BV2小鼠小胶质细胞

价 格:¥1800

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-2015

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameBV-2
SynonymsBV2
AccessionBTCC-2015
Resource Identification InitiativeTo cite this cell line use: BV-2 (BTCC-2015)
CommentsTransformant: Recombinant retrovirus J2.
Omics: Secretome proteome analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Cell type: Microglial cell; CL=CL_0000129.
Species of originMus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
HierarchyChildren:



CVCL_ZJ35 (BV-2 PU.1 KO)CVCL_XD67 (BV2-EGFP)CVCL_WJ28 (BV2-mCherry)
CVCL_XD66 (BV2-tDT)

Sex of cellFemale
Age at sampling1W
CategoryTransformed cell line
Publications

PubMed=2110186; DOI=10.1016/0165-5728(90)90073-V
Blasi E., Barluzzi R., Bocchini V., Mazzolla R., Bistoni F.
Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus.
J. Neuroimmunol. 27:229-237(1990)

PubMed=19565166; DOI=10.14573/altex.2009.2.83
Henn A., Lund S., Hedtjarn M., Schrattenholz A., Porzgen P., Leist M.
The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation.
ALTEX 26:83-94(2009)

PubMed=21961028; DOI=10.2174/1877381801002010148
Crain J.M., Watters J.J.
Estrogen and P2 purinergic receptor systems in microglia: therapeutic targets for neuroprotection.
Open Drug Discov. J. 2:148-167(2010)

PubMed=21214938; DOI=10.1186/1471-2164-12-14
Atwood B.K., Lopez J., Wager-Miller J., Mackie K., Straiker A.
Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis.
BMC Genomics 12:14.1-14.14(2011)

PubMed=22651808; DOI=10.1186/1742-2094-9-115
Stansley B., Post J., Hensley K.
A comparative review of cell culture systems for the study of microglial biology in Alzheimer's disease.
J. Neuroinflamm. 9:115.1-115.8(2012)

PubMed=26227174; DOI=10.1002/pmic.201400623
Woo J.-M., Han D.-H., Park J.-H., Kim S.-J., Kim Y.-S.
In-depth characterization of the secretome of mouse CNS cell lines by LC-MS/MS without prefractionation.
Proteomics 15:3617-3622(2015)

DOI=10.1007/s13273-019-00057-6
Mandal C., Yoon T., Park J.Y., Jung K.H., Chai Y.G.
Lipopolysaccharide-dependent transcriptional regulation of PU.1 in microglial cells.
Mol. Cell. Toxicol. 16:51-61(2020)

Cross-references
Cell line databases/resourcesMCCL; MCC:0000073
CLDB; cl7130
CCRID; 1101MOU-PUMC000063
CCRID; 4201MOU-CCTCC00311
Lonza; 118
Anatomy/cell type resourcesBTO; BTO:0003350
Cell line collections (Providers)BCRJ; 0356
CCTCC; GDC0311
CLS; 305156
ICLC; ATL03001
KCB; KCB 200770YJ
Chemistry resourcesChEMBL-Cells; CHEMBL3307704
ChEMBL-Targets; CHEMBL614781
PubChem_Cell_line; CVCL_0182
Encyclopedic resourcesWikidata; Q54798657

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