U-937 人淋巴瘤细胞

价 格:¥1800

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-1199

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameU-937
SynonymsU937; U 937
AccessionBTCC-1199
Resource Identification InitiativeTo cite this cell line use: U-937 (BTCC-1199)
CommentsGroup: Space-flown cell line (cellonaut).
Problematic cell line: Partially contaminated. Some ATCC stocks were cross-contaminated by K-562 initially (PubMed=7759961). The problem was corrected and subsequent stocks have been confirmed to carry only U-937.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: LL-100 blood cancer cell line panel.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00168.
Population: Caucasian.
Characteristics: Can be induced to differentiate into macrophages by several factors such as phorbol ester (PMA) and 12-O-tetradecanoyl-13-phorbol acetate (TPA).
Doubling time: 95-100 hours (PubMed=178611); ~30-40 hours (DSMZ=ACC-5).
Karyotypic information: Has lost chromosome Y.
Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526).
Omics: Deep antibody staining analysis.
Omics: Deep exome analysis.
Omics: Deep proteome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: Proteome analysis by 2D-DE/MS.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Anecdotal: Have been flown in space on shuttle flight STS-76 and on Shenzhou-8 to study growth and cytoskeletal changes in microgravity (PubMed=10352142; DOI=10.1016/j.actaastro.2013.06.007).
Discontinued: TKG; TKG 0279; probable.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 16063; MLLT10 + HGNC; 15514; PICALM; Name(s)=PICALM-MLLT10, CALM-AF10 (PubMed=8643484; PubMed=25485619).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Gly129fs*51 (c.387_388insCGCC); Zygosity=Hemizygous (PubMed=10966170; DepMap).
  • Mutation; HGNC; 9644; PTPN11; Simple; p.Gly60Arg (c.178G>C); ClinVar=VCV000372590; Zygosity=Heterozygous (DepMap).
  • Mutation; HGNC; 11998; TP53; Simple; c.559+1G>A (p.Val173Trpfs*59); ClinVar=VCV000428908; Zygosity=Homozygous; Note=Splice donor mutation (PubMed=1571549; DepMap).
  • Mutation; HGNC; 12796; WT1; Simple; p.Arg301Ter (c.901C>T) (p.Arg352Ter, c.1054C>T) (p.Arg374Ter, c.1120C>T); ClinVar=VCV000449416; Zygosity=Heterozygous (DepMap).
HLA typingSource: IPD-IMGT/HLA=11507
Class II
HLA-DRDRB1*16:01

Source: PubMed=26589293
Class I
HLA-AA*03:01,03:01
HLA-BB*18:01,51:01
HLA-CC*01:02,07:01
Class II
HLA-DRDRB1*16:01,16:01
Genome ancestrySource: PubMed=30894373

Origin% genome


African0
Native American0
East Asian, North2.39
East Asian, South0
South Asian0
European, North71.54
European, South26.06
DiseaseAdult acute monocytic leukemia (NCIt: C8263)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
HierarchyChildren:



CVCL_3680 (EL 1)CVCL_2082 (JOSK-I)CVCL_8141 (JOSK-K)
CVCL_2083 (JOSK-M)CVCL_8142 (JOSK-S)CVCL_B3XU (MBU-7)
CVCL_B3XV (MBU-8)CVCL_8442 (MOBS-1)CVCL_L107 (PH [Human])
CVCL_9997 (SAML-1)CVCL_6444 (SC [Human contaminated U-937])CVCL_1775 (TUR)
CVCL_2810 (U-937 cl1-14)CVCL_2811 (U-937 cl1-22)CVCL_8765 (U-937 DE-4)
CVCL_U631 (U-937 GTB)CVCL_C8E1 (U-937 INPP5D KO)CVCL_WV56 (U-937 RERC)
CVCL_X000 (U-937-AG)CVCL_WV55 (U-937/CR)CVCL_VG84 (U-M)
CVCL_M769 (U1/HIV-1)CVCL_M770 (U38)CVCL_8927 (U937(CD59+))
CVCL_8932 (U937(CD59-))CVCL_A5BW (U937-ASPI3K)CVCL_2Z95 (U937-DC-SIGN)
CVCL_4V23 (U937/ara-C)CVCL_Y170 (U937/clone21)CVCL_Y171 (U937/clone36)
CVCL_Y172 (U937/clone41)CVCL_Y173 (U937/clone49)CVCL_A5ZK (U937/EVI1)
CVCL_X608 (U937/HIV-2MS)CVCL_Y174 (U937/UK110)CVCL_Y175 (U937/UK711)
CVCL_8466 (YAA)CVCL_8467 (YAP)
Sex of cellMale
Age at sampling37Y
CategoryCancer cell line
STR profileSource(s): AddexBio; ATCC; CCRID; CLS; COG; DSMZ; ECACC; Genomics_Center_BCF_Technion; JCRB; KCLB; PubMed=11416159; PubMed=15637111; PubMed=25877200; PubMed=34707142; RCB

