BEWO人胎盘绒膜癌细胞

价 格:¥1800

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-1232

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameBeWo
SynonymsBEWO; Be Wo; Be-Wo
AccessionBTCC-1232
Resource Identification InitiativeTo cite this cell line use: BeWo (BTCC-1232)
CommentsCharacteristics: Cells were initially transplanted to the cheek pouch of a hamster and maintained by serial passage for 8 years prior to the establishment of the cell line.
Doubling time: ~30 hours (DSMZ=ACC-458).
Karyotypic information: Near triploid karyotype (PubMed=33096371).
Omics: Deep antibody staining analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Fetal brain; UBERON=UBERON_0006237.
HLA typingSource: IPD-IMGT/HLA=10312
Class I
HLA-CC*04:01:01:01,07:01
DiseaseGestational choriocarcinoma (NCIt: C4646)
Gestational choriocarcinoma (ORDO: Orphanet_99926)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
HierarchyChildren:



CVCL_LB82 (BeWo b24)CVCL_LB83 (BeWo b30)CVCL_XF88 (Bewo31)
CVCL_R702 (Hs 630.T)

Originate from same individualCVCL_0363 ! JEG-3
Sex of cellMale
Age at samplingFetus
CategoryCancer cell line
STR profileSource(s): AddexBio; ATCC; CCRID; CLS; DSMZ; ECACC; KCLB; PubMed=33810901; RCB; TKG

Markers:
AmelogeninX,Y
CSF1PO11,12
D1S165614,16
D2S44114
D2S133821,24
D3S135815
D5S81810,11
D7S82010,12
D8S117912
D10S124813,15
D12S39117,24
D13S3179,11
D16S53913,14
D18S5114,16
D19S43313,15
D21S1130
D22S104515
FGA22,23 (KCLB)
22,23,24 (CCRID; CLS; DSMZ; PubMed=33810901)
Penta D9,12
Penta E8,12
SE3315,25.2
TH019,9.3
TPOX8
vWA16

Run an STR similarity search on this cell line
Web pageshttps://www.proteinatlas.org/learn/cellines
http://www2.kumc.edu/soalab/LabLinks/recipes/bewo.htm
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/b/cell-lines-detail-163.html
Publications

PubMed=14207855; DOI=10.1093/jnci/33.3.441
Dawe C.J., Banfield W.G. II, Morgan W.D., Slatick M.S., Ollendorf-Curth H.
Growth in continuous culture, and in hamsters, of cells from a neoplasm associated with acanthosis nigricans.
J. Natl. Cancer Inst. 33:441-456(1964)

PubMed=4299001
Pattillo R.A., Gey G.O.
The establishment of a cell line of human hormone-synthesizing trophoblastic cells in vitro.
Cancer Res. 28:1231-1236(1968)

PubMed=5753554; DOI=10.1126/science.159.3822.1467
Pattillo R.A., Gey G.O., Delfs E., Mattingly R.F.
Human hormone production in vitro.
Science 159:1467-1469(1968)

PubMed=6174649
Sekiya S., Kawata M., Inaba N., Takamizawa H.
Studies on marker substances in cell lines derived from various human gynecologic tumors.
Nihon Sanka Fujinka Gakkai Zasshi 34:37-42(1982)

PubMed=7153601
Sasaki S., Katayama P.K., Roesler M., Pattillo R.A., Mattingly R.F., Ohkawa K.
Cytogenetic analysis of choriocarcinoma cell lines.
Nihon Sanka Fujinka Gakkai Zasshi 34:2253-2256(1982)

PubMed=6682628; DOI=10.1016/0002-9378(83)90927-4
Sekiya S., Kaiho T., Shirotake S., Iwasawa H., Takeda B., Takamizawa H.
Effect of methotrexate on the growth and human chorionic gonadotropin secretion of human choriocarcinoma cell lines in vitro.
Am. J. Obstet. Gynecol. 146:57-64(1983)

PubMed=4038916; DOI=10.1016/0165-4608(85)90052-4
Sheppard D.M., Fisher R.A., Lawler S.D.
Karyotypic analysis and chromosome polymorphisms in four choriocarcinoma cell lines.
Cancer Genet. Cytogenet. 16:251-258(1985)

