293(HEK-293)人胚肾细胞

价 格:¥***

期 货:1周左右

保藏中心:BTCC

资源编号:BTCC-1002

产地:中国

套 餐:

细胞会员价 细胞非会员价 完全培养基500ml(仅供会员) 南美特级胎牛血清500ml(仅供会员)

详细资料说明书下载质检报告(COA)

Cell line nameHEK293
SynonymsHek293; HEK-293; HEK/293; HEK 293; HEK;293; 293; 293 HEK; 293 Ad5; Graham 293; Graham-293; Human Embryonic Kidney 293
AccessionBTCC-1002
Resource Identification InitiativeTo cite this cell line use: HEK293 (BTCC-1002)
CommentsGroup: Vaccine production cell line.
Part of: ENCODE project common cell types; tier 3.
Part of: MD Anderson Cell Lines Project.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-4488.
Biotechnology: Used for the production of the Gamaleya SARS-CoV-2 (COVID-19) vaccine (Trade name: Gam-COVID-Vac; also known as Sputnik V) (DrugBank=DB15848). Caution: we are not convinced that the cell line used for the production of this vaccine is a "plain vanilla" HEK293, it is probably an engineered derivative, but there is currently (May 2021) no precise information available on this vaccine production process.
Doubling time: ~30 hours (CLS=300192); ~24-30 hours (DSMZ=ACC-305).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Omics: Cell surface proteome.
Omics: CTCF ChIP-seq epigenome analysis.
Omics: H3K4me3 ChIP-seq epigenome analysis.
Omics: Deep antibody staining analysis.
Omics: Deep proteome analysis.
Omics: Genome sequenced.
Omics: DNA methylation analysis.
Omics: Metabolome analysis.
Omics: Methylated arginine analysis by proteomics.
Omics: Myristoylated proteins analysis by proteomics.
Omics: Protein expression by reverse-phase protein arrays.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Omics: Virome analysis using proteomics.
Misspelling: HECK293; Note=Occasionally.
Misspelling: HEK239; Note=Occasionally.
Misspelling: HK293; PubMed=9364930.
Misspelling: HEK-393; Note=Occasionally.
Misspelling: HEK393; Note=Occasionally.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
HLA typingSource: PubMed=25960936
Class I
HLA-AA*02:01,03:01
HLA-BB*07:02,07:02/35:08
HLA-CC*07:02,07:02
Class II
HLA-DQDQA1*01:02,01:02

DQB1*06:02,06:02
HLA-DRDRB1*15:01,15:01

Source: CLS=300192
Class I
HLA-AA*03:01:01
HLA-BB*07:02:01
HLA-CC*07:02:01
Class II
HLA-DPDPB1*04:01:01
HLA-DQDQA1*01:02:01

DQB1*06:02:01
HLA-DRDRB1*15:01:01
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
HierarchyChildren:



