Cell line name | C2C12 | |||||||||||||||||||||
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Synonyms | C2c12; C2-C12; C12 | |||||||||||||||||||||
Accession | BTCC-2006 | |||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: C2C12 (BTCC-2006) | |||||||||||||||||||||
Comments | Part of: ENCODE project mouse cell lines. Characteristics: Capable, upon starvation, of differentiating into contractile myotubes that express muscle-specific proteins. Doubling time: 19.6 +- 0.4 hours (Note=At 22th passage), 18.4 +- 0.2 (Note=At 38th passage) (PubMed=22020321); ~20 hours (DSMZ=ACC-565). Omics: Cell surface proteome. Omics: Deep proteome analysis. Omics: H3K27me3 ChIP-seq epigenome analysis. Omics: H3K36me3 ChIP-seq epigenome analysis. Omics: H3K4me3 ChIP-seq epigenome analysis. Omics: H3K79me2 ChIP-seq epigenome analysis. Omics: H3K79me3 ChIP-seq epigenome analysis. Omics: Metabolome analysis. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Misspelling: C1C12; Note=Occasionally. Derived from site: In situ; Skeletal muscle; UBERON=UBERON_0001134. Cell type: Myoblast; CL=CL_0000056. | |||||||||||||||||||||
Species of origin | Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C3H. | |||||||||||||||||||||
Hierarchy | Parent: CVCL_6812 (C2 [Mouse myoblast]) Children:
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Sex of cell | Female | |||||||||||||||||||||
Age at sampling | 2M | |||||||||||||||||||||
Category | Spontaneously immortalized cell line | |||||||||||||||||||||
Web pages | https://en.wikipedia.org/wiki/C2C12 https://www.phe-culturecollections.org.uk/media/157858/c2c12-cell-line-profile.pdf https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-123.html https://web.archive.org/web/20130502024425/http://www.stanford.edu/group/blau/protocols/c2lineprotocol.html | |||||||||||||||||||||
Publications | PubMed=563524; DOI=10.1038/270725a0 PubMed=8023908; DOI=10.1152/ajpcell.1994.266.6.C1795 PubMed=15596414 PubMed=19298647; DOI=10.1186/1471-2121-10-20 PubMed=19350625; DOI=10.1002/bit.22318 PubMed=20635352; DOI=10.1002/bit.22865 PubMed=22020321; DOI=10.1016/j.yexcr.2011.10.004 PubMed=24735950; DOI=10.1016/j.scr.2014.03.004 PubMed=25277546; DOI=10.1186/1471-2164-15-847 PubMed=25894527; DOI=10.1371/journal.pone.0121314 | |||||||||||||||||||||
Cross-references | ||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0002071 CLO; CLO_0050871 MCCL; MCC:0000079 CLDB; cl563 CLDB; cl564 CLDB; cl5172 CCRID; 1101MOU-PUMC000099 CCRID; 3101MOUGNM26 CCRID; 3101MOUSCSP505 CCRID; 4201MOU-CCTCC00175 DSMZCellDive; ACC-565 FCS-free; 221-5-486-3-3 FCS-free; 221-5-527-1-3-3 FCS-free; 221-17-457-3-4-3 FCS-free; 221-17-505-3-4-12 FCS-free; 221-21-488-3-4-12 Lonza; 692 TOKU-E; 728 | |||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0000165 | |||||||||||||||||||||
Biological sample resources | ENCODE; ENCBS124ENC ENCODE; ENCBS299ZOZ ENCODE; ENCBS981MXJ | |||||||||||||||||||||
Cell line collections (Providers) | Abcam; ab279976 AddexBio; P0028001/4665 ATCC; CRL-1772 BCRC; 60083 BCRJ; 0058 CCTCC; GDC0175 CLS; 400476 DSMZ; ACC-565 ECACC; 91031101 IZSLER; BS CL 148 KCB; KCB 2012115YJ NCBI_Iran; C521 RCB; RCB0987 | |||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308003 ChEMBL-Targets; CHEMBL612655 PubChem_Cell_line; CVCL_0188 | |||||||||||||||||||||
Encyclopedic resources | Wikidata; Q5008075 | |||||||||||||||||||||
Experimental variables resources | EFO; EFO_0001098 |