Cell line name | NK-92MI | ||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Synonyms | NK-92 MI; NK-92 mi; NK92-MI; NK92MI; NK-92 transfected with MFG-hIL2 | ||||||||||||||||||||||||||||||||
Accession | BTCC-1217 | ||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: NK-92MI (BTCC-1217) | ||||||||||||||||||||||||||||||||
Comments | Group: Patented cell line. Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-6671. Characteristics: No longer dependent on IL2. Microsatellite instability: Stable (MSS) (Sanger). Transfected with: HGNC; 6001; IL2. Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: DNA methylation analysis. Caution: This cell line is exclusively owned and controlled by NantKwest, Inc. NantKwest and its affiliate, Brink Biologics, Inc. are the sole authorized distributors for both commercial and non-commercial research requestors. There are no other authorized commercial and non-commercial suppliers of NK-92MI. Contact NantKwest and Brink Biologics for information concerning current inventory and cell line use and support. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: Natural killer cell; CL=CL_0000623. | ||||||||||||||||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
| ||||||||||||||||||||||||||||||||
Disease | Natural killer cell lymphoblastic leukemia/lymphoma (NCIt: C82217) | ||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||
Hierarchy | Parent: CVCL_2142 (NK-92) Children:
| ||||||||||||||||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||||||||||||||||
Age at sampling | 50Y | ||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||
STR profile | Source(s): ATCC; CCRID; Cosmic-CLP Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||
Publications | PubMed=10365666; DOI=10.1089/10430349950018030 Patent=US8034332 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010 | ||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0008178 CCRID; 1102HUM-NIFDC00065 Cell_Model_Passport; SIDM01201 Cosmic-CLP; 1330981 DepMap; ACH-002289 LINCS_LDP; LCL-1127 | ||||||||||||||||||||||||||||||||
Cell line collections (Providers) | ATCC; CRL-2408 BCRC; 60438 - Discontinued KCB; KCB 200677YJ | ||||||||||||||||||||||||||||||||
Chemistry resources | GDSC; 1330981 PharmacoDB; NK92MI_1160_2019 | ||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54930658 | ||||||||||||||||||||||||||||||||
Gene expression databases | GEO; GSM1670278 | ||||||||||||||||||||||||||||||||
Proteomic databases | PRIDE; PXD030304 |