HL-1 小鼠心肌细胞-BTCC典型培养物保藏中心-【BTCC细胞库】北京博沃尔斯生物科技有限公司官网

Cross-references
Cell line name	HL-1
Synonyms	HL1; HL-1 F2 P76
Accession	BTCC-2074
Resource Identification Initiative	To cite this cell line use: HL-1 (BTCC-2074)
Comments	Group: Patented cell line. Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12197. Characteristics: From transgenic mice expressing a fusion gene comprised of the atrial natriuretic factor promoter and the SV40 early region. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Heart, left atrium; UBERON=UBERON_0002079. Cell type: Cardiomyocyte; CL=CL_0002495.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C3HeB/FeJ transgenic.
Originate from same individual	CVCL_JK52 ! AT-1 [Mouse cardiomyocyte]
Sex of cell	Female
Category	Transformed cell line
Web pages	https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-549.html
Publications	PubMed=9501201; DOI=10.1073/pnas.95.6.2979 Claycomb W.C., Lanson N.A. Jr., Stallworth B.S., Egeland D.B., Delcarpio J.B., Bahinski A., Izzo N.J. Jr. HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte. Proc. Natl. Acad. Sci. U.S.A. 95:2979-2984(1998) PubMed=10908350; DOI=10.1093/nar/28.15.2882 Lanson N.A. Jr., Egeland D.B., Royals B.A., Claycomb W.C. The MRE11-NBS1-RAD50 pathway is perturbed in SV40 large T antigen-immortalized AT-1, AT-2 and HL-1 cardiomyocytes. Nucleic Acids Res. 28:2882-2892(2000) Patent=US6316207 Claycomb W.C. Mouse cardiac muscle cell line, HL-1. Patent number US6316207, 13-Nov-2001 PubMed=14766671; DOI=10.1152/ajpheart.00986.2003 White S.M., Constantin P.E., Claycomb W.C. Cardiac physiology at the cellular level: use of cultured HL-1 cardiomyocytes for studies of cardiac muscle cell structure and function. Am. J. Physiol. Heart Circ. Physiol. 286:H823-H829(2004)
Cell line databases/resources	MCCL; MCC:0000194 Lonza; 740
Anatomy/cell type resources	BTO; BTO:0003264
Cell line collections (Providers)	Millipore; SCC065
Encyclopedic resources	Wikidata; Q29838237

HL-1 小鼠心肌细胞

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