CVCL_U658 (211A)CVCL_U659 (211B)CVCL_U660 (211R)
CVCL_6351 (293 EcR Shh)CVCL_2285 (293 GTP-AC-free)CVCL_2286 (293 N3S)
CVCL_4W25 (293 TRE/Cont)CVCL_4W26 (293 TRE/FLAG-POLK)CVCL_9832 (293-CD40)
CVCL_4V25 (293-CD40L)CVCL_8468 (293-Db)CVCL_A8BK (293-Dual Null)
CVCL_XI05 (293-ESM)CVCL_2283 (293-Hektor)CVCL_A8CD (293-hMyD88)
CVCL_9831 (293-IL-1RI)CVCL_8469 (293-Kb)CVCL_A783 (293-LA)
CVCL_VN85 (293-M7)CVCL_2284 (293-PERV-PK-CIRCE)CVCL_A7YI (293-SARS2-S)
CVCL_A7YJ (293-SARS2-S-dfur)CVCL_A5HZ (293-SCARB2)CVCL_M907 (293-VnR)
CVCL_B0NB (293.STAT1 BAX KO)CVCL_RY64 (293_hEcad)CVCL_RY62 (293_hEcad/hSyn2)
CVCL_RY72 (293_hSyn1)CVCL_RY63 (293_hSyn2)CVCL_RY68 (293_hSyn4)
CVCL_DR94 (293/ACE2)CVCL_H362 (293/ADORA1/Galpha15)CVCL_KS32 (293/AP1-luc)
CVCL_JZ01 (293/CFP)CVCL_6352 (293/CHE-Fc)CVCL_H364 (293/CRE-Luc)
CVCL_KS33 (293/CREB-luc)CVCL_J499 (293/CrmA)CVCL_H366 (293/EP1)
CVCL_H368 (293/FP/Galpha15)CVCL_JY88 (293/GFP)CVCL_H369 (293/GHRH/Galpha15)
CVCL_KA76 (293/GNRHR/Galpha15)CVCL_H370 (293/H1)CVCL_Y384 (293/hMD2-CD14)
CVCL_A7YV (293/hNOD1)CVCL_A7YX (293/hNOD2)CVCL_Y385 (293/hTLR1-HA)
CVCL_Y417 (293/hTLR1-TLR2)CVCL_Y386 (293/hTLR10-HA)CVCL_Y387 (293/hTLR2)
CVCL_Y388 (293/hTLR2-CD14)CVCL_Y389 (293/hTLR2-HA)CVCL_Y390 (293/hTLR2-TLR6)
CVCL_Y391 (293/hTLR3)CVCL_Y392 (293/hTLR3-HA)CVCL_Y394 (293/hTLR4-HA)
CVCL_Y393 (293/hTLR4A)CVCL_Y395 (293/hTLR4A-MD2-CD14)CVCL_Y396 (293/hTLR5)
CVCL_Y397 (293/hTLR5-CD14)CVCL_Y398 (293/hTLR5-HA)CVCL_Y399 (293/hTLR6-HA)
CVCL_9V14 (293/KDR)CVCL_Y101 (293/LacZ)CVCL_JY95 (293/Luc)
CVCL_H372 (293/MCH1)CVCL_A7YW (293/mNOD1)CVCL_A7YY (293/mNOD2)
CVCL_Y400 (293/mTLR1)CVCL_Y401 (293/mTLR1-TLR2)CVCL_Y402 (293/mTLR2)
CVCL_Y403 (293/mTLR2-TLR6)CVCL_Y404 (293/mTLR3)CVCL_Y405 (293/mTLR4)
CVCL_Y406 (293/mTLR4-MD2-CD14)CVCL_Y407 (293/mTLR5)CVCL_Y408 (293/mTLR6)
CVCL_Y409 (293/mTLR9)CVCL_KS34 (293/NFkB-luc)CVCL_H373 (293/NPY1)
CVCL_A7YU (293/Null)CVCL_IM63 (293/pmiR-155)CVCL_IM64 (293/pmiR-K12-11)
CVCL_UR29 (293/SF)CVCL_H375 (293/TP)CVCL_JY96 (293/YFP)
CVCL_KA64 (293AAV)CVCL_KA63 (293AD)CVCL_E072 (293GP)
CVCL_C0I5 (293L)CVCL_DD14 (293LAP10)CVCL_DD15 (293LAP13)
CVCL_W338 (293RC21)CVCL_V648 (293sars181A)CVCL_Y381 (293XL/null)
CVCL_6353 (2A)CVCL_6355 (2V6.11)CVCL_B0KY (34893 2L)
CVCL_DD40 (35.32)CVCL_DD41 (37S2.8)CVCL_6361 (90.74)
CVCL_6871 (AAV-293)CVCL_B1AN (Abcam HEK293 ACP1 KO)CVCL_B1AP (Abcam HEK293 ATP13A2 KO)
CVCL_B9VU (Abcam HEK293 CBX4 KO)CVCL_B1AQ (Abcam HEK293 DCP1A KO)CVCL_B1AR (Abcam HEK293 DDX17 KO)
CVCL_B1AS (Abcam HEK293 E2F1 KO)CVCL_B1AT (Abcam HEK293 FGFR3 KO)CVCL_B1AU (Abcam HEK293 FOXC1 KO)
CVCL_B1AV (Abcam HEK293 FOXO3 KO)CVCL_B9VY (Abcam HEK293 FYN KO)CVCL_B9VZ (Abcam HEK293 GAS6 KO)
CVCL_B1AW (Abcam HEK293 GATA2 KO)CVCL_B1AX (Abcam HEK293 GJA1 KO)CVCL_B1AY (Abcam HEK293 GYS1 KO)
CVCL_B1AZ (Abcam HEK293 HK2 KO)CVCL_B1B0 (Abcam HEK293 HOXA9 KO 1)CVCL_B1B1 (Abcam HEK293 HOXA9 KO 2)
CVCL_B1B2 (Abcam HEK293 HRAS KO)CVCL_B1B3 (Abcam HEK293 IFNGR1 KO)CVCL_B1B4 (Abcam HEK293 IRS2 KO)
CVCL_B0YG (Abcam HEK293 JUN KO)CVCL_B1B5 (Abcam HEK293 KMT5A KO)CVCL_B1B6 (Abcam HEK293 LAMP2 KO)
CVCL_B1B7 (Abcam HEK293 MFN2 KO)CVCL_B1B8 (Abcam HEK293 NDRG1 KO)CVCL_B1B9 (Abcam HEK293 NKX2-5 KO)
CVCL_B1BA (Abcam HEK293 PDCD6IP KO)CVCL_B1BB (Abcam HEK293 PHF10 KO)CVCL_B1BC (Abcam HEK293 PHF6 KO)
CVCL_B1BD (Abcam HEK293 PLXNB2 KO)CVCL_B1BE (Abcam HEK293 PRMT6 KO)CVCL_B9W0 (Abcam HEK293 PSENEN KO)
CVCL_B1BF (Abcam HEK293 SDHA KO)CVCL_B0YF (Abcam HEK293 SDHB KO)CVCL_B1BG (Abcam HEK293 SESN2 KO)
CVCL_B1BH (Abcam HEK293 SIRT1 KO)CVCL_B1BI (Abcam HEK293 SMAD5 KO)CVCL_B1BJ (Abcam HEK293 SMARCC1 KO)
CVCL_9804 (AD-293)CVCL_WI47 (AmphoPack-293)CVCL_W339 (AP-1 LUCPorter)
CVCL_C0YH (B'SYS HEK 293 Cav3.2)CVCL_C0YI (B'SYS HEK 293 hERG)CVCL_C0YJ (B'SYS HEK 293 K2P18.1)
CVCL_C0YK (B'SYS HEK 293 KvLQT1/minK)CVCL_C0YL (B'SYS HEK 293 P2X4)CVCL_C0YM (B'SYS HEK 293 P2X7)
CVCL_DD22 (BHH2C)CVCL_DD23 (BHH3)CVCL_DD24 (BHH8)
