MIN6小鼠胰岛β细胞

价 格:¥2400

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-2008

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameMIN6
SynonymsMin6; MIN-6; Mouse INsulinoma 6
AccessionBBTCC-2008
Resource Identification InitiativeTo cite this cell line use: MIN6 (BTCC-2008)
CommentsTransformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Cell surface proteome.
Omics: Endoplasmic reticulum proteome analysis.
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Pancreatic beta cell; CL=CL_0000169.
DiseaseMouse insulinoma (NCIt: C34053)
Species of originMus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 IT6 transgenic.
HierarchyChildren:



CVCL_A7QH (MIN6 rho0)CVCL_A8QH (MIN6-cl4)CVCL_4372 (MIN6-m14)
CVCL_4371 (MIN6-m9)CVCL_D686 (MIN6N8)
Sex of cellSex unspecified
Age at sampling13W
CategoryTransformed cell line
Web pageshttps://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/m/cell-lines-detail-93.html
Publications

PubMed=2163307; DOI=10.1210/endo-127-1-126
Miyazaki J.-I., Araki K., Yamato E., Ikegami H., Asano T., Shibasaki Y., Oka Y., Yamamura K.-I.
Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms.
Endocrinology 127:126-132(1990)

PubMed=8697299
Poitout V., Olson L.K., Robertson R.P.
Insulin-secreting cell lines: classification, characteristics and potential applications.
Diabetes Metab. 22:7-14(1996)

PubMed=8824267; DOI=10.1074/jbc.271.42.26194
Soejima A., Inoue K., Takai D., Kaneko M., Ishihara H., Oka Y., Hayashi J.-I.
Mitochondrial DNA is required for regulation of glucose-stimulated insulin secretion in a mouse pancreatic beta cell line, MIN6.
J. Biol. Chem. 271:26194-26199(1996)

PubMed=18845907; DOI=10.1507/endocrj.K08E-172
Nakashima K., Kanda Y., Hirokawa Y., Kawasaki F., Matsuki M., Kaku K.
MIN6 is not a pure beta cell line but a mixed cell line with other pancreatic endocrine hormones.
Endocr. J. 56:45-53(2009)

PubMed=22538498; DOI=10.1159/000338793
Grozinsky-Glasberg S., Shimon I., Rubinfeld H.
The role of cell lines in the study of neuroendocrine tumors.
Neuroendocrinology 96:173-187(2012)

PubMed=22808281; DOI=10.1371/journal.pone.0040868
Cheng K., Delghingaro-Augusto V., Nolan C.J., Turner N., Hallahan N., Andrikopoulos S., Gunton J.E.
High passage MIN6 cells have impaired insulin secretion with impaired glucose and lipid oxidation.
PLoS ONE 7:E40868-E40868(2012)

PubMed=23560115; DOI=10.1371/journal.pone.0061211
Yamato E., Tashiro F., Miyazaki J.-I.
Microarray analysis of novel candidate genes responsible for glucose-stimulated insulin secretion in mouse pancreatic beta cell line MIN6.
PLoS ONE 8:E61211-E61211(2013)

PubMed=25546123; DOI=10.1002/pmic.201400345
Lee J.-S., Wu Y.-N., Schnepp P., Fang J.-Y., Zhang X.-B., Karnovsky A., Woods J., Stemmer P.M., Liu M., Zhang K.-Z., Chen X.-Q.
Proteomics analysis of rough endoplasmic reticulum in pancreatic beta cells.
Proteomics 15:1508-1511(2015)

PubMed=25894527; DOI=10.1371/journal.pone.0121314
Bausch-Fluck D., Hofmann A., Bock T., Frei A.P., Cerciello F., Jacobs A., Moest H., Omasits U., Gundry R.L., Yoon C., Schiess R., Schmidt A., Mirkowska P., Hartlova A.S., Van Eyk J.E., Bourquin J.-P., Aebersold R., Boheler K.R., Zandstra P.W., Wollscheid B.
A mass spectrometric-derived cell surface protein atlas.
PLoS ONE 10:E0121314-E0121314(2015)

Cross-references
Cell line databases/resourcesMCCL; MCC:0000326
Lonza; 163
Anatomy/cell type resourcesBTO; BTO:0002284
Cell line collections (Providers)AddexBio; C0018008/403
BCRJ; 0293
IBRC; C10524
Chemistry resourcesChEMBL-Cells; CHEMBL4483177
ChEMBL-Targets; CHEMBL4483258
PubChem_Cell_line; CVCL_0431
Encyclopedic resourcesWikidata; Q12513178
Experimental variables resourcesEFO; EFO_0002829
Proteomic databasesPRIDE; PXD000589
PRIDE; PXD001081

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