PubMed=2878840; DOI=10.1016/0020-7292(86)90088-3
Yamashita K., Nakamura T., Shimizu T., Katagiri M., Ikeda H.
Expression of HLA class I and class II antigens in human choriocarcinoma cell lines.
Int. J. Gynecol. Obstet. 24:301-307(1986)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=2720636; DOI=10.1016/0165-4608(89)90664-X
Surti U., Habibian R.
Chromosomal rearrangement in choriocarcinoma cell lines.
Cancer Genet. Cytogenet. 38:229-240(1989)

PubMed=7937597; DOI=10.1016/0143-4004(94)90008-6
Grummer R., Hohn H.-P., Mareel M.M., Denker H.-W.
Adhesion and invasion of three human choriocarcinoma cell lines into human endometrium in a three-dimensional organ culture system.
Placenta 15:411-429(1994)

PubMed=7819056; DOI=10.1038/bjc.1995.3
Yaginuma Y., Yamashita T., Takuma N., Katayama H., Ishikawa M.
Analysis of the p53 gene in human choriocarcinoma cell lines.
Br. J. Cancer 71:9-12(1995)

DOI=10.1007/0-306-46861-1_8
Ganapathy V., Prasad P.D., Leibach F.H.
Choriocarcinoma.
(In) Human cell culture. Vol. 2. Cancer Cell Lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.141-147; Kluwer Academic Publishers; New York (1999)

PubMed=11897413; DOI=10.1016/S0378-5173(01)00929-2
Ampasavate C., Chandorkar G.A., Vande Velde D.G., Stobaugh J.F., Audus K.L.
Transport and metabolism of opioid peptides across BeWo cells, an in vitro model of the placental barrier.
Int. J. Pharm. 233:85-98(2002)

PubMed=16797695; DOI=10.1016/j.placenta.2006.05.001
Burleigh D.W., Kendziorski C.M., Choi Y.J., Grindle K.M., Grendell R.L., Magness R.R., Golos T.G.
Microarray analysis of BeWo and JEG3 trophoblast cell lines: identification of differentially expressed transcripts.
Placenta 28:383-389(2007)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=28161053; DOI=10.1016/j.placenta.2016.12.007
Abou-Kheir W., Barrak J., Hadadeh O., Daoud G.
HTR-8/SVneo cell line contains a mixed population of cells.
Placenta 50:1-7(2017)

PubMed=32178868; DOI=10.1016/j.bbrc.2020.03.031
Li Z.-S., Kurosawa O., Iwata H.
A comparative study of key physiological stem cell parameters between three human trophoblast cell lines.
Biochem. Biophys. Res. Commun. 525:1038-1045(2020)

PubMed=33096371; DOI=10.1016/j.placenta.2020.10.011
Weber M., Weise A., Vasheghani F., Gohner C., Fitzgerald J.S., Liehr T., Markert U.R.
Cytogenomics of six human trophoblastic cell lines.
Placenta 103:72-75(2021)

PubMed=33810901; DOI=10.1016/j.placenta.2021.02.022
Pastuschek J., Nonn O., Gutierrez-Samudio R.N., Murrieta-Coxca J.M., Muller J., Sanft J., Huppertz B., Markert U.R., Groten T., Morales-Prieto D.M.
Molecular characteristics of established trophoblast-derived cell lines.
Placenta 108:122-133(2021)

Cross-references
Cell line databases/resourcesCLO; CLO_0001934
CLO; CLO_0001935
CLO; CLO_0050014
CLDB; cl415
CLDB; cl416
CCRID; 1101HUM-PUMC000156
CCRID; 4201HUM-CCTCC00072
Cell_Model_Passport; SIDM00692
DSMZCellDive; ACC-458
IGRhCellID; BeWo
IPD-IMGT/HLA; 10312
LINCS_LDP; LCL-1293
Lonza; 1449
TOKU-E; 661
Anatomy/cell type resourcesBTO; BTO:0000798
Biological sample resourcesBioSample; SAMN01821537
BioSample; SAMN01821617
BioSample; SAMN03471293
Cell line collections (Providers)AddexBio; C0030001/4905
ATCC; CCL-98
BCRC; 60073
BCRJ; 0048
CCTCC; GDC0072
CLS; 300123
DSMZ; ACC-458
ECACC; 86082803
IZSLER; BS TCL 3
JCRB; JCRB9111
KCLB; 10098
RCB; RCB1644
RCB; RCB3678
TKG; TKG 0567
Chemistry resourcesChEMBL-Cells; CHEMBL3308359
ChEMBL-Targets; CHEMBL614525
PubChem_Cell_line; CVCL_0044
Encyclopedic resourcesWikidata; Q54796111
Experimental variables resourcesEFO; EFO_0002050

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