CVCL_ZZ37 (C8 [Human HEK293 derivative])CVCL_9V15 (CRE8)CVCL_9867 (D1-HEK-293)
CVCL_7261 (EcR-293)CVCL_VK71 (F2N78)CVCL_XB48 (FC33)
CVCL_6902 (FIP293)CVCL_U421 (Flp-In-293)CVCL_U006 (Flp293A)
CVCL_5285 (GFPu-1)CVCL_LB59 (GloResponse 9XGAL4UAS-luc2P HEK293)CVCL_LB60 (GloResponse CRE-luc2P HEK293)
CVCL_LB61 (GloResponse NF-kappaB-RE-luc2P HEK293)CVCL_LB62 (GloResponse NFAT-RE-luc2P HEK293)CVCL_WI48 (GP2-293)
CVCL_JQ47 (h-TREK-1/HEK)CVCL_KU63 (HEK 293 HTR2B Gq)CVCL_AQ26 (HEK 293 STF)
CVCL_V349 (HEK 293 Tet-Off)CVCL_KU39 (HEK 293 Tet-Off Advanced)CVCL_KS31 (HEK 293 Tet-On)
CVCL_V350 (HEK 293 Tet-On 3G)CVCL_KU43 (HEK 293 Tet-On Advanced)CVCL_V351 (HEK 293 tTS)
CVCL_RQ74 (HEK 293/TLR3/NF-kB Luciferase Reporter)CVCL_RQ75 (HEK 293/TLR5/NF-kB Luciferase Reporter)CVCL_RQ76 (HEK 293/TLR7/NF-kB Luciferase Reporter)
CVCL_RQ77 (HEK 293/TLR8/NF-kB Luciferase Reporter)CVCL_RQ78 (HEK 293/TLR9/NF-kB Luciferase Reporter)CVCL_YN15 (HEK-293 hNav1.9)
CVCL_YN16 (HEK-293 mNav1.9)CVCL_YN17 (HEK-293 rNav1.9)CVCL_VT77 (HEK-293-AChE)
CVCL_GR68 (HEK-293-Munc18b)CVCL_9868 (HEK-293-TrkB)CVCL_4W07 (HEK-293.2sus)
CVCL_W457 (HEK-293B1)CVCL_9869 (HEK-293B2)CVCL_9870 (HEK-293CymR)
CVCL_HB82 (HEK-3KO)CVCL_A8CE (HEK-Blue CD40L)CVCL_IM95 (HEK-Blue hMD2-CD14)
CVCL_KT26 (HEK-Blue IFN-alpha/beta)CVCL_UF30 (HEK-Blue IFN-gamma)CVCL_A8CF (HEK-Blue IL-10)
CVCL_UF31 (HEK-Blue IL-12)CVCL_UF32 (HEK-Blue IL-17)CVCL_A8CK (HEK-Blue IL-17C)
CVCL_UF33 (HEK-Blue IL-18)CVCL_UF26 (HEK-Blue IL-2)CVCL_A8CG (HEK-Blue IL-22)
CVCL_A8CH (HEK-Blue IL-23)CVCL_UF59 (HEK-Blue IL-33)CVCL_A8DA (HEK-Blue IL-4/IL-13)
CVCL_UF60 (HEK-Blue IL-6)CVCL_5I78 (HEK-Blue KD-TLR5)CVCL_A7YP (HEK-Blue Null1)
CVCL_A7YN (HEK-Blue Null1-k)CVCL_A7YL (HEK-Blue Null1-v)CVCL_A7YM (HEK-Blue Null2)
CVCL_A7YZ (HEK-Blue Null2-k)CVCL_A8CJ (HEK-Blue RANKL)CVCL_A8BY (HEK-Blue STAT6-hSTING-R232)
CVCL_A8CZ (HEK-Blue TGF-beta)CVCL_UF25 (HEK-Blue TNF-alpha)CVCL_A8CI (HEK-Blue TPO)
CVCL_E339 (HEK-CaSR)CVCL_A7AW (HEK-Dsup)CVCL_A7AY (HEK-DsupdeltaC)
CVCL_A8CQ (HEK-Dual Null)CVCL_A8CY (HEK-Dual IFN-gamma)CVCL_A8CX (HEK-Dual TNF-alpha)
CVCL_A8CN (HEK-Lucia Null)CVCL_A2KB (HEK-OCT3)CVCL_WN84 (HEK-ptdTomato-N1 8)
CVCL_IM79 (HEK-TLR2)CVCL_VI43 (HEK-TLR2-YFP)CVCL_VI44 (HEK-TLR4-YFP)
CVCL_VI46 (HEK-TLR9-YFP)CVCL_2H48 (HEK1.1)CVCL_5I96 (HEK293 (+Galpha16) AequoScreen)
CVCL_C8A7 (HEK293 3xHA ControlTAG)CVCL_0296 (HEK293 482R)CVCL_ZV87 (HEK293 Actin-cpstFRET-Actin)
CVCL_ZV88 (HEK293 Actinin-C-cpstFRET)CVCL_ZV89 (HEK293 Actinin-M-cpstFRET)CVCL_YJ96 (HEK293 ADCYAP1R1 HiTSeeker)
CVCL_YJ97 (HEK293 ADORA2A HiTSeeker)CVCL_YJ98 (HEK293 ADORA2B HiTSeeker)CVCL_YJ99 (HEK293 ADRB2 HiTSeeker)
CVCL_YK00 (HEK293 ADRB3 HiTSeeker)CVCL_5I97 (HEK293 AequoScreen)CVCL_A5CZ (HEK293 APPswe)
CVCL_YK01 (HEK293 AVPR1A HiTSeeker)CVCL_YK02 (HEK293 BDKRB1 HiTSeeker)CVCL_YK03 (HEK293 BDKRB2 HiTSeeker)
CVCL_A3KR (HEK293 C9orf72+/-)CVCL_A3KS (HEK293 C9orf72-/- A)CVCL_A3KT (HEK293 C9orf72-/- B)
CVCL_YK04 (HEK293 CALCR HiTSeeker)CVCL_UR28 (HEK293 Cas9)CVCL_HC62 (HEK293 Cav3.1)
CVCL_HC63 (HEK293 Cav3.2)CVCL_HC64 (HEK293 Cav3.3)CVCL_YK05 (HEK293 CCKBR arrestin-Nomad)
CVCL_YK06 (HEK293 CCKBR calcium-Nomad)CVCL_UF04 (HEK293 CD63 CRISPR)CVCL_B6SF (HEK293 CHI3L1)
CVCL_YK07 (HEK293 CHRM1 HiTSeeker)CVCL_YI91 (HEK293 CNR1 cAMP-Nomad)CVCL_YK08 (HEK293 CNR1 HiTSeeker)
CVCL_YK09 (HEK293 CNR2 HiTSeeker)CVCL_ZV86 (HEK293 cpstFRET-Actin)CVCL_YK10 (HEK293 CRHR2 HiTSeeker)
CVCL_UH22 (HEK293 CYP19A1*1)CVCL_UH23 (HEK293 CYP19A1*3)CVCL_UH24 (HEK293 CYP19A1*4)
CVCL_UG79 (HEK293 CYP1A1*1)CVCL_UG80 (HEK293 CYP1A1*1-V5)CVCL_UG81 (HEK293 CYP1A2*1A)
CVCL_UG82 (HEK293 CYP1A2*1A-V5)CVCL_UG83 (HEK293 CYP1A2*21)CVCL_UG86 (HEK293 CYP2A13*1A)
CVCL_UG87 (HEK293 CYP2A13*1A-V5)CVCL_UG84 (HEK293 CYP2A6*1A)CVCL_UG85 (HEK293 CYP2A6*1A-V5)
CVCL_UG89 (HEK293 CYP2B6*1-V5)CVCL_UH00 (HEK293 CYP2C18*1-V5)CVCL_UH02 (HEK293 CYP2C19*1A-V5)
CVCL_UH03 (HEK293 CYP2C19*1B-V5)CVCL_UH05 (HEK293 CYP2C19-E92D-V5)CVCL_UG90 (HEK293 CYP2C8*1-V5)