Markers:
AmelogeninX
CSF1PO10,12 (DSMZ; PubMed=15637111)
12 (AddexBio; ATCC; CCRID; CLS; COG; ECACC; Genomics_Center_BCF_Technion; JCRB; KCLB; PubMed=25877200; PubMed=34707142; RCB)
D1S165617.3
D2S44110
D2S133817 (DSMZ)
17,20 (CCRID; CLS; COG; Genomics_Center_BCF_Technion; PubMed=34707142)
D3S135816 (CCRID; CLS; COG; Genomics_Center_BCF_Technion; PubMed=25877200; PubMed=34707142)
16,17 (DSMZ)
D5S81810,12 (PubMed=15637111)
10,12,13 (DSMZ)
12 (AddexBio; ATCC; CCRID; CLS; COG; ECACC; Genomics_Center_BCF_Technion; JCRB; KCLB; PubMed=25877200; PubMed=34707142; RCB)
D7S8209,11
D8S117912,13
D10S124814
D12S39117,18
D13S31710,12
D16S53912
D18S5113,14
D19S43314,16
D21S1127 (DSMZ; PubMed=15637111)
27,29 (CCRID; CLS; COG; Genomics_Center_BCF_Technion; PubMed=25877200; PubMed=34707142)
D22S104517
FGA22,25
Penta D12,13 (CLS; COG; Genomics_Center_BCF_Technion; PubMed=25877200)
13 (DSMZ; PubMed=15637111)
Penta E13
TH016,9.3 (AddexBio; ATCC; CCRID; CLS; COG; DSMZ; ECACC; Genomics_Center_BCF_Technion; JCRB_IFO50038; PubMed=11416159; PubMed=15637111; PubMed=25877200; PubMed=34707142; RCB)
6,10 (JCRB_JCRB9021)
9.3 (KCLB)
TPOX8,11
vWA14,15 (AddexBio; CCRID; CLS; COG; DSMZ; ECACC; Genomics_Center_BCF_Technion; JCRB; PubMed=11416159; PubMed=15637111; PubMed=25877200; RCB)
15 (ATCC; KCLB; PubMed=34707142)

Run an STR similarity search on this cell line
Web pageshttps://en.wikipedia.org/wiki/U937_cells
http://www.cells-talk.com/index.php/page/copelibrary?key=U937
https://www.atcc.org/en/support/technical-support/faqs/growth-and-morphology-of-atcc-item-crl-1593-2
https://www.proteinatlas.org/learn/cellines
https://web.archive.org/web/20201109215324/www.infarktforschung.de/macrophages_cell_lines.html
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/u/cell-lines-detail-315.html
http://www.nibsc.org/Default.aspx?pageid=597&id=0012&theme=default
Publications

DOI=10.1007/978-1-4757-1647-4_13
Biedler J.L.
Chromosome abnormalities in human tumor cells in culture.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.359-394; Springer; New York (1975)

PubMed=178611; DOI=10.1002/ijc.2910170504
Sundstrom C., Nilsson K.
Establishment and characterization of a human histiocytic lymphoma cell line (U-937).
Int. J. Cancer 17:565-577(1976)

