A20小鼠B细胞淋巴瘤-BTCC典型培养物保藏中心-【BTCC细胞库】北京博沃尔斯生物科技有限公司官网

Cell line name

A20

Synonyms

A-20

Accession

BTCC-2075