CVCL_UG91 (HEK293 CYP2C8*2-V5)CVCL_UG92 (HEK293 CYP2C8*3-V5)CVCL_UG93 (HEK293 CYP2C8*4-V5)
CVCL_UG94 (HEK293 CYP2C9*1)CVCL_UG95 (HEK293 CYP2C9*1-V5)CVCL_UG96 (HEK293 CYP2C9*2-V5)
CVCL_UG97 (HEK293 CYP2C9*3-V5)CVCL_UG98 (HEK293 CYP2C9*8-V5)CVCL_UG99 (HEK293 CYP2C9*9-V5)
CVCL_UH09 (HEK293 CYP2D6*10)CVCL_UH10 (HEK293 CYP2D6*17-V5)CVCL_UH07 (HEK293 CYP2D6*1A-V5)
CVCL_UH08 (HEK293 CYP2D6*2-V5)CVCL_UH11 (HEK293 CYP2E1*1A)CVCL_UH12 (HEK293 CYP2E1*1A-V5)
CVCL_UH13 (HEK293 CYP2J2*1-V5)CVCL_UH16 (HEK293 CYP3A4*15-V5)CVCL_UH15 (HEK293 CYP3A4*1A-V5)
CVCL_UH17 (HEK293 CYP3A5*1)CVCL_UH18 (HEK293 CYP3A5*1-V5)CVCL_UH20 (HEK293 CYP3A7*2-V5)
CVCL_UH21 (HEK293 CYP4A11*1-V5)CVCL_YK11 (HEK293 DRD1 cAMP-Nomad)CVCL_YK12 (HEK293 DRD1 HiTSeeker)
CVCL_YK13 (HEK293 DRD5 HiTSeeker)CVCL_YK14 (HEK293 FSHR Fluo-HiTSeeker)CVCL_YK15 (HEK293 FSHR HiTSeeker)
CVCL_A0TJ (HEK293 FUS KO)CVCL_B6SE (HEK293 GFP-DUSP12)CVCL_C3NG (HEK293 GOT2 KO clone A3)
CVCL_C3NH (HEK293 GOT2 KO clone A6)CVCL_C3NI (HEK293 GOT2 KO clone A7)CVCL_A5IP (HEK293 HADH-/-)
CVCL_C0UG (HEK293 HLA-A*01:01)CVCL_C0UH (HEK293 HLA-A*02:01)CVCL_C0UI (HEK293 HLA-A*03:01)
CVCL_C0UJ (HEK293 HLA-A*11:01)CVCL_C0UK (HEK293 HLA-A*24:02)CVCL_C0UL (HEK293 HLA-A*26:02)
CVCL_C0UM (HEK293 HLA-A*31:01)CVCL_C0UN (HEK293 HLA-A*33:03)CVCL_XZ52 (HEK293 human APP695)
CVCL_XZ53 (HEK293 human APP695 Swedish)CVCL_YK16 (HEK293 LHCGR Fluo-HiTSeeker)CVCL_YK17 (HEK293 LHCGR HiTSeeker)
CVCL_YK18 (HEK293 MC4R HiTSeeker)CVCL_C0TZ (HEK293 MUT-KO clone 2)CVCL_C0D2 (HEK293 NDUSF2 KO)
CVCL_ZW92 (HEK293 Nav1.7)CVCL_KS50 (HEK293 p65-HaloTag)CVCL_YK19 (HEK293 PTGER2 HiTSeeker)
CVCL_YK20 (HEK293 PTGER4 HiTSeeker)CVCL_RY69 (HEK293 rLN10)CVCL_YD69 (HEK293 RPS2 A226Y)
CVCL_YD70 (HEK293 RPS2 WT)CVCL_RY71 (HEK293 rLN8)CVCL_WS18 (HEK293 SCN1A/SCN1B/SCN2B)
CVCL_S025 (HEK293 SimpleCell O-GalNAc)CVCL_YK21 (HEK293 TACR1 HiTSeeker)CVCL_YK22 (HEK293 tGFP-BACE1)
CVCL_B5E1 (HEK293 THAP11F80L #8)CVCL_B5E2 (HEK293 THAP11HBM #1)CVCL_B5DT (HEK293 THAP7DCC #27)
CVCL_B5DU (HEK293 THAP7DCC #36)CVCL_B5DV (HEK293 THAP7DCC #40)CVCL_B5DS (HEK293 THAP7DCC #7)
CVCL_B5DW (HEK293 THAP7HBM #34)CVCL_B5DX (HEK293 THAP7HBM #76)CVCL_B5DY (HEK293 THAP7null #29)
CVCL_B5DZ (HEK293 THAP7null #32)CVCL_B5E0 (HEK293 THAP7null #44)CVCL_C8A6 (HEK293 TMEM115-3xHA GolgiTAG)
CVCL_YK23 (HEK293 TSHR HiTSeeker)CVCL_YK24 (HEK293 VIPR1 HiTSeeker)CVCL_JZ97 (HEK293_GS-KO)
CVCL_6910 (HEK293-A)CVCL_E149 (HEK293-A7)CVCL_C0RY (HEK293-ACE2-GFP)
CVCL_ZD63 (HEK293-CAGA)CVCL_YJ21 (HEK293-CB1)CVCL_C0EF (HEK293-CEACAM1-dN-Fc)
CVCL_C0EG (HEK293-CEACAM1-Fc)CVCL_C0EH (HEK293-CEACAM1-N-Fc)CVCL_C0EI (HEK293-CEACAM3-Fc)
CVCL_C0EJ (HEK293-CEACAM5-Fc)CVCL_C0EK (HEK293-CEACAM6-Fc)CVCL_C0EL (HEK293-CEACAM8-Fc)
CVCL_C0RU (HEK293-CNG)CVCL_C0RW (HEK293-CNG-Gs)CVCL_6974 (HEK293-EBNA)
CVCL_EP72 (HEK293-EPHB1)CVCL_EP73 (HEK293-EPHB2)CVCL_6996 (HEK293-ET)
CVCL_6642 (HEK293-F)CVCL_6643 (HEK293-H)CVCL_ZC53 (HEK293-hCNR1)
CVCL_ZC54 (HEK293-hCNR2)CVCL_C0RT (HEK293-hERG)CVCL_ZC15 (HEK293-hGPR55)
CVCL_VP06 (HEK293-HM3)CVCL_WI13 (HEK293-hNOTCH1)CVCL_WI14 (HEK293-hNOTCH2)
CVCL_VP07 (HEK293-HR1)CVCL_C0N2 (HEK293-IRF3)CVCL_C0NM (HEK293-KL)
CVCL_B7NW (HEK293-Luc-GFP)CVCL_B7NX (HEK293-Luc-RFP)CVCL_C0EM (HEK293-MacCEACAM1-Fc)
CVCL_ZC55 (HEK293-mCnr1)CVCL_ZC56 (HEK293-mCnr2)CVCL_ZC16 (HEK293-mGpr55)
CVCL_B3N0 (HEK293-mir122)CVCL_B3Q1 (HEK293-MRP7)CVCL_B7SA (HEK293-MRP7-C17)
CVCL_B7SB (HEK293-MRP7-C18)CVCL_A0GH (HEK293-mST2L)CVCL_B7NY (HEK293-NanoLuc-RFP)
CVCL_5I43 (HEK293-Nav 1.3)CVCL_WG86 (HEK293-Nrf2 clone 1)CVCL_WG87 (HEK293-Nrf2 clone 2)
CVCL_C0EN (HEK293-ratCEACAM1-dN-Fc)CVCL_C0EP (HEK293-ratCEACAM1-Fc)CVCL_ZC57 (HEK293-rCnr1)
CVCL_ZC58 (HEK293-rCnr2)CVCL_C5TT (HEK293-SLC1A5)CVCL_VR42 (HEK293-SREBP1-T2A-luciferase-KI)
CVCL_A8UL (HEK293-Survivin)CVCL_RZ86 (HEK293-YFV-prM/E-opt)CVCL_H513 (HEK293/5-HT2C)
CVCL_H514 (HEK293/AT1)CVCL_KA11 (HEK293/Galpha15)CVCL_H515 (HEK293/GCGR/Galpha15)
CVCL_5A22 (HEK293/GFP-DFCP1)CVCL_H516 (HEK293/hERG)CVCL_H517 (HEK293/hKv1.5)