PubMed=1083890; DOI=10.1084/jem.143.6.1528
Ralph P., Moore M.A., Nilsson K.
Lysozyme synthesis by established human and murine histiocytic lymphoma cell lines.
J. Exp. Med. 143:1528-1533(1976)

PubMed=6091813; DOI=10.1182/blood.V64.5.1059.1059
Palumbo A., Minowada J., Erikson J., Croce C.M., Rovera G.
Lineage infidelity of a human myelogenous leukemia cell line.
Blood 64:1059-1063(1984)

PubMed=6582512; DOI=10.1073/pnas.81.2.568
Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O.
Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984)

PubMed=2985879; DOI=10.1016/0145-2126(85)90084-0
Drexler H.G., Gaedicke G., Minowada J.
Isoenzyme studies in human leukemia-lymphoma cell lines -- 1 carboxylic esterase.
Leuk. Res. 9:209-229(1985)

PubMed=3159941; DOI=10.1016/0145-2126(85)90134-1
Drexler H.G., Gaedicke G., Minowada J.
Isoenzyme studies in human leukemia-lymphoma cell lines -- III Beta-hexosaminidase (E.C. 3.2.1.30).
Leuk. Res. 9:549-559(1985)

PubMed=3874327; DOI=10.1016/0145-2126(85)90133-x
Drexler H.G., Gaedicke G., Minowada J.
Isoenzyme studies in human leukemia-lymphoma cells lines -- II. Acid phosphatase.
Leuk. Res. 9:537-548(1985)

DOI=10.1159/000415060
Morikawa S., Harada T., Katoh T.
Heterogeneity of cellular origins in human malignant lymphoma cell line derived from histo-monocytic lineage cells.
(In) Cellular, molecular, genetic approaches to immunodiagnosis and immunotherapy. 8th International conference on labeled antibodies, Tokyo, November 1985; Kano K., Mori S., Sugisaki T., Torisu M. (eds.); pp.373-380; Karger; Basel (1988)

PubMed=2140233; DOI=10.1111/j.1440-1827.1990.tb01549.x
Nakano A., Harada T., Morikawa S., Kato Y.
Expression of leukocyte common antigen (CD45) on various human leukemia/lymphoma cell lines.
Acta Pathol. Jpn. 40:107-115(1990)

DOI=10.1007/978-94-011-3550-4_20
Shinohara K., Kong Z.-L., Murakami H.
Characterization of a human derived macrophage-like cell line, U-M.
(In) Animal cell culture and production of biologicals; Sasaki R., Ikura K. (eds.); pp.181-186; Springer; Dordrecht (1991)

PubMed=1913629; DOI=10.1016/0304-3835(91)90051-I
Chang K.S.-S., Liu W.-T., Josephs S.F.
Regulation of cellular trans-activating activities in two different promonocytic leukemia cell lines.
Cancer Lett. 60:75-83(1991)

PubMed=1571549; DOI=10.1182/blood.V79.9.2378.2378
Sugimoto K., Toyoshima H., Sakai R., Miyagawa K., Hagiwara K., Ishikawa F., Takaku F., Yazaki Y., Hirai H.
Frequent mutations in the p53 gene in human myeloid leukemia cell lines.
Blood 79:2378-2383(1992)

PubMed=8300570; DOI=10.1016/S0021-9258(17)41964-8
Rubin E.H., Pantazis P., Bharti A., Toppmeyer D., Giovanella B.C., Kufe D.W.
Identification of a mutant human topoisomerase I with intact catalytic activity and resistance to 9-nitro-camptothecin.
J. Biol. Chem. 269:2433-2439(1994)

PubMed=7759961; DOI=10.1002/jlb.57.5.804
Reid Y.A., McGuire L., O'Neill K., Macy M.L., Chen T.R., McClintock P., Dorotinsky C.S., Hay R.
Cell line cross-contamination of U-937.
J. Leukoc. Biol. 57:804-804(1995)

PubMed=8547074; DOI=10.1111/j.1365-2141.1995.tb05302.x
Siebert R., Willers C.P., Schramm A., Fossa A., Dresen I.M.G., Uppenkamp M., Nowrousian M.R., Seeber S., Opalka B.
Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and lymphoblastic leukaemia cell lines.
Br. J. Haematol. 91:350-354(1995)

