NALM-6人前B急性淋巴细胞白血病细胞

价 格:¥1800

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-1117

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameNALM-6
SynonymsNalm-6; NALM 6; Nalm 6; NALM6; Nalm6; NALM-6-M1
AccessionBTCC-1117
Resource Identification InitiativeTo cite this cell line use: NALM-6 (BTCC-1117)
CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Part of: LL-100 blood cancer cell line panel.
Part of: MD Anderson Cell Lines Project.
Part of: NCI Pediatric Preclinical Testing Program (PPTP) cell line panel.
Population: Caucasian.
Doubling time: 25 hours (PubMed=25984343); 19 hours (PubMed=20922763); 40.2 hours (PubMed=8847894); ~36 hours (DSMZ=ACC-128).
Microsatellite instability: Instable (MSI-high) (PubMed=10739008; PubMed=11226526; PubMed=31068700; Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Deep quantitative proteome analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: shRNA library screening.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 3236; EGFR; Simple; p.Arg1068Ter (c.3202C>T); Zygosity=Heterozygous (Cosmic-CLP; DepMap).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Ala146Thr (c.436G>A); Zygosity=Heterozygous (PubMed=16969076; Cosmic-CLP; DepMap).
  • Mutation; HGNC; 9864; RARA; Simple; p.Gln45Ter (c.133C>T); ClinVar=VCV000393019; Zygosity=Heterozygous (Cosmic-CLP; DepMap).
HLA typingSource: PubMed=2939141
Class I
HLA-AA*01,02
HLA-BB*15

Source: PubMed=83966
Class I
HLA-AA*01,02
HLA-BB*08,15

Source: PubMed=26589293
Class I
HLA-AA*01:01,02:01
HLA-BB*08:01,15:01
HLA-CC*04:01,07:01

Source: DSMZCellDive=ACC-128
Class I
HLA-AA*01:01:01,02:01:01
HLA-BB*08:01:01,15:01:01
HLA-CC*04:01:01,07:01:01
Class II
HLA-DPDPA1*01:03:01,01:03:01

DPB1*04:01:01,04:01:01
HLA-DQDQA1*02:01:01,02:01:01

DQB1*02:01:01,03:03:02
HLA-DRDRA*01:01:02,01:02:02

DRB1*03:01:01,07:01:01
Genome ancestrySource: PubMed=30894373

Origin% genome


African0.12
Native American0.55
East Asian, North0
East Asian, South2.1
South Asian0
European, North75.01
European, South22.21
DiseaseAdult B acute lymphoblastic leukemia (NCIt: C9143)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
HierarchyChildren:



CVCL_8173 (BLIN-1)CVCL_8260 (LR10.6)CVCL_UJ07 (N6-1000)
CVCL_UJ08 (N6-500)CVCL_C4PE (N6-KU70-2-DG)CVCL_UJ06 (N6/ADR)
CVCL_HE04 (NALM-6 DCLRE1C(-/-))CVCL_HE05 (NALM-6 LIG4(-/-))CVCL_HE06 (NALM-6 MUS81(-/-))
CVCL_A4IJ (NALM-6 POLB (-/-))CVCL_HE07 (NALM-6 PRKDC(+/-))CVCL_HE08 (NALM-6 RAD54L(-/-))
CVCL_HE09 (NALM-6 TOP1(+/-))CVCL_HE10 (NALM-6 TOP2B(-/-))CVCL_HE11 (NALM-6 TP53(+/-))
CVCL_HE12 (NALM-6 TP53(-/-))CVCL_HE13 (NALM-6 XRCC5(+/-))CVCL_J365 (Nalm-6-MSH+)
CVCL_UD71 (Nalm-6-MSH+/TK+/-)CVCL_UD96 (Nalm-6-TK+/-)CVCL_B7AM (NALM-6/H)
CVCL_B7AN (NALM-6/HDR)CVCL_0U51 (NALM-6/SP-B)CVCL_UJ05 (NALM6, clone G5)
CVCL_RA33 (Nalm6-eGFP-Puro)CVCL_RA35 (Nalm6-Fluc-hNIS)CVCL_RA34 (Nalm6-Fluc-Neo/eGFP-Puro)
CVCL_RA36 (Nalm6-Fluc-Puro)CVCL_4V57 (NALM6/Clo)CVCL_8270 (PBEI)
CVCL_JH08 (POLZ CD MSH-)CVCL_M249 (POLZ KO MSH-)
Originate from same individualCVCL_WW76 ! B85
CVCL_5677 ! NALM-7
CVCL_L057 ! NALM-8
CVCL_L058 ! NALM-9
CVCL_L059 ! NALM-10
CVCL_L060 ! NALM-11
CVCL_5660 ! NALM-12
CVCL_L061 ! NALM-13
Sex of cellMale
Age at sampling19Y
CategoryCancer cell line
STR profileSource(s): AddexBio; COG; Cosmic-CLP; DSMZ; PubMed=11416159; PubMed=20922763; PubMed=25877200; PubMed=34823530; RCB; TKG