CVCL_H518 (HEK293/hKv4.2)CVCL_H519 (HEK293/hNav1.5)CVCL_H520 (HEK293/hNav1.7)
CVCL_KA65 (HEK293/NFAT/beta-lactamase)CVCL_KA07 (HEK293/PD-L1)CVCL_KA75 (HEK293/PTHR1/CRE/beta-lactamase)
CVCL_M775 (HEK293L)CVCL_A784 (HEK293S)CVCL_0063 (HEK293T)
CVCL_UL49 (HEK293TN)CVCL_HB83 (HEKR1)CVCL_HB84 (HEKR2)
CVCL_HB85 (HEKR2R1)CVCL_HB86 (HEKR2R3)CVCL_HB87 (HEKR3)
CVCL_HB88 (HEKR3R1)CVCL_2491 (HH-8)CVCL_E065 (HKb20)
CVCL_A5BV (Hki-8)CVCL_A5BU (HKiG2)CVCL_N700 (HL-2)
CVCL_WK50 (iLite VEGF Assay Ready Cells)CVCL_KW01 (InCELL Hunter HEK 293 BAZ2A Bromodomain)CVCL_KW02 (InCELL Hunter HEK 293 BRD2(1) Bromodomain)
CVCL_KW03 (InCELL Hunter HEK 293 BRD2(1,2) Bromodomain)CVCL_KW04 (InCELL Hunter HEK 293 BRD3(1) Bromodomain)CVCL_KW05 (InCELL Hunter HEK 293 BRD3(1,2) Bromodomain)
CVCL_KW06 (InCELL Hunter HEK 293 BRD4(1) Bromodomain)CVCL_KW07 (InCELL Hunter HEK 293 BRDT(1) Bromodomain)CVCL_KW08 (InCELL Hunter HEK 293 BRDT(1,2) Bromodomain)
CVCL_KW09 (InCELL Hunter HEK 293 SMARCA4 Bromodomain)CVCL_KW10 (InCELL Hunter HEK 293 TAF1L(2) Bromodomain)CVCL_5I63 (K177)
CVCL_YJ80 (LINTERNA HEK293)CVCL_A8GJ (MAIL8-19)CVCL_0406 (MAIL8-3)
CVCL_A9P3 (NF-KappaB reporter (Luc)-HEK293)CVCL_ZL50 (NOX1-HEK293)CVCL_ZL51 (NOX4-HEK293)
CVCL_KZ31 (PathHunter HEK 293 ADRA1D(82-572) beta-arrestin)CVCL_KZ32 (PathHunter HEK 293 ADRB2 Total GPCR Internalization)CVCL_KZ33 (PathHunter HEK 293 AVPR2 beta-arrestin)
CVCL_KZ34 (PathHunter HEK 293 BDKRB2 beta-arrestin)CVCL_KZ35 (PathHunter HEK 293 beta-arrestin1-EA Parental)CVCL_KZ36 (PathHunter HEK 293 beta-arrestin2-EA Parental)
CVCL_KZ37 (PathHunter HEK 293 CCKAR beta-arrestin)CVCL_KZ38 (PathHunter HEK 293 CCR2 beta-arrestin)CVCL_KZ39 (PathHunter HEK 293 CCR7 beta-arrestin)
CVCL_KZ40 (PathHunter HEK 293 CNR2 beta-arrestin)CVCL_KZ41 (PathHunter HEK 293 CXCR2 beta-arrestin)CVCL_KZ42 (PathHunter HEK 293 CXCR6 beta-arrestin)
CVCL_KZ43 (PathHunter HEK 293 cyno CXCR1 beta-arrestin)CVCL_KZ44 (PathHunter HEK 293 cyno CXCR2 beta-arrestin)CVCL_KZ45 (PathHunter HEK 293 EDG1 Total GPCR Internalization)
CVCL_KZ46 (PathHunter HEK 293 EDG3 beta-arrestin)CVCL_KZ47 (PathHunter HEK 293 F2RL1 beta-arrestin)CVCL_KZ48 (PathHunter HEK 293 FFAR1 beta-arrestin-1)
CVCL_KZ49 (PathHunter HEK 293 GCGR Total GPCR Internalization)CVCL_KZ50 (PathHunter HEK 293 GPR119 beta-arrestin)CVCL_KZ51 (PathHunter HEK 293 GPR120L Total GPCR Internalization)
CVCL_KZ52 (PathHunter HEK 293 GPR150 beta-arrestin)CVCL_KZ53 (PathHunter HEK 293 GPR152 beta-arrestin)CVCL_KZ54 (PathHunter HEK 293 GPR173 beta-arrestin)
CVCL_KZ55 (PathHunter HEK 293 GPR20 beta-arrestin)CVCL_KZ56 (PathHunter HEK 293 GPR45 beta-arrestin)CVCL_KZ57 (PathHunter HEK 293 GRPR beta-arrestin)
CVCL_KZ58 (PathHunter HEK 293 IkappaB Degradation)CVCL_KZ59 (PathHunter HEK 293 LXRbeta-NCoR1 Protein Interaction)CVCL_KZ60 (PathHunter HEK 293 mGPR120 beta-arrestin)
CVCL_KZ61 (PathHunter HEK 293 P2RY4 beta-arrestin)CVCL_KZ62 (PathHunter HEK 293 PTGER2 beta-arrestin)CVCL_KZ63 (PathHunter HEK 293 PTGER4 beta-arrestin)
CVCL_KZ64 (PathHunter HEK 293 PTGIR beta-arrestin)CVCL_KZ65 (PathHunter HEK 293 RELA-IkappaB Nuclear Translocation)CVCL_KZ66 (PathHunter HEK 293 SCTR beta-arrestin)
CVCL_KZ67 (PathHunter HEK 293 SSTR3 beta-arrestin)CVCL_3772 (pEAK Rapid)CVCL_JY47 (PLT460F_(DDR2))
CVCL_RQ69 (PrecisION hCav1.2 alpha1C/beta2a/alpha2-delta1-HEK)CVCL_LC62 (PrecisION hERG-HEK)CVCL_RQ84 (PrecisION hHCN1-HEK)
CVCL_RQ85 (PrecisION hHCN2-HEK)CVCL_RQ83 (PrecisION hHCN3-HEK)CVCL_RQ81 (PrecisION hNav1.1-HEK)
CVCL_LC67 (PrecisION hNav1.5-HEK)CVCL_LC68 (PrecisION hNav1.6-HEK)CVCL_RQ80 (PrecisION hNav1.7-HEK)
CVCL_8967 (ProPak-A.52)CVCL_8968 (ProPak-A.6)CVCL_8969 (ProPak-X.36)
CVCL_VQ64 (SCL215)CVCL_VQ89 (SCL60)CVCL_6448 (SODk1)
CVCL_D585 (T-REx-293)CVCL_8117 (Tet-iNOS-293)CVCL_2737 (tsA201)
CVCL_5I80 (ValiScreen human TRPC3)CVCL_5I81 (ValiScreen human TRPC6)CVCL_YJ67 (VAMPIRO HEK293)
CVCL_2767 (WSS-1)

