92-1人葡萄膜黑色素瘤细胞(STR鉴定正确)

价 格:¥3000

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-1330

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line name92-1 [Human uveal melanoma]
Synonyms92_1; 92.1; 921
AccessionBTCC-1330
Resource Identification InitiativeTo cite this cell line use: 92-1 [Human uveal melanoma] (BTCC-1330)
CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: 58 hours (PubMed=7622289); 38 hours (PubMed=24994677).
Omics: Deep quantitative proteome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.
Sequence variations
HLA typingSource: PubMed=28018010
Class I
HLA-AA*02:01,03:01
HLA-BB*44:02,51:01
HLA-CC*05:01,14:02
DiseaseUveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
HierarchyChildren:


CVCL_C4PP (92.1-A)CVCL_C4PQ (92.1-B)
Originate from same individualCVCL_C300 ! 92-2
Sex of cellFemale
Age at sampling76Y
CategoryCancer cell line
STR profileSource(s): DepMap; ECACC; ESTDAB; PubMed=22236444; PubMed=24994677; PubMed=28018010

Markers:
AmelogeninX
CSF1PO10,11
D3S135814,15
D5S8189,11 (DepMap; ECACC; PubMed=22236444; PubMed=24994677)
12,13 (ESTDAB)
D7S82010,11 (DepMap; ECACC; PubMed=22236444; PubMed=24994677)
11 (ESTDAB)
D8S117915
D13S31710,11 (ESTDAB; PubMed=24994677)
11,12 (DepMap; ECACC; PubMed=22236444)
D16S53911,12 (PubMed=22236444; PubMed=24994677)
12 (DepMap; ECACC)
D18S5112,13
D21S1130
FGA21,23
Penta D9,11
Penta E12,14
TH019,9.3
TPOX8,9
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=7622289; DOI=10.1002/ijc.2910620208
De Waard-Siebinga I., Blom D.-J.R., Griffioen M., Schrier P.I., Hoogendoorn E., Beverstock G.C., Danen E.H.J., Jager M.J.
Establishment and characterization of an uveal-melanoma cell line.
Int. J. Cancer 62:155-161(1995)

PubMed=15714118; DOI=10.1097/00008390-200502000-00006
Lopez-Velasco R., Morilla-Grasa A., Saornil-Alvarez M.A., Ordonez J.L., Blanco G., Rabano G., Fernandez N., Almaraz A.
Efficacy of five human melanocytic cell lines in experimental rabbit choroidal melanoma.
Melanoma Res. 15:29-37(2005)

PubMed=16772116; DOI=10.1016/j.cancergencyto.2005.11.016
White J.S., Becker R.L., McLean I.W., Director-Myska A.E., Nath J.
Molecular cytogenetic evaluation of 10 uveal melanoma cell lines.
Cancer Genet. Cytogenet. 168:11-21(2006)

PubMed=17487557; DOI=10.1007/s10585-007-9072-z
Marshall J.-C., Nantel A., Blanco P., Ash J., Cruess S.R., Burnier M.N. Jr.
Transcriptional profiling of human uveal melanoma from cell lines to intraocular tumors to metastasis.
Clin. Exp. Metastasis 24:353-362(2007)

PubMed=19340423; DOI=10.1007/s00262-009-0701-z
Mendez R., Aptsiauri N., Del Campo A., Maleno I., Cabrera T., Ruiz-Cabello F., Garrido F., Garcia-Lora A.
HLA and melanoma: multiple alterations in HLA class I and II expression in human melanoma cell lines from ESTDAB cell bank.
Cancer Immunol. Immunother. 58:1507-1515(2009)

PubMed=22236444; DOI=10.1111/j.1755-148X.2012.00971.x
Griewank K.G., Yu X., Khalili J., Sozen M.M., Stempke-Hale K., Bernatchez C., Wardell S., Bastian B.C., Woodman S.E.
Genetic and molecular characterization of uveal melanoma cell lines.
Pigment Cell Melanoma Res. 25:182-187(2012)

PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676
Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V., Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma.
Mol. Cancer Ther. 11:888-897(2012)

PubMed=23849826; DOI=10.1016/j.ejca.2013.06.011
Amaro A., Mirisola V., Angelini G., Musso A., Tosetti F.I., Esposito A.I., Perri P., Lanza F.B., Nasciuti F., Mosci C., Puzone R., Salvi S., Truini M., Poggi A., Pfeffer U.
Evidence of epidermal growth factor receptor expression in uveal melanoma: inhibition of epidermal growth factor-mediated signalling by Gefitinib and Cetuximab triggered antibody-dependent cellular cytotoxicity.
Eur. J. Cancer 49:3353-3365(2013)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L., Borg A., Pawelec G., Guldberg P.
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

PubMed=24994677; DOI=10.1016/j.molonc.2014.06.004
Amirouchene-Angelozzi N., Nemati F., Gentien D., Nicolas A., Dumont A., Carita G., Camonis J., Desjardins L., Cassoux N., Piperno-Neumann S., Mariani P., Sastre X., Decaudin D., Roman-Roman S.
Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target.
Mol. Oncol. 8:1508-1520(2014)

PubMed=28018010
Jager M.J., Bermudez Magner J.A., Ksander B.R., Dubovy S.R.
Uveal melanoma cell lines: where do they come from? (an American Ophthalmological Society thesis).
Trans. Am. Ophthalmol. Soc. 114:T5-T5(2016)

PubMed=32430489; DOI=10.1158/1535-7163.MCT-19-1016
Teh J.L.F., Purwin T.J., Han A., Chua V., Patel P., Baqai U., Liao C., Bechtel N., Sato T., Davies M.A., Aguirre-Ghiso J.A., Aplin A.E.
Metabolic adaptations to MEK and CDK4/6 cotargeting in uveal melanoma.
Mol. Cancer Ther. 19:1719-1726(2020)

PubMed=36164296; DOI=10.1016/j.dib.2022.108592
Fei X.-F., Xie X.-T., Ji X.-Y., Tian H.-Y., Sun F., Jiang D.-Y., Wang Z.-M., Huang Q.
Quantitative proteomic dataset of whole protein in three melanoma samples of 92.1, 92.1-A and 92.1-B.
Data Brief 45:108592.1-108592.7(2022)

Cross-references
Cell line databases/resourcesCLDB; cl7221
DepMap; ACH-001441
ESTDAB; ESTDAB-127
Cell line collections (Providers)ECACC; 13012458
ICLC; HTL12001
Encyclopedic resourcesWikidata; Q54605663
Gene expression databasesGEO; GSM276761

更多>>相关产品

总部地址:北京市怀柔区渤海镇怀沙路536号

关注我们
在线咨询
在线客服
电话咨询
微信客服
返回顶部