BPH-1人前列腺增生细胞(STR鉴定正确)

价 格:¥3000

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-1452

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameBPH-1
SynonymsBPH1; Benign Prostatic Hyperplasia-1
AccessionBTCC-1452
Resource Identification InitiativeTo cite this cell line use: BPH-1 (RRID:BTCC-1452)
CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Caucasian.
Doubling time: ~50 hours (DSMZ=ACC-143).
Microsatellite instability: Stable (MSS) (Sanger).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Genome ancestrySource: PubMed=30894373

Origin% genome


African0
Native American0
East Asian, North1.5
East Asian, South0.02
South Asian2.82
European, North66.48
European, South29.17
DiseaseBenign prostatic hyperplasia (NCIt: C2897)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
HierarchyChildren:



CVCL_4751 (BPH-1 TETD-A)CVCL_4752 (BPH-1 TETD-B)CVCL_4753 (BPH-1-CAFTD-01)
CVCL_4755 (BPH-1-CAFTD-03)CVCL_4757 (BPH-1-CAFTD-05)CVCL_4759 (BPH-1-CAFTD-07)
Sex of cellMale
Age at sampling68Y
CategoryTransformed cell line
STR profileSource(s): Cosmic-CLP=924105; DepMap=ACH-001453; DSMZ=ACC-143; Millipore=SCC256; PubMed=11304728

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133817
D3S135816
D5S81811,12
D7S82010,11
D8S117910,15
D13S31711,12
D16S5399
D18S5110,16
D19S43312,15
D21S1128,32.2
FGA21,24 (DepMap=ACH-001453; DSMZ=ACC-143; PubMed=11304728)
24 (Millipore=SCC256)
Penta D9,14
Penta E7,10
TH016,7
TPOX8,12
vWA17

Run an STR similarity search on this cell line
Web pagesInfo; CaP CLDb; -; https://web.archive.org/web/20150602153427/http://capcelllines.ca:80/details.asp?id=132
Publications

PubMed=7535634; DOI=10.1007/BF02631333
Hayward S.W., Dahiya R., Cunha G.R., Bartek J., Deshpande N., Narayan P.
Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1.
In Vitro Cell. Dev. Biol. Anim. 31:14-24(1995)

PubMed=11304728; DOI=10.1002/pros.1045
van Bokhoven A., Varella-Garcia M., Korch C.T., Hessels D., Miller G.J.
Widely used prostate carcinoma cell lines share common origins.
Prostate 47:36-51(2001)

PubMed=11719443
Phillips J.L., Hayward S.W., Wang Y.-Z., Vasselli J., Pavlovich C.P., Padilla-Nash H.M., Pezullo J.R., Ghadimi B.M., Grossfeld G.D., Rivera A., Linehan W.M., Cunha G.R., Ried T.
The consequences of chromosomal aneuploidy on gene expression profiles in a cell line model for prostate carcinogenesis.
Cancer Res. 61:8143-8149(2001)

CLPUB00698
van Bokhoven A.
Models for prostate cancer. Molecular characterization and critical appraisal of human prostate carcinoma cell lines.
Thesis PhD (2004); Katholieke Universiteit Nijmegen; Nijmegen; Netherlands

PubMed=20164919; DOI=10.1038/nature08768; PMCID=PMC3145113
Bignell G.R., Greenman C.D., Davies H.R., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=21248069; DOI=10.1158/0008-5472.CAN-10-1998; PMCID=PMC3059379
Li Y.-M., Alsagabi M., Fan D.-H., Bova G.S., Tewfik A.H., Dehm S.M.
Intragenic rearrangement and altered RNA splicing of the androgen receptor in a cell-based model of prostate cancer progression.
Cancer Res. 71:2108-2117(2011)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line collections (Providers)DSMZ; ACC-143
ICLC; HTL11006
Millipore; SCC256
Cell line databases/resourcesCLO; CLO_0002022
CLDB; cl7219
cancercelllines; CVCL_1091
Cell_Model_Passport; SIDM00964
Cosmic-CLP; 924105
DepMap; ACH-001453
DSMZCellDive; ACC-143
IGRhCellID; BPH1
LINCS_HMS; 50005
LINCS_LDP; LCL-2095
SKY/M-FISH/CGH; 1510
Anatomy/cell type resourcesBTO; BTO_0001323
Biological sample resourcesBioSample; SAMN03473417
Chemistry resourcesChEMBL-Cells; CHEMBL3308186
ChEMBL-Targets; CHEMBL2366131
GDSC; 924105
PharmacoDB; BPH1_107_2019
PubChem_Cell_line; CVCL_1091
Encyclopedic resourcesWikidata; Q54798059
Experimental variables resourcesEFO; EFO_0022691
Gene expression databasesArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM827571
GEO; GSM1374405
GEO; GSM1669628
Polymorphism and mutation databasesCosmic; 924105
Cosmic; 1995347
IARC_TP53; 27687
Progenetix; CVCL_1091
Proteomic databasesPRIDE; PXD030304
Sequence databasesEGA; EGAS00001000978

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