Sex of cellFemale
Age at samplingFetus
CategoryTransformed cell line
STR profileSource(s): ATCC; CCRID; CLS; DSMZ; ECACC; JCRB; KCLB; PubMed=11416159; PubMed=15218237; RCB; TKG

Markers:
AmelogeninX
CSF1PO11,12
D2S133819
D3S135815,17
D5S8188,9
D7S82011,12
D8S117912,14
D13S31712 (JCRB; TKG)
12,14 (ATCC; CCRID; CLS; DSMZ; ECACC; KCLB; PubMed=15218237; RCB)
D16S5399 (DSMZ)
9,13 (ATCC; CCRID; CLS; ECACC; JCRB; RCB; TKG)
D18S5117 (PubMed=15218237)
17,18 (CCRID; PubMed=11416159)
18 (CLS; DSMZ)
D19S43315,18 (CCRID)
18 (CLS; DSMZ)
D21S1128,30.2
FGA23
Penta D9,10
Penta E7,15
TH017,9.3
TPOX11
vWA16,19

Run an STR similarity search on this cell line
Web pageshttps://en.wikipedia.org/wiki/HEK_293_cells
http://www.hek293.com/
http://hek293genome.org/v2/
http://www.cells-talk.com/index.php/page/copelibrary?key=HEK293
https://www.phe-culturecollections.org.uk/news/ecacc-news/sticky-issues-with-293-cells.aspx
https://www.proteinatlas.org/learn/cellines
http://141.61.102.20/mxdb/project/show/9191407937500
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/2/cell-lines-detail-176.html
https://web.archive.org/web/20140910211526/http://webserver.mbi.ufl.edu/~shaw/293.html
https://cell-map.org/
https://tcpaportal.org/mclp/
https://www.precisionvaccinations.com/vaccines/sputnik-v-vaccine
Publications

