RBE人肝胆管癌细胞

价 格:¥1800

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-1149

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameRBE
AccessionBTCC-1149
Resource Identification InitiativeTo cite this cell line use: RBE (BTCC-1149)
CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: JFCR45 cancer cell line panel.
Population: Japanese.
Doubling time: 45 hours (PubMed=9358283).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Misspelling: RBA; CelloPub=CLPUB00275.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 5382; IDH1; Simple; p.Arg132Ser (c.394C>A); ClinVar=VCV000375893; Zygosity=Unspecified (PubMed=27231123; DepMap).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Unspecified (DepMap).
DiseaseIntrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
HierarchyChildren:

CVCL_A9CU (RBE-Luc2-tdT)
Sex of cellFemale
Age at sampling64Y
CategoryCancer cell line
STR profileSource(s): CCRID; DepMap; RCB

Markers:
AmelogeninX
CSF1PO12
D2S133817,24
D3S135814,15
D5S81811,12
D7S8208,11
D8S117913,14
D13S3179
D16S53910,11
D18S5113,15
D19S43314,15.2
D21S1129
FGA19,24
Penta D12
Penta E18
TH016
TPOX8
vWA20

Run an STR similarity search on this cell line
Web pageshttps://cell.brc.riken.jp/en/rcb/rbessp-25_announce
Publications

PubMed=9358283; DOI=10.1007/s11626-997-0125-z
Enjoji M., Sakai H., Nawata H., Kajiyama K., Tsuneyoshi M.
Sarcomatous and adenocarcinoma cell lines from the same nodule of cholangiocarcinoma.
In Vitro Cell. Dev. Biol. Anim. 33:681-683(1997)

PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234
Nakatsu N., Yoshida Y., Yamazaki K., Nakamura T., Dan S., Fukui Y., Yamori T.
Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.
Mol. Cancer Ther. 4:399-412(2005)

CLPUB00275
Zach S., Birgin E., Ruckert F.
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442
Saha S.K., Gordan J.D., Kleinstiver B.P., Vu P., Najem M.S., Yeo J.-C., Shi L., Kato Y., Levin R.S., Webber J.T., Damon L.J., Egan R.K., Greninger P., McDermott U., Garnett M.J., Jenkins R.L., Rieger-Christ K.M., Sullivan T.B., Hezel A.F., Liss A.S., Mizukami Y., Goyal L., Ferrone C.R., Zhu A.X., Joung J.K., Shokat K.M., Benes C.H., El-Bardeesy N.
Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.
Cancer Discov. 6:727-739(2016)

PubMed=31077409; DOI=10.1002/hep.30704
Sittithumcharee G., Suppramote O., Vaeteewoottacharn K., Sirisuksakun C., Jamnongsong S., Laphanuwat P., Suntiparpluacha M., Matha A., Chusorn P., Buraphat P., Kakanaporn C., Charngkaew K., Silsirivanit A., Korphaisarn K., Limsrichamrern S., Tripatara P., Pairojkul C., Wongkham S., Sampattavanich S., Okada S., Jirawatnotai S.
Dependency of cholangiocarcinoma on cyclin D-dependent kinase activity.
Hepatology 70:1614-1630(2019)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007
Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y., Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S., Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cross-references
Cell line databases/resourcesCLO; CLO_0050848
CCRID; 1101HUM-PUMC000675
CCRID; 3101HUMTCHu179
Cell_Model_Passport; SIDM01850
DepMap; ACH-001856
Biological sample resourcesBioSample; SAMN03472125
Cell line collections (Providers)CLS; 305019
KCB; KCB 2014049YJ
RCB; RCB1292
Encyclopedic resourcesWikidata; Q54949330
Polymorphism and mutation databasesCosmic; 1187341
Cosmic; 1571785
Cosmic; 2629289

更多>>相关产品

总部地址:北京市怀柔区渤海镇怀沙路536号

关注我们
在线咨询
在线客服
电话咨询
微信客服
返回顶部