M-07e人巨核细胞白血病细胞

价 格:¥2400

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-1317

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameM-07e
SynonymsM-07E; M-O7e; M07-e; M07e; Mo7e; MO7e; M07E; MO7E
AccessionBTCC-1317
Resource Identification InitiativeTo cite this cell line use: M-07e (BTCC-1317)
CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: LL-100 blood cancer cell line panel.
Doubling time: 46 +- 12 hours (PubMed=9096695); ~40 hours (DSMZ=ACC-104).
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; 31677; ANO7 + HGNC; 17887; DHDH; Name(s)=ANO7-DHDH (PubMed=31160637).
  • Gene fusion; HGNC; 1537; CBFA2T3 + HGNC; 29450; GLIS2; Name(s)=CBFA2T3-GLIS2, ETO2-GLIS2 (PubMed=28109323).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (DepMap).
HLA typingSource: DSMZCellDive=ACC-104
Class I
HLA-AA*24:02:01,66:01:01
HLA-BB*13:02:01,49:01:01
HLA-CC*06:02:01;07:01:01
Genome ancestrySource: PubMed=30894373

Origin% genome


African8.96
Native American0
East Asian, North0.92
East Asian, South0
South Asian3.01
European, North45.47
European, South41.63
DiseaseChildhood acute megakaryoblastic leukemia (NCIt: C7972)
Acute megakaryoblastic leukemia (ORDO: Orphanet_518)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
HierarchyParent: CVCL_D630 (M-07)
Children:

CVCL_RM07 (M-07e/TPO)
Sex of cellFemale
Age at sampling6M
CategoryCancer cell line
STR profileSource(s): CCRID; DSMZ

Markers:
AmelogeninX
CSF1PO9,10
D2S133819,25
D3S135816,19
D5S81811
D7S82011
D8S117913 (DSMZ)
13,16 (CCRID)
D13S31710,11
D16S53911
D18S5115,20
D19S43314,15
D21S1130,32.2
FGA18,22
Penta D9
Penta E12,14
TH016,8
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Web pageshttp://www.cells-talk.com/index.php/page/copelibrary?key=MO7E
Publications

PubMed=2273055; DOI=10.1002/jcp.1041450310
Avanzi G.C., Brizzi M.F., Giannotti J., Ciarletta A., Yang Y.C., Pegoraro L., Clark S.C.
M-07e human leukemic factor-dependent cell line provides a rapid and sensitive bioassay for the human cytokines GM-CSF and IL-3.
J. Cell. Physiol. 145:458-464(1990)

PubMed=9096695; DOI=10.1038/sj.leu.2400621
Drexler H.G., Zaborski M., Quentmeier H.
Thrombopoietin supports the continuous growth of cytokine-dependent human leukemia cell lines.
Leukemia 11:541-551(1997)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=11414198; DOI=10.1007/s004320000207
Lahm H., Andre S., Hoeflich A., Fischer J.R., Sordat B., Kaltner H., Wolf E., Gabius H.J.
Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures.
J. Cancer Res. Clin. Oncol. 127:375-386(2001)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=28109323; DOI=10.1186/s13045-017-0396-0
Masetti R., Bertuccio S.N., Astolfi A., Chiarini F., Lonetti A., Indio V., De Luca M., Bandini J., Serravalle S., Franzoni M., Pigazzi M., Martelli A.M., Basso G., Locatelli F., Pession A.
Hh/Gli antagonist in acute myeloid leukemia with CBFA2T3-GLIS2 fusion gene.
J. Hematol. Oncol. 10:26.1-26.5(2017)

PubMed=30285677; DOI=10.1186/s12885-018-4840-5
Tan K.-T., Ding L.-W., Sun Q.-Y., Lao Z.-T., Chien W., Ren X., Xiao J.-F., Loh X.-Y., Xu L., Lill M., Mayakonda A., Lin D.-C., Yang H., Koeffler H.P.
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
BMC Cancer 18:940.1-940.13(2018)

PubMed=30629668; DOI=10.1371/journal.pone.0210404
Uphoff C.C., Pommerenke C., Denkmann S.A., Drexler H.G.
Screening human cell lines for viral infections applying RNA-Seq data analysis.
PLoS ONE 14:E0210404-E0210404(2019)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x
Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M., MacLeod R.A.F., Nagel S., Steube K., Uphoff C.C., Drexler H.G.
The LL-100 panel: 100 cell lines for blood cancer studies.
Sci. Rep. 9:8218-8218(2019)

Cross-references
Cell line databases/resourcesCLO; CLO_0007447
CLDB; cl3281
CLDB; cl7156
CCRID; 1101HUM-PUMC000112
Cell_Model_Passport; SIDM01640
DepMap; ACH-000602
DSMZCellDive; ACC-104
Lonza; 485
Anatomy/cell type resourcesBTO; BTO:0005248
Biological sample resourcesBioSample; SAMN03473408
BioSample; SAMN10988568
Cell line collections (Providers)CLS; 305105
DSMZ; ACC-104
ICLC; HTL04002
NCBI_Iran; C621
Chemistry resourcesPharmacoDB; M07e_875_2019
Encyclopedic resourcesWikidata; Q54903379

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