PubMed=8558913
Morita S., Tsuchiya S., Fujie H., Itano M., Ohashi Y., Minegishi M., Imaizumi M., Endo M., Takano N., Konno T.
Cell surface c-kit receptors in human leukemia cell lines and pediatric leukemia: selective preservation of c-kit expression on megakaryoblastic cell lines during adaptation to in vitro culture.
Leukemia 10:102-105(1996)

PubMed=8558920
Dirks W.G., Zaborski M., Jager K., Challier C., Shiota M., Quentmeier H., Drexler H.G.
The (2;5)(p23;q35) translocation in cell lines derived from malignant lymphomas: absence of t(2;5) in Hodgkin-analogous cell lines.
Leukemia 10:142-149(1996)

PubMed=8643484; DOI=10.1073/pnas.93.10.4804
Dreyling M.H., Martinez-Climent J.A., Zheng M., Mao J., Rowley J.D., Bohlander S.K.
The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family.
Proc. Natl. Acad. Sci. U.S.A. 93:4804-4809(1996)

PubMed=9371509
Saleem A., Ibrahim N., Patel M., Li X.-G., Gupta E., Mendoza J.T., Pantazis P., Rubin E.H.
Mechanisms of resistance in a human cell line exposed to sequential topoisomerase poisoning.
Cancer Res. 57:5100-5106(1997)

PubMed=9510473; DOI=10.1111/j.1349-7006.1998.tb00476.x
Hosoya N., Hangaishi A., Ogawa S., Miyagawa K., Mitani K., Yazaki Y., Hirai H.
Frameshift mutations of the hMSH6 gene in human leukemia cell lines.
Jpn. J. Cancer Res. 89:33-39(1998)

PubMed=9685479; DOI=10.1093/nar/26.16.3651
Hultdin M., Gronlund E., Norrback K.-F., Eriksson-Lindstrom E., Just T., Roos G.
Telomere analysis by fluorescence in situ hybridization and flow cytometry.
Nucleic Acids Res. 26:3651-3656(1998)

PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x
Takizawa J., Suzuki R., Kuroda H., Utsunomiya A., Kagami Y., Joh T., Aizawa Y., Ueda R., Seto M.
Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia.
Jpn. J. Cancer Res. 89:712-718(1998)

PubMed=10352142; DOI=10.1096/fasebj.13.9001.s23
Hatton J.P., Gaubert F., Lewis M.L., Darsel Y., Ohlmann P., Cazenave J.-P., Schmitt D.
The kinetics of translocation and cellular quantity of protein kinase C in human leukocytes are modified during spaceflight.
FASEB J. 13:S23-S33(1999)

PubMed=10676951; DOI=10.1038/35000501
Alizadeh A.A., Eisen M.B., Davis R.E., Ma C., Lossos I.S., Rosenwald A., Boldrick J.C., Sabet H., Tran T., Yu X., Powell J.I., Yang L.-M., Marti G.E., Moore T., Hudson J. Jr., Lu L.-S., Lewis D.B., Tibshirani R., Sherlock G., Chan W.C., Greiner T.C., Weisenburger D.D., Armitage J.O., Warnke R.A., Levy R., Wilson W., Grever M.R., Byrd J.C., Botstein D., Brown P.O., Staudt L.M.
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling.
Nature 403:503-511(2000)

PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4
Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.
Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines.
Leuk. Res. 24:255-262(2000)

PubMed=10966170; DOI=10.1034/j.1600-0609.2000.90181.x
Aggerholm A., Gronbaek K., Guldberg P., Hokland P.
Mutational analysis of the tumour suppressor gene MMAC1/PTEN in malignant myeloid disorders.
Eur. J. Haematol. 65:109-113(2000)

PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1
Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.
Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000),255-262.
Leuk. Res. 25:275-278(2001)