Markers:
AmelogeninX,Y
CSF1PO12 (AddexBio; COG; Cosmic-CLP; DSMZ; PubMed=25877200)
12,13 (PubMed=20922763; PubMed=34823530)
13 (RCB; TKG)
D2S44110,14
D2S133817,24
D3S135815,16,17 (PubMed=20922763)
16,17 (COG; DSMZ; PubMed=25877200; PubMed=34823530)
D5S81810,11,12 (COG; DSMZ; PubMed=25877200)
11 (AddexBio)
11,12 (Cosmic-CLP; PubMed=20922763; PubMed=34823530; RCB; TKG)
D6S104311
D7S8208,12 (AddexBio)
8,9,10 (Cosmic-CLP; DSMZ; PubMed=25877200)
8,10 (PubMed=34823530)
8,11 (RCB; TKG)
8,11,12 (PubMed=20922763)
10 (COG)
D8S117911,13,14 (COG; DSMZ; PubMed=25877200)
12,13 (PubMed=20922763)
D13S3178,9,11,12 (DSMZ; PubMed=34823530)
8,9,12 (COG)
9,11 (AddexBio)
9,12 (Cosmic-CLP; PubMed=25877200)
9,12,13 (PubMed=20922763)
9,13 (RCB; TKG)
D16S5399,10,11 (COG; DSMZ; PubMed=34823530)
10,11 (Cosmic-CLP; PubMed=20922763; PubMed=25877200; RCB; TKG)
11 (AddexBio)
D18S5111,12,14,15 (PubMed=20922763)
12,15 (COG; DSMZ; PubMed=25877200)
D19S43312,13,15 (PubMed=20922763)
13,15 (COG; DSMZ)
D21S1128,29
FGA21,22 (COG)
21,22,23 (DSMZ)
22 (PubMed=11416159; PubMed=25877200)
22,23 (PubMed=20922763; PubMed=34823530)
Penta D8,14
Penta E11
TH018 (PubMed=11416159; PubMed=25877200)
8,9 (AddexBio; COG; Cosmic-CLP; DSMZ; PubMed=20922763; PubMed=34823530; RCB; TKG)
TPOX8,10
vWA15,16 (COG; Cosmic-CLP; DSMZ; PubMed=20922763; PubMed=25877200; PubMed=34823530; RCB; TKG)
15,18 (AddexBio)

Run an STR similarity search on this cell line
Web pageshttps://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/n/cell-lines-detail-607.html
http://www.cccells.org/cellreqs-ncipptp.php
http://www.pptpinvitro.org/cell_lines_panel.php
https://tcpaportal.org/mclp/
Publications

CLPUB00085
Minowada J., Oshimura M., Abe S., Greaves M.F., Janossy G., Sandberg A.A.
Human leukemia cell lines. Evidence for differentiation toward T- and B-cell axis within a leukemia clone.
Proc. Am. Assoc. Cancer Res. 19:109-109(1978)

