RWPE-1人前列腺正常细胞(STR鉴定正确)

价 格:¥3000

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-1271

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameRWPE-1
SynonymsRWPE1
AccessionBTCC-1271
Resource Identification InitiativeTo cite this cell line use: RWPE-1 (BTCC-1271)
CommentsGroup: Patented cell line.
Part of: ENCODE project common cell types; tier 3.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11609.
Population: Caucasian.
Doubling time: ~22 hours (PBCF).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
HierarchyChildren:



CVCL_4794 (CTPE)CVCL_3792 (RWPE-2)CVCL_K282 (WPE-int)
CVCL_K283 (WPE-stem)CVCL_3810 (WPE1-NA22)CVCL_3811 (WPE1-NB11)
CVCL_3812 (WPE1-NB14)CVCL_3813 (WPE1-NB26)
Originate from same individualCVCL_3814 ! WPMY-1
Sex of cellMale
Age at sampling54Y
CategoryTransformed cell line
STR profileSource(s): ATCC; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO13
D3S135815,16
D5S81812,15
D7S82010,11
D8S117910,14
D13S3178,14
D16S5399,11
D18S5114,16
D21S1129,31
FGA24,25
Penta D10,13
Penta E5,12
TH018,9.3
TPOX8,11
vWA14,18

Run an STR similarity search on this cell line
Web pageshttps://www.synapse.org/#!Synapse:syn31544576
http://genome.ucsc.edu/ENCODE/protocols/cell/human/RWPE_Crawford_protocol.pdf
Publications

PubMed=8977636; DOI=10.1002/(SICI)1097-0045(199612)29:6<386::aid-pros7>3.0.CO;2-6
Webber M.M., Bello D., Quader S.T.A.
Immortalized and tumorigenic adult human prostatic epithelial cell lines: characteristics and applications. Part I. Cell markers and immortalized nontumorigenic cell lines.
Prostate 29:386-394(1996)

PubMed=9214605; DOI=10.1093/carcin/18.6.1215
Bello D., Webber M.M., Kleinman H.K., Wartinger D.D., Rhim J.S.
Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18.
Carcinogenesis 18:1215-1223(1997)

PubMed=9214606; DOI=10.1093/carcin/18.6.1225
Webber M.M., Bello D., Kleinman H.K., Hoffman M.P.
Acinar differentiation by non-malignant immortalized human prostatic epithelial cells and its loss by malignant cells.
Carcinogenesis 18:1225-1231(1997)

Patent=US6255058
Webber M.M., Rhim J.S.
Immortalized and malignant human prostatic cell lines.
Patent number US6255058, 03-Jul-2001

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=22275356; DOI=10.1074/jbc.M111.302547
Lynch T.P., Ferrer C.M., Jackson S.R., Shahriari K.S., Vosseller K., Reginato M.J.
Critical role of O-linked beta-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis.
J. Biol. Chem. 287:11070-11081(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30305041; DOI=10.1186/s12885-018-4848-x
Jividen K., Kedzierska K.Z., Yang C.-S., Szlachta K., Ratan A., Paschal B.M.
Genomic analysis of DNA repair genes and androgen signaling in prostate cancer.
BMC Cancer 18:960.1-960.20(2018)

PubMed=30787054; DOI=10.1158/1055-9965.EPI-18-1132
Hooker S.E. Jr., Woods-Burnham L., Bathina M., Lloyd S.M., Gorjala P., Mitra R., Nonn L., Kimbro K.S., Kittles R.
Genetic ancestry analysis reveals misclassification of commonly used cancer cell lines.
Cancer Epidemiol. Biomarkers Prev. 28:1003-1009(2019)

Cross-references
Cell line databases/resourcesCLO; CLO_0008905
CCRID; 3101HUMGNHu37
CCRID; 3101HUMSCSP5025
CCRID; 4201HUM-CCTCC00178
Cell_Model_Passport; SIDM00020
IGRhCellID; RWPE1
Lonza; 870
Anatomy/cell type resourcesBTO; BTO:0003709
Biological sample resourcesBioSample; SAMN03470832
BioSample; SAMN05292437
BioSample; SAMN07709991
BioSample; SAMN07709992
BioSample; SAMN07709993
BioSample; SAMN07709994
BioSample; SAMN07709995
BioSample; SAMN07709996
BioSample; SAMN07709997
ENCODE; ENCBS124FCL
ENCODE; ENCBS192LWI
ENCODE; ENCBS263AAA
ENCODE; ENCBS875FPF
Cell line collections (Providers)ATCC; CRL-11609
BCRJ; 0389
CCTCC; GDC0178
Chemistry resourcesChEMBL-Cells; CHEMBL4295468
ChEMBL-Targets; CHEMBL4296492
PharmacoDB; RWPE1_1336_2019
PubChem_Cell_line; CVCL_3791
Encyclopedic resourcesWikidata; Q54951497
Experimental variables resourcesEFO; EFO_0002323
Gene expression databasesArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-3610
GEO; GSM827387
GEO; GSM1008595
GEO; GSM1374860
GEO; GSM1670396
Polymorphism and mutation databasesProgenetix; CVCL_3791
Sequence databasesEGA; EGAS00001000978

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