PubMed=11701946; DOI=10.1159/000048774
Strefford J.C., Foot N.J., Chaplin T., Neat M.J., Oliver R.T.D., Young B.D., Jones L.K.
The characterisation of the lymphoma cell line U937, using comparative genomic hybridisation and multi-plex FISH.
Cytogenet. Cell Genet. 94:9-14(2001)

PubMed=12393283; DOI=10.1016/S0165-4608(02)00565-4
Lee J.-Y., Lee C.-H., Shim S.-H., Seo H.-K., Kyhm J.-H., Cho S., Cho Y.-H.
Molecular cytogenetic analysis of the monoblastic cell line U937 karyotype clarification by G-banding, whole chromosome painting, microdissection and reverse painting, and comparative genomic hybridization.
Cancer Genet. Cytogenet. 137:124-132(2002)

PubMed=15637111; DOI=10.1096/fj.04-3062fje
Parson W., Kirchebner R., Muhlmann R., Renner K., Kofler A., Schmidt S., Kofler R.
Cancer cell line identification by short tandem repeat profiling: power and limitations.
FASEB J. 19:434-436(2005)

PubMed=15843827; DOI=10.1038/sj.leu.2403749
Andersson A., Eden P., Lindgren D., Nilsson J., Lassen C., Heldrup J., Fontes M., Borg A., Mitelman F., Johansson B., Hoglund M., Fioretos T.
Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations.
Leukemia 19:1042-1050(2005)

PubMed=16311011; DOI=10.1016/j.tiv.2005.10.012
Ashikaga T., Yoshida Y., Hirota M., Yoneyama K., Itagaki H., Sakaguchi H., Miyazawa M., Ito Y., Suzuki H., Toyoda H.
Development of an in vitro skin sensitization test using human cell lines: the human Cell Line Activation Test (h-CLAT). I. Optimization of the h-CLAT protocol.
Toxicol. In Vitro 20:767-773(2006)

PubMed=16337770; DOI=10.1016/j.tiv.2005.10.014
Sakaguchi H., Ashikaga T., Miyazawa M., Yoshida Y., Ito Y., Yoneyama K., Hirota M., Itagaki H., Toyoda H., Suzuki H.
Development of an in vitro skin sensitization test using human cell lines; human Cell Line Activation Test (h-CLAT). II. An inter-laboratory study of the h-CLAT.
Toxicol. In Vitro 20:774-784(2006)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=20801507; DOI=10.1016/j.leukres.2010.07.040
Minafra L., Di Cara G., Albanese N.N., Cancemi P.
Proteomic differentiation pattern in the U937 cell line.
Leuk. Res. 35:226-236(2011)

PubMed=21269460; DOI=10.1186/1752-0509-5-17
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol. 5:17.1-17.13(2011)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

DOI=10.1016/j.actaastro.2013.06.007
Paulsen K., Tauber S., Golz N., Simmet D.M., Engeli S., Birlem M., Dumrese C., Karer A., Hunziker S., Biskup J., Konopasek S., Suh D., Breuer-Hurlimann E., Signer C., Wang A., Sang C., Grote K.-H., Zhuang F.-Y., Ullrich O.
Severe disruption of the cytoskeleton and immunologically relevant surface molecules in a human macrophageal cell line in microgravity -- results of an in vitro experiment on board of the Shenzhou-8 space mission.
Acta Astronaut. 94:277-292(2013)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=29787063; DOI=10.1007/978-3-319-16104-4_14
Chanput W., Peters V., Wichers H.
THP-1 and U937 cells.
(In) The impact of food bioactives on health. In vitro and ex vivo models; Verhoeckx K., Cotter P., Lopez-Exposito I., Kleiveland C., Lea T., Mackie A., Requena T., Swiatecka D., Wichers H. (eds.); pp.147-159; Springer; Cham (2015)

PubMed=30285677; DOI=10.1186/s12885-018-4840-5
Tan K.-T., Ding L.-W., Sun Q.-Y., Lao Z.-T., Chien W., Ren X., Xiao J.-F., Loh X.-Y., Xu L., Lill M., Mayakonda A., Lin D.-C., Yang H., Koeffler H.P.
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
BMC Cancer 18:940.1-940.13(2018)