PubMed=155647
Han T., Minowada J.
Use of stimulating capacity of mixed lymphocyte reaction (MLR-S) as a possible marker for the cell-origin of null-cell acute lymphoblastic leukaemia.
Immunology 35:333-339(1978)

PubMed=83966; DOI=10.1002/ijc.2910230206
Hurwitz R., Hozier J., LeBien T.W., Minowada J., Gajl-Peczalska K., Kubonishi I., Kersey J.H.
Characterization of a leukemic cell line of the pre-B phenotype.
Int. J. Cancer 23:174-180(1979)

PubMed=2985879; DOI=10.1016/0145-2126(85)90084-0
Drexler H.G., Gaedicke G., Minowada J.
Isoenzyme studies in human leukemia-lymphoma cell lines -- 1 carboxylic esterase.
Leuk. Res. 9:209-229(1985)

PubMed=3159941; DOI=10.1016/0145-2126(85)90134-1
Drexler H.G., Gaedicke G., Minowada J.
Isoenzyme studies in human leukemia-lymphoma cell lines -- III Beta-hexosaminidase (E.C. 3.2.1.30).
Leuk. Res. 9:549-559(1985)

PubMed=3874327; DOI=10.1016/0145-2126(85)90133-x
Drexler H.G., Gaedicke G., Minowada J.
Isoenzyme studies in human leukemia-lymphoma cells lines -- II. Acid phosphatase.
Leuk. Res. 9:537-548(1985)

PubMed=2415623; DOI=10.4049/jimmunol.136.1.320
Goldmacher V.S., Lambert J.M., Young A.Y., Anderson J., Tinnel N.L., Kornacki M., Ritz J., Blattler W.A.
Expression of the common acute lymphoblastic leukemia antigen (CALLA) on the surface of individual cells of human lymphoblastoid lines.
J. Immunol. 136:320-325(1986)

PubMed=2939141; DOI=10.4049/jimmunol.136.11.4311
Pesando J.M., Graf L.
Differential expression of HLA-DR, -DQ, and -DP antigens on malignant B cells.
J. Immunol. 136:4311-4318(1986)

PubMed=2783384
Luo Y., Hara H., Haruta Y., Seon B.K.
Establishment of ascitic tumor of human pre-B acute lymphoblastic leukemia in nonconditioned nude mice.
Cancer Res. 49:706-710(1989)

PubMed=2140233; DOI=10.1111/j.1440-1827.1990.tb01549.x
Nakano A., Harada T., Morikawa S., Kato Y.
Expression of leukocyte common antigen (CD45) on various human leukemia/lymphoma cell lines.
Acta Pathol. Jpn. 40:107-115(1990)

PubMed=8847894
Tani A., Tatsumi E., Nakamura F., Kumagai S., Kosaka Y., Sano K., Nakamura H., Amakawa R., Ohno H.
Sensitivity to dexamethasone and absence of bcl-2 protein in Burkitt's lymphoma cell line (Black93) derived from a patient with acute tumor lysis syndrome: comparative study with other BL and non-BL lines.
Leukemia 10:1592-1603(1996)

PubMed=9067587; DOI=10.1038/sj.leu.2400571
Uphoff C.C., MacLeod R.A.F., Denkmann S.A., Golub T.R., Borkhardt A., Janssen J.W.G., Drexler H.G.
Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines.
Leukemia 11:441-447(1997)

PubMed=9510473; DOI=10.1111/j.1349-7006.1998.tb00476.x
Hosoya N., Hangaishi A., Ogawa S., Miyagawa K., Mitani K., Yazaki Y., Hirai H.
Frameshift mutations of the hMSH6 gene in human leukemia cell lines.
Jpn. J. Cancer Res. 89:33-39(1998)

PubMed=9680106; DOI=10.1016/S0145-2126(98)00050-2
Matsuo Y., Drexler H.G.
Establishment and characterization of human B cell precursor-leukemia cell lines.
Leuk. Res. 22:567-579(1998)

PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x
Takizawa J., Suzuki R., Kuroda H., Utsunomiya A., Kagami Y., Joh T., Aizawa Y., Ueda R., Seto M.
Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia.
Jpn. J. Cancer Res. 89:712-718(1998)

PubMed=10490826; DOI=10.1038/sj.onc.1202874
Fu X.-Y., McGrath S., Pasillas M., Nakazawa S., Kamps M.P.
EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1.
Oncogene 18:4920-4929(1999)

PubMed=10695022
Matsuo Y., Nishizaki C., Drexler H.G.
Efficient DNA fingerprinting method for the identification of cross-culture contamination of cell lines.
Hum. Cell 12:149-154(1999)

PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4
Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.
Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines.
Leuk. Res. 24:255-262(2000)

PubMed=11021758; DOI=10.1038/sj.leu.2401891
Majka M., Rozmyslowicz T., Honczarenko M., Ratajczak J., Wasik M.A., Gaulton G.N., Ratajczak M.Z.
Biological significance of the expression of HIV-related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines.
Leukemia 14:1821-1832(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1
Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.
Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000),255-262.
Leuk. Res. 25:275-278(2001)

PubMed=11986953; DOI=10.1038/sj.leu.2402485
O'Donnell P.H., Guo W.-X., Reynolds C.P., Maurer B.J.
N-(4-hydroxyphenyl)retinamide increases ceramide and is cytotoxic to acute lymphoblastic leukemia cell lines, but not to non-malignant lymphocytes.
Leukemia 16:902-910(2002)

PubMed=15843827; DOI=10.1038/sj.leu.2403749
Andersson A., Eden P., Lindgren D., Nilsson J., Lassen C., Heldrup J., Fontes M., Borg A., Mitelman F., Johansson B., Hoglund M., Fioretos T.
Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations.
Leukemia 19:1042-1050(2005)

PubMed=16405397; DOI=10.1089/dna.2006.25.19
Adachi N., So S., Iiizumi S., Nomura Y., Murai K., Yamakawa C., Miyagawa K., Koyama H.
The human pre-B cell line Nalm-6 is highly proficient in gene targeting by homologous recombination.
DNA Cell Biol. 25:19-24(2006)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=16969076; DOI=10.4161/cbt.5.8.3251
Edkins S., O'Meara S., Parker A., Stevens C., Reis M., Jones S., Greenman C., Davies H., Dalgliesh G.L., Forbes S., Hunter C., Smith R., Stephens P.J., Goldstraw P., Nicholson A., Chan T.L., Velculescu V.E., Yuen S.T., Leung S.Y., Stratton M.R., Futreal P.A.
Recurrent KRAS codon 146 mutations in human colorectal cancer.
Cancer Biol. Ther. 5:928-932(2006)

PubMed=20103924
Adachi N., Nishijima H., Shibahara K.-I.
Gene targeting using the human Nalm-6 pre-B cell line.
Biosci. Trends 2:169-180(2008)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=20575032; DOI=10.1002/ajh.21738
Inukai T., Zhang X.-R., Kameyama T., Suzuki Y., Yoshikawa K., Kuroda I., Nemoto A., Akahane K., Sato H., Goi K., Nakamoto K., Hamada J.-I., Tada M., Moriuchi T., Sugita K.
A specific linkage between the incidence of TP53 mutations and type of chromosomal translocations in B-precursor acute lymphoblastic leukemia cell lines.
Am. J. Hematol. 85:535-537(2010)

PubMed=20922763; DOI=10.1002/pbc.22801
Kang M.H., Smith M.A., Morton C.L., Keshelava N., Houghton P.J., Reynolds C.P.
National Cancer Institute pediatric preclinical testing program: model description for in vitro cytotoxicity testing.
Pediatr. Blood Cancer 56:239-249(2011)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=23596518; DOI=10.1371/journal.pone.0061189
Suzuki T., Ukai A., Honma M., Adachi N., Nohmi T.
Restoration of mismatch repair functions in human cell line Nalm-6, which has high efficiency for gene targeting.
PLoS ONE 8:E61189-E61189(2013)

PubMed=25984343; DOI=10.1038/sdata.2014.35
Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G.-Z., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E.T., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H.-B., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Meyers B.H., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=30285677; DOI=10.1186/s12885-018-4840-5
Tan K.-T., Ding L.-W., Sun Q.-Y., Lao Z.-T., Chien W., Ren X., Xiao J.-F., Loh X.-Y., Xu L., Lill M., Mayakonda A., Lin D.-C., Yang H., Koeffler H.P.
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
BMC Cancer 18:940.1-940.13(2018)

PubMed=30629668; DOI=10.1371/journal.pone.0210404
Uphoff C.C., Pommerenke C., Denkmann S.A., Drexler H.G.
Screening human cell lines for viral infections applying RNA-Seq data analysis.
PLoS ONE 14:E0210404-E0210404(2019)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x
Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M., MacLeod R.A.F., Nagel S., Steube K., Uphoff C.C., Drexler H.G.
The LL-100 panel: 100 cell lines for blood cancer studies.
Sci. Rep. 9:8218-8218(2019)

PubMed=31978347; DOI=10.1016/j.cell.2019.12.023
Nusinow D.P., Szpyt J., Ghandi M., Rose C.M., McDonald E.R. III, Kalocsay M., Jane-Valbuena J., Gelfand E.T., Schweppe D.K., Jedrychowski M.P., Golji J., Porter D.A., Rejtar T., Wang Y.K., Kryukov G.V., Stegmeier F., Erickson B.K., Garraway L.A., Sellers W.R., Gygi S.P.
Quantitative proteomics of the Cancer Cell Line Encyclopedia.
Cell 180:387-402.e16(2020)

PubMed=34823530; DOI=10.1186/s12935-021-02335-7
Li Y.-Y., Zuo C., Gu L.
Characterization of a novel glucocorticoid-resistant human B-cell acute lymphoblastic leukemia cell line, with AMPK, mTOR and fatty acid synthesis pathway inhibition.
Cancer Cell Int. 21:623.1-623.14(2021)

PubMed=35354797; DOI=10.1038/s41467-022-29224-5
Leo I.R., Aswad L., Stahl M., Kunold E., Post F., Erkers T., Struyf N., Mermelekas G., Joshi R.N., Gracia-Villacampa E., Ostling P., Kallioniemi O.-P., Pokrovskaja Tamm K., Siavelis I., Lehtio J., Vesterlund M., Jafari R.
Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.
Nat. Commun. 13:1691.1-1691.19(2022)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line databases/resourcesCLO; CLO_0007938
CLO; CLO_0050970
CLDB; cl3631
CLDB; cl3632
Cell_Model_Passport; SIDM00429
Cosmic-CLP; 908158
DepMap; ACH-000938
DSMZCellDive; ACC-128
IGRhCellID; NALM6
LINCS_LDP; LCL-1007
Lonza; 812
Anatomy/cell type resourcesBTO; BTO:0003288
Biological sample resourcesBioSample; SAMN03472035
BioSample; SAMN03473163
BioSample; SAMN03473413
BioSample; SAMN10988491
Cell line collections (Providers)AddexBio; C0003030/5015
CLS; 300297
DSMZ; ACC-128
NCBI_Iran; C212
RCB; RCB1933
TKG; TKG 0413
Chemistry resourcesChEMBL-Cells; CHEMBL3307559
ChEMBL-Targets; CHEMBL614187
GDSC; 908158
PharmacoDB; NALM6_980_2019
PubChem_Cell_line; CVCL_0092
Encyclopedic resourcesWikidata; Q54907426
Experimental variables resourcesEFO; EFO_0002245

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