MGC-803人胃癌细胞-BTCC典型培养物保藏中心-【BTCC细胞库】北京博沃尔斯生物科技有限公司官网

Cell line name

MGC-803

Synonyms

MGC803; MGc80-3

Accession

CVCL_5334

Resource Identification Initiative

To cite this cell line use: MGC-803 (RRID:CVCL_5334)

Comments

Problematic cell line: Possibly contaminated. May be a derivative of HeLa and another cell of unknown origin. The STR profile is highly similar to that of HeLa yet shows some specific differences that suggest a possible hybrid cell line.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00588.
Doubling time: 22.5 hours (PubMed=29683800).
Omics: Secretome proteome analysis by 2D-DE/MS.
Omics: Transcriptome analysis by microarray.
Miscellaneous: Formerly the CCRID database had 2 entries describing this cell line (3111C0001CCC000227, 3131C0001000700084). They were one of the sources for the STR profile of this entry.
Misspelling: BGC-803; Note=Occasionally.
Misspelling: BGC803; Note=Occasionally.
Misspelling: MCG803; GEO=GSM844588.

Disease

Gastric mucinous adenocarcinoma (NCIt: C5248)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:


CVCL_UI41 (MGC-803/5FU)	CVCL_UI42 (MGC-803/DDP)	CVCL_VG42 (MGC-803/PTX)
CVCL_UI43 (MGC-803/TA)

Sex of cell

Male

Age at sampling

53Y

Category

Cancer cell line

STR profile

Source(s): CCRID; PubMed=28107433; PubMed=28851942

Markers:

Amelogenin	X
CSF1PO	9,10,12
D2S441	10,11
D2S1338	17,24
D3S1358	15,18
D5S818	10,11,12
D6S1043	18,19
D7S820	11,12
D8S1179	12,14
D12S391	17,20,26
D13S317	7,13.3
D16S539	9,11
D18S51	13
D19S433	13
D21S11	27,28
FGA	18,21
Penta D	8,15
Penta E	7,10,16,17
TH01	7,9
TPOX	12
vWA	16,17,18

Web pages

https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

Publications

DOI=10.1007/BF02948354
Xiao H., Dong Z.-W., Shou C.-C.
Induction of apoptosis in human gastric carcinoma cell line MGC-803 by monoclonal antibody PD4.
Chin. J. Cancer Res. 10:169-173(1998)

PubMed=24743803
Huang H., Han Y., Wu J., Tian Z.-H., Qu L.-K., Shou C.-C.
Establishment of drug resistant cell line of MGC-803 and analysis of differential secretome.
Beijing Da Xue Xue Bao Yi Xue Ban 46:183-189(2014)

PubMed=28107433; DOI=10.1371/journal.pone.0170384
Huang Y.-Q., Liu Y.-H., Zheng C.-Y., Shen C.
Investigation of cross-contamination and misidentification of 278 widely used tumor cell lines.
PLoS ONE 12:E0170384-E0170384(2017)

PubMed=28851942; DOI=10.1038/s41598-017-09660-w
Bian X.-C., Yang Z.-L., Feng H.-L., Sun H., Liu Y.-Q.
A combination of species identification and STR profiling identifies cross-contaminated cells from 482 human tumor cell lines.
Sci. Rep. 7:9774-9774(2017)

PubMed=29683800; DOI=10.1097/CAD.0000000000000601
Fu L., Yin F., Li X.-R., Han B.-K., Zhang C., Wang J.-W., Wang Y.-Q., Bi Y.-F., Liu H.-M.
Generation and characterization of a paclitaxel-resistant human gastric carcinoma cell line.
Anticancer Drugs 29:491-502(2018)

PubMed=29717028; DOI=10.1042/BSR20180277
Zhang Y.-Q., Yu S., Zhang Z.-Z., Zhao G., Xu J.
Long non-coding RNA AK096174 promotes cell proliferation and invasion in gastric cancer by regulating WDR66 expression.
Biosci. Rep. 38:BSR20180277.1-BSR20180277.12(2018)

Cross-references

Anatomy/cell type resources

BTO; BTO:0004953

Chemistry resources

ChEMBL-Cells; CHEMBL3706567
ChEMBL-Targets; CHEMBL3706566
PubChem_Cell_line; CVCL_5334

Encyclopedic resources

Wikidata; Q54905425

Experimental variables resources

EFO; EFO_0006286

Gene expression databases

GEO; GSM844588
GEO; GSM1374671

Polymorphism and mutation databases

Cosmic; 2267321
IARC_TP53; 24858

质检报告（COA）
Markers:

Amelogenin	X
CSF1PO	9,10,12
D2S441	10,11
D2S1338	17,24
D3S1358	15,18
D5S818	10,11,12
D6S1043	18,19
D7S820	11,12
D8S1179	12,14
D12S391	17,20,26
D13S317	7,13.3
D16S539	9,11
D18S51	13
D19S433	13
D21S11	27,28
FGA	18,21
Penta D	8,15
Penta E	7,10,16,17
TH01	7,9
TPOX	12
vWA	16,17,18

MGC-803人胃癌细胞

详细资料说明书下载质检报告（COA）

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