PubMed=30629668; DOI=10.1371/journal.pone.0210404
Uphoff C.C., Pommerenke C., Denkmann S.A., Drexler H.G.
Screening human cell lines for viral infections applying RNA-Seq data analysis.
PLoS ONE 14:E0210404-E0210404(2019)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x
Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M., MacLeod R.A.F., Nagel S., Steube K., Uphoff C.C., Drexler H.G.
The LL-100 panel: 100 cell lines for blood cancer studies.
Sci. Rep. 9:8218-8218(2019)

PubMed=31978347; DOI=10.1016/j.cell.2019.12.023
Nusinow D.P., Szpyt J., Ghandi M., Rose C.M., McDonald E.R. III, Kalocsay M., Jane-Valbuena J., Gelfand E.T., Schweppe D.K., Jedrychowski M.P., Golji J., Porter D.A., Rejtar T., Wang Y.K., Kryukov G.V., Stegmeier F., Erickson B.K., Garraway L.A., Sellers W.R., Gygi S.P.
Quantitative proteomics of the Cancer Cell Line Encyclopedia.
Cell 180:387-402.e16(2020)

PubMed=33317567; DOI=10.1186/s13039-020-00517-y
MacKinnon R.N., Peverall J., Campbell L.J., Wall M.
Detailed molecular cytogenetic characterisation of the myeloid cell line U937 reveals the fate of homologous chromosomes and shows that centromere capture is a feature of genome instability.
Mol. Cytogenet. 13:50.1-50.14(2020)

PubMed=34707142; DOI=10.1038/s41598-021-00623-w
Maher M., Diesch J., Le Pannerer M.-M., Cabezon M., Mallo M., Vergara S., Mendez Lopez A., Mesa Tudel A., Sole F., Sorigue M., Zamora L., Granada I., Buschbeck M.
Divergent leukaemia subclones as cellular models for testing vulnerabilities associated with gains in chromosomes 7, 8 or 18.
Sci. Rep. 11:21145-21145(2021)

Cross-references
Cell line databases/resourcesCLO; CLO_0009450
CLO; CLO_0009465
MCCL; MCC:0000470
CLDB; cl4597
CLDB; cl4599
CLDB; cl4600
CLDB; cl4601
CLDB; cl4602
CLDB; cl4603
CLDB; cl4604
CLDB; cl4605
CLDB; cl4606
CLDB; cl4608
CCRID; 1101HUM-PUMC000059
CCRID; 3101HUMTCHu159
CCRID; 4201HUM-CCTCC00080
Cell_Model_Passport; SIDM01195
DepMap; ACH-000406
DSMZCellDive; ACC-5
IPD-IMGT/HLA; 11507
LINCS_HMS; 50869
LINCS_LDP; LCL-1125
Lonza; 135
TOKU-E; 3382
Anatomy/cell type resourcesBTO; BTO:0001412
Biological sample resourcesBioSample; SAMN03472409
BioSample; SAMN03473173
BioSample; SAMN03473567
BioSample; SAMN10988180
Cell line collections (Providers)AddexBio; C0003005/72
ATCC; CRL-1593 - Discontinued
ATCC; CRL-1593.2
BCRC; 60435
BCRJ; 0242
CCTCC; GDC0080
CLS; 300368
DSMZ; ACC-5
ECACC; 85011440
ICLC; HTL94002
IZSLER; BS TCL 73
JCRB; IFO50038
JCRB; JCRB9021
KCB; KCB 200676YJ
KCLB; 21593.1
NCBI_Iran; C130
RCB; RCB1978 - Discontinued
TKG; TKG 0279
Chemistry resourcesChEMBL-Cells; CHEMBL3308006
ChEMBL-Targets; CHEMBL612794
PharmacoDB; U937_1624_2019
PubChem_Cell_line; CVCL_0007
Encyclopedic resourcesWikidata; Q7863610
Experimental variables resourcesEFO; EFO_0001257

更多>>相关产品

总部地址:北京市怀柔区渤海镇怀沙路536号

关注我们
在线咨询
在线客服
电话咨询
微信客服
返回顶部