioSample; SAMN03472717
Cell line collections (Providers)ATCC; HTB-144
BCRC; 60491
CLS; 300221
DSMZ; ACC-462
IZSLER; BS TCL 182
KCLB; 30144
Chemistry resourcesChEMBL-Cells; CHEMBL3307657
ChEMBL-Targets; CHEMBL614587
GDSC; 907175
PharmacoDB; JAR_676_2019
PubChem_Cell_line; CVCL_0360
Encyclopedic resourcesWikidata; Q54898511
Experimental variables resourcesEFO; EFO_0002211
Gene expression databasesArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM827264
GEO; GSM1669947
Polymorphism and mutation databasesCosmic; 907175
Cosmic; 2077193
IARC_TP53; 21417
Progenetix; CVCL_0360
Proteomic databasesPRIDE; PXD030304
Sequence databasesEGA; EGAS00001000978

更多>>相关产品

总部地址:北京市怀柔区渤海镇怀沙路536号

关注我们
在线咨询
在线客服
电话咨询
微信客服
返回顶部