• Mutation; HGNC; 959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (PubMed=29739316).
  
• Mutation; HGNC; 959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (PubMed=29739316).
  
• Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; 6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (PubMed=29739316).
  
• Mutation; HGNC; 6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (PubMed=29739316).
  
• Mutation; HGNC; 7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (PubMed=29739316).
  
• Mutation; HGNC; 7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; 11491; SYK; Simple; p.Met34Hisfs*3 (c.98_99insG); Zygosity=Heterozygous (PubMed=7592872; PubMed=29739316).
  
• Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (PubMed=29739316).
  

PubMed=8316623; DOI=10.2307/3578190
Evans H.H., Ricanati M., Horng M.-F., Jiang Q.-Y., Mencl J., Olive P.L.
DNA double-strand break rejoining deficiency in TK6 and other human B-lymphoblast cell lines.
Radiat. Res. 134:307-315(1993)

PubMed=7592872; DOI=10.1074/jbc.270.44.26533
Fargnoli J., Burkhardt A.L., Laverty M., Kut S.A., van Oers N.S.C., Weiss A., Bolen J.B.
Syk mutation in Jurkat E6-derived clones results in lack of p72syk expression.
J. Biol. Chem. 270:26533-26537(1995)

PubMed=9707173; DOI=10.1096/fasebj.12.11.1007
Lewis M.L., Reynolds J.L., Cubano L.A., Hatton J.P., Lawless B.D., Piepmeier E.H.
Spaceflight alters microtubules and increases apoptosis in human lymphocytes (Jurkat).
FASEB J. 12:1007-1018(1998)

PubMed=10468210; DOI=10.1016/S0891-5849(99)00074-X
Schoene N.W., Kamara K.S.
Population doubling time, phosphatase activity, and hydrogen peroxide generation in Jurkat cells.
Free Radic. Biol. Med. 27:364-369(1999)

PubMed=10832058; DOI=10.1016/S0531-5565(00)00090-5
Cubano L.A., Lewis M.L.
Fas/APO-1 protein is increased in spaceflown lymphocytes (Jurkat).
Exp. Gerontol. 35:389-400(2000)

PubMed=11481229; DOI=10.1096/fj.00-0820fje
Lewis M.L., Cubano L.A., Zhao B.-T., Dinh H.-K., Pabalan J.G., Piepmeier E.H., Bowman P.D.
cDNA microarray reveals altered cytoskeletal gene expression in space-flown leukemic T lymphocytes (Jurkat).
FASEB J. 15:1783-1785(2001)

PubMed=11669127; DOI=10.1016/S0094-5765(01)00116-3
Schatten H., Lewis M.L., Chakrabarti A.
Spaceflight and clinorotation cause cytoskeleton and mitochondria changes and increases in apoptosis in cultured cells.
Acta Astronaut. 49:399-418(2001)

PubMed=15472075; DOI=10.1126/science.1102160
Weng A.P., Ferrando A.A., Lee W., Morris J.P. IV, Silverman L.B., Sanchez-Irizarry C., Blacklow S.C., Look A.T., Aster J.C.
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Science 306:269-271(2004)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=23933134; DOI=10.1016/j.jprot.2013.07.019
Storvold G.L., Landskron J., Strozynski M., Arntzen M.O., Koehler C.J., Kalland M.E., Tasken K., Thiede B.
Quantitative profiling of tyrosine phosphorylation revealed changes in the activity of the T cell receptor signaling pathway upon cisplatin-induced apoptosis.
J. Proteomics 91:344-357(2013)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25894527; DOI=10.1371/journal.pone.0121314
Bausch-Fluck D., Hofmann A., Bock T., Frei A.P., Cerciello F., Jacobs A., Moest H., Omasits U., Gundry R.L., Yoon C., Schiess R., Schmidt A., Mirkowska P., Hartlova A.S., Van Eyk J.E., Bourquin J.-P., Aebersold R., Boheler K.R., Zandstra P.W., Wollscheid B.
A mass spectrometric-derived cell surface protein atlas.
PLoS ONE 10:E0121314-E0121314(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=26546556; DOI=10.1016/j.jprot.2015.10.029
Nguyen T.D., Carrascal M., Vidal-Cortes O., Gallardo O., Casas V., Gay M., Phan V.C., Abian J.
The phosphoproteome of human Jurkat T cell clones upon costimulation with anti-CD3/anti-CD28 antibodies.
J. Proteomics 131:190-198(2016)

PubMed=28464451; DOI=10.1002/pmic.201600470
Tran T.T., Strozynski M., Thiede B.
Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells.
Proteomics 17:1600470.1-1600470.11(2017)

PubMed=29739316; DOI=10.1186/s12864-018-4718-6
Gioia L., Siddique A., Head S.R., Salomon D.R., Su A.I.
A genome-wide survey of mutations in the Jurkat cell line.
BMC Genomics 19:334.1-334.13(2018)

PubMed=32938764; DOI=10.1128/JVI.01334-20
Fernandez M.V., Hoffman H.K., Pezeshkian N., Tedbury P.R., van Engelenburg S.B., Freed E.O.
Elucidating the basis for permissivity of the MT-4 T-cell line to replication of an HIV-1 mutant lacking the gp41 cytoplasmic tail.
J. Virol. 94:e01334.20.1-e01334.20.27(2020)