PubMed=886304; DOI=10.1099/0022-1317-36-1-59
Graham F.L., Smiley J., Russell W.C., Nairn R.
Characteristics of a human cell line transformed by DNA from human adenovirus type 5.
J. Gen. Virol. 36:59-74(1977)

PubMed=9217065; DOI=10.1006/viro.1997.8597
Louis N., Evelegh C., Graham F.L.
Cloning and sequencing of the cellular-viral junctions from the human adenovirus type 5 transformed 293 cell line.
Virology 233:423-429(1997)

PubMed=15218237; DOI=10.1159/000078556
Bylund L., Kytola S., Lui W.-O., Larsson C., Weber G.
Analysis of the cytogenetic stability of the human embryonal kidney cell line 293 by cytogenetic and STR profiling approaches.
Cytogenet. Genome Res. 106:28-32(2004)

PubMed=21502043
Rubino M.J.
Experiences with HEK293: a human cell line.
PDA J. Pharm. Sci. Technol. 64:392-395(2010)

PubMed=21214938; DOI=10.1186/1471-2164-12-14
Atwood B.K., Lopez J., Wager-Miller J., Mackie K., Straiker A.
Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis.
BMC Genomics 12:14.1-14.14(2011)

PubMed=21269460; DOI=10.1186/1752-0509-5-17
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol. 5:17.1-17.13(2011)

PubMed=22278370; DOI=10.1074/mcp.M111.014050
Geiger T., Wehner A., Schaab C., Cox J., Mann M.
Comparative proteomic analysis of eleven common cell lines reveals ubiquitous but varying expression of most proteins.
Mol. Cell. Proteomics 11:M111.014050-M111.014050(2012)

PubMed=23325432; DOI=10.1101/gr.147942.112
Varley K.E., Gertz J., Bowling K.M., Parker S.L., Reddy T.E., Pauli-Behn F., Cross M.K., Williams B.A., Stamatoyannopoulos J.A., Crawford G.E., Absher D.M., Wold B.J., Myers R.M.
Dynamic DNA methylation across diverse human cell lines and tissues.
Genome Res. 23:555-567(2013)

PubMed=24618588; DOI=10.1371/journal.pone.0091433
Chernobrovkin A.L., Zubarev R.A.
Detection of viral proteins in human cells lines by xeno-proteomics: elimination of the last valid excuse for not testing every cellular proteome dataset for viral proteins.
PLoS ONE 9:E91433-E91433(2014)

PubMed=25182477; DOI=10.1038/ncomms5767
Lin Y.-C., Boone M., Meuris L., Lemmens I., Van Roy N., Soete A., Reumers J., Moisse M., Plaisance S., Drmanac R., Chen J., Speleman F., Lambrechts D., Van de Peer Y., Tavernier J., Callewaert N.
Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations.
Nat. Commun. 5:4767.1-4767.12(2014)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

PubMed=25807930; DOI=10.1002/anie.201500342
Broncel M., Serwa R.A., Ciepla P., Krause E., Dallman M.J., Magee A.I., Tate E.W.
Multifunctional reagents for quantitative proteome-wide analysis of protein modification in human cells and dynamic profiling of protein lipidation during vertebrate development.
Angew. Chem. Int. Ed. 54:5948-5951(2015)

PubMed=25894527; DOI=10.1371/journal.pone.0121314
Bausch-Fluck D., Hofmann A., Bock T., Frei A.P., Cerciello F., Jacobs A., Moest H., Omasits U., Gundry R.L., Yoon C., Schiess R., Schmidt A., Mirkowska P., Hartlova A.S., Van Eyk J.E., Bourquin J.-P., Aebersold R., Boheler K.R., Zandstra P.W., Wollscheid B.
A mass spectrometric-derived cell surface protein atlas.
PLoS ONE 10:E0121314-E0121314(2015)

PubMed=25903999; DOI=10.1002/biot.201400388
Genzel Y.
Designing cell lines for viral vaccine production: where do we stand?
Biotechnol. J. 10:728-740(2015)

PubMed=27233776; DOI=10.1002/pmic.201500349
Lobas A.A., Karpov D.S., Kopylov A.T., Solovyeva E.M., Ivanov M.V., Ilina I.Y., Lazarev V.N., Kuznetsova K.G., Ilgisonis E.V., Zgoda V.G., Gorshkov M.V., Moshkovskii S.A.
Exome-based proteogenomics of HEK-293 human cell line: coding genomic variants identified at the level of shotgun proteome.
Proteomics 16:1980-1991(2016)

PubMed=27577262; DOI=10.1126/scisignal.aaf7329
Larsen S.C., Sylvestersen K.B., Mund A., Lyon D., Mullari M., Madsen M.V., Daniel J.A., Jensen L.J., Nielsen M.L.
Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells.
Sci. Signal. 9:Rs9.1-Rs9.15(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

DOI=10.13005/bpj/1414
Yuan J., Xu W.W.-W., Jiang S.Y.-L., Yu H.X.-Y., Poon H.-F.
The scattered twelve tribes of HEK293.
Biomed. Pharmacol. J. 11:621-623(2018)

PubMed=29660373; DOI=10.1016/j.bbagen.2018.04.012
Touat-Hamici Z., Bulteau A.-L., Bianga J., Jean-Jacques H., Szpunar J., Lobinski R., Chavatte L.
Selenium-regulated hierarchy of human selenoproteome in cancerous and immortalized cells lines.
Biochim. Biophys. Acta 1862:2493-2505(2018)

PubMed=30260228; DOI=10.1021/acs.jproteome.8b00538
Knott M.E., Manzi M., Zabalegui N., Salazar M.O., Puricelli L.I., Monge M.E.
Metabolic footprinting of a clear cell renal cell carcinoma in vitro model for human kidney cancer detection.
J. Proteome Res. 17:3877-3888(2018)

PubMed=32302230; DOI=10.1089/hum.2020.29116.oxg
OXGENE
Live and let live: the remarkable story of HEK293 cells.
Hum. Gene Ther. 31:485-487(2020)

Cross-references
Cell line databases/resourcesCLO; CLO_0001230
CLO; CLO_0050903
MCCL; MCC:0000006
CLDB; cl45
CLDB; cl46
CLDB; cl47
CLDB; cl7133
CCRID; 1101HUM-PUMC000010
CCRID; 1102HUM-NIFDC00005
CCRID; 3101HUMGNHu18
CCRID; 3101HUMGNHu43
CCRID; 4201HUM-CCTCC00067
CCRID; 5301HUM-KCB09071YJ
DSMZCellDive; ACC-305
FCS-free; 6-2-7-1-4-3
FCS-free; 6-2-42-1-8-11
FCS-free; 6-2-45-1-8-3
FCS-free; 6-2-46-1-8-11
FCS-free; 6-2-284-1-4-3
FCS-free; 6-2-345-1-4-12
FCS-free; 6-2-372-1-16-3
FCS-free; 6-2-381-1-4-3
FCS-free; 6-2-409-1-16-12
FCS-free; 6-2-421-2-4-7
FCS-free; 6-2-503-1-3-3
FCS-free; 6-2-533-1-4-12
FCS-free; 6-2-570-3-17-1
FCS-free; 6-2-586-1-18-2
Lonza; 46
TOKU-E; 31
Anatomy/cell type resourcesBTO; BTO:0000007
Biological sample resources4DN; 4DNSRVF4XB1F
BioSample; SAMN03471398
BioSample; SAMN03473347
BioSamples; SAMEA2018185
ENCODE; ENCBS022BLS
ENCODE; ENCBS037XHS
ENCODE; ENCBS209KHO
ENCODE; ENCBS253HIE
ENCODE; ENCBS264HQL
ENCODE; ENCBS375ENC
ENCODE; ENCBS393ENC
ENCODE; ENCBS421ENC
ENCODE; ENCBS439ENC
ENCODE; ENCBS479AAA
ENCODE; ENCBS480AAA
ENCODE; ENCBS481AAA
ENCODE; ENCBS482AAA
ENCODE; ENCBS483AAA
ENCODE; ENCBS484AAA
ENCODE; ENCBS486AAA
ENCODE; ENCBS522ENC
ENCODE; ENCBS523ENC
ENCODE; ENCBS613RZL
ENCODE; ENCBS906GPZ
Cell line collections (Providers)Abcam; ab259776
Abcam; ab277915
AddexBio; T0011001/76
ATCC; CRL-1573
ATCC; PTA-4488
BCRC; 60019
BCRJ; 0009
BEI_Resources; NR-9313
CCLV; CCLV-RIE 0197
CCTCC; GDC0067
CLS; 300192
DSMZ; ACC-305
ECACC; 85120602
HIVReagentProgram; ARP-103
IBRC; C10139
ICLC; HTL03003
IZSLER; BS CL 129
JCRB; JCRB9068
KCB; KCB 200408YJ
KCB; KCB 200971YJ
KCLB; 21573
NCBI_Iran; C497
RCB; RCB1637
TKG; TKG 0306
Chemistry resourcesChEMBL-Cells; CHEMBL3307715
ChEMBL-Targets; CHEMBL614818
PubChem_Cell_line; CVCL_0045
Encyclopedic resourcesWikidata; Q489618
Experimental variables resourcesEFO; EFO_0001182
Gene expression databasesGEO; GSM580027
GEO; GSM580028
GEO; GSM635701
GEO; GSM635702
GEO; GSM635703
GEO; GSM635704
GEO; GSM651571
GEO; GSM749668
GEO; GSM749687
GEO; GSM749767
GEO; GSM945256
GEO; GSM945288
GEO; GSM1374525
Medical resourcesMeSH; D057809
Metabolomic databasesMetaboLights; MTBLS102
MetaboLights; MTBLS156
MetaboLights; MTBLS737
Proteomic databasesPRIDE; PXD000589
PRIDE; PXD000623
PRIDE; PXD000680
PRIDE; PXD000933
PRIDE; PXD000953
PRIDE; PXD001468
PRIDE; PXD001511
PRIDE; PXD001711
PRIDE; PXD001863
PRIDE; PXD002383
PRIDE; PXD002389
PRIDE; PXD002395
PRIDE; PXD002601
PRIDE; PXD002613
PRIDE; PXD002676
PRIDE; PXD003310
PRIDE; PXD003370
PRIDE; PXD003700
PRIDE; PXD003896
PRIDE; PXD005535
PRIDE; PXD005955
PRIDE; PXD009668
PRIDE; PXD014771
PRIDE; PXD017977
PRIDE; PXD030601
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number42

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