p815小鼠肥大细胞瘤细胞

价 格:¥1800

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-2053

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameP815
SynonymsP-815; P 815
AccessionBTCC-2053
Resource Identification InitiativeTo cite this cell line use: P815 (BTCC-2053)
CommentsPart of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Doubling time: ~18-22 hours (DSMZ=ACC-1).
Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Omics: SNP array analysis.
Misspelling: P825; Note=Occasionally.
Sequence variations
  • Mutation; MGI; MGI:96677; Kit; Simple; p.Asp818Tyr (c.2452G>T) (D814Y); Zygosity=Unspecified (PubMed=7513208; PubMed=10210327).
DiseaseMouse mast cell neoplasm (NCIt: C21632)
Species of originMus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
HierarchyChildren:



CVCL_A9JC (P815 Hsp65-IL-2)CVCL_4Z63 (P815 MB)CVCL_4269 (P815-1-1)
CVCL_F735 (P815-X2)CVCL_C0DF (P815.Trh4)
Sex of cellMale
CategoryCancer cell line
STR profileSource(s): PubMed=31220119

Markers:
Mouse STR 1-116,17
Mouse STR 1-214,17,18
Mouse STR 2-115
Mouse STR 3-213,14
Mouse STR 4-220.3
Mouse STR 5-513
Mouse STR 6-417,18
Mouse STR 6-712
Mouse STR 7-127
Mouse STR 8-116
Mouse STR 11-216,17,18
Mouse STR 12-117
Mouse STR 13-117,18
Mouse STR 15-320.3,21.3
Mouse STR 17-217
Mouse STR 18-317
Mouse STR 19-212
Mouse STR X-127

Run an STR similarity search on this cell line
Web pageshttps://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/p/cell-lines-detail-232.html
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/p/cell-lines-detail-233.html
Publications

PubMed=4208429; DOI=10.1038/249049a0
Ralph P., Nakoinz I.
Lipopolysaccharides inhibit lymphosarcoma cells of bone marrow orgin.
Nature 249:49-51(1974)

PubMed=1234049; DOI=10.1002/eji.1830050208
Kiessling R., Klein E., Wigzell H.
'Natural' killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype.
Eur. J. Immunol. 5:112-117(1975)

DOI=10.2220/biomedres.5.19
Yanagisawa M., Hasegawa H., Ichiyama A., Hosoda S., Nakamura W.
Comparison of serotonin-producing murine mastocytomas, P-815 and FMA3: determination of tryptophan hydroxylase, aromatic L-amino acid decarboxylase, and cellular concentration of tryptophan, 5- hydroxytryprophan, 5-hydroxytryptamine and 5-hydroxyindoleacetic acid.
Biomed. Res. 5:19-28(1984)

PubMed=3792703; DOI=10.1111/j.1432-0436.1986.tb00568.x
Leenen P.J.M., Jansen A.M.A.C., van Ewijk W.
Murine macrophage cell lines can be ordered in a linear differentiation sequence.
Differentiation 32:157-164(1986)

PubMed=7513208; DOI=10.1182/blood.V83.9.2619.2619
Tsujimura T., Furitsu T., Morimoto M., Isozaki K., Nomura S., Matsuzawa Y., Kitamura Y., Kanakura Y.
Ligand-independent activation of c-kit receptor tyrosine kinase in a murine mastocytoma cell line P-815 generated by a point mutation.
Blood 83:2619-2626(1994)

PubMed=10210327; DOI=10.1016/S0301-472X(98)00075-7
London C.A., Galli S.J., Yuuki T., Hu Z.-Q., Helfand S.C., Geissler E.N.
Spontaneous canine mast cell tumors express tandem duplications in the proto-oncogene c-kit.
Exp. Hematol. 27:689-697(1999)

PubMed=18432777; DOI=10.1002/0471142735.im2004s43
Gajewski T.F., Markiewicz M.A., Uyttenhove C.
The P815 mastocytoma tumor model.
Curr. Protoc. Immunol. 43:20.4.1-20.4.18(2001)

PubMed=25277546; DOI=10.1186/1471-2164-15-847
Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W., Morse H.C. III, Pardo-Manuel de Villena F.
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.
BMC Genomics 15:847.1-847.11(2014)

PubMed=31220119; DOI=10.1371/journal.pone.0218412
Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B., Gollin S.M., Lewis D.W., Reid Y.A.
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:E0218412-E0218412(2019)

Cross-references
Cell line databases/resourcesCLO; CLO_0008340
CLO; CLO_0008341
CLO; CLO_0050217
CLDB; cl3784
CLDB; cl3785
CLDB; cl5244
CCRID; 1101MOU-PUMC000114
CCRID; 3101MOUSCSP516
CCRID; 3101MOUTCM12
CCRID; 4201MOU-CCTCC00608
DSMZCellDive; ACC-1
Lonza; 187
Anatomy/cell type resourcesBTO; BTO:0000985
Biological sample resourcesBioSample; SAMN11397663
Cell line collections (Providers)ATCC; TIB-64
BCRC; 60178
BCRJ; 0200
CCTCC; GDC0608
CLS; 400242
DSMZ; ACC-1
IZSLER; BS TCL 118
JCRB; IFO50029 - Discontinued
JCRB; JCRB0078
KCB; KCB 93032YJ
NCBI_Iran; C550
RCB; RCB1167
TKG; TKG 0168
Chemistry resourcesChEMBL-Cells; CHEMBL3307568
ChEMBL-Targets; CHEMBL614226
PubChem_Cell_line; CVCL_2154
Encyclopedic resourcesWikidata; Q54937317

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