NOZ人胆囊癌细胞

价 格:¥1800

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-1138

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameNOZ
SynonymsNOZAWA; NOZC-1
AccessionBTCC-1138
Resource Identification InitiativeTo cite this cell line use: NOZ (BTCC-1138)
CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: 40-48 hours (CelloPub=CLPUB00469); 30 hours (PubMed=32293552); 48 hours (PubMed=3154020); 30 hours (Note=Lot 09162008) (JCRB=JCRB1033).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Misspelling: NO2; Cosmic=2629294.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Unspecified (DepMap).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln331Ter (c.991C>T); ClinVar=VCV000922893; Zygosity=Unspecified (DepMap).
DiseaseGallbladder carcinoma (NCIt: C3844)
Carcinoma of gallbladder and extrahepatic biliary tract (ORDO: Orphanet_56044)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cellFemale
Age at sampling48Y
CategoryCancer cell line
STR profileSource(s): DepMap; JCRB

Markers:
AmelogeninX
CSF1PO11,13
D3S135815,17
D5S81811,13
D7S82010,11
D8S11799,14
D13S3178,12
D16S5399,11
D18S5112
D21S1130,31
FGA17
Penta D11,13
Penta E12,17
TH017,9
TPOX8,11
vWA19

Run an STR similarity search on this cell line
Publications

CLPUB00469
Homma S.
Studies on the establishment and some biological characteristics of cultured human liver cancer cell lines. Their growth, functional and morphological characteristics and temperature sensitivities.
Jikeikai Med. J. 32:289-315(1985)

PubMed=3154020
Homma S., Hasumura S., Nagamori S., Kameda H.
Establishment and characterization of a human gall bladder carcinoma cell line NOZ.
Hum. Cell 1:95-97(1988)

PubMed=2543327
Hasumura S., Nagamori S., Fujise K., Homma S., Sujino H., Matsuura T., Shimizu K., Niiya M., Kameda H.
Combination therapy of hyperthermia and other methods in liver and bile tract cancers -- evaluation of these methods using cancer cell lines in vitro.
Gan To Kagaku Ryoho 16:1905-1912(1989)

DOI=10.1007/BF02348185
Kawada M., Aizaki H., Fukaya K.-I., Niiya M., Matsuura T., Sujino H., Hasumura S., Nagamori S., Toda G.
Morphological changes in human gall bladder carcinoma cell line-NOZ due to epirubicin and doxorubicin.
Med. Electron Microsc. 27:175-177(1994)

PubMed=32293552; DOI=10.1186/s40659-020-00282-7
Garcia P., Bizama C., Rosa L., Espinoza J.A., Weber H., Cerda-Infante J., Sanchez M., Montecinos V.P., Lorenzo-Bermejo J., Boekstegers F., Davila-Lopez M., Alfaro F., Leiva-Acevedo C., Parra Z., Romero D., Kato S., Leal P., Lagos M., Roa J.C.
Functional and genomic characterization of three novel cell lines derived from a metastatic gallbladder cancer tumor.
Biol. Res. 53:13.1-13.17(2020)

PubMed=32899426; DOI=10.3390/cancers12092510
Scherer D., Davila Lopez M., Goeppert B., Abrahamsson S., Gonzalez Silos R., Nova I., Marcelain K., Roa J.C., Ibberson D., Umu S.U., Rounge T.B., Roessler S., Lorenzo-Bermejo J.
RNA sequencing of hepatobiliary cancer cell lines: data and applications to mutational and transcriptomic profiling.
Cancers (Basel) 12:2510.1-2510.14(2020)

Cross-references
Cell line databases/resourcesCell_Model_Passport; SIDM01812
DepMap; ACH-001607
Biological sample resourcesBioSample; SAMN03472480
Cell line collections (Providers)JCRB; JCRB1033
JCRB; NIHS0283 - Discontinued
Encyclopedic resourcesWikidata; Q54930937
Polymorphism and mutation databasesCosmic; 1122352
Cosmic; 2629294
Cosmic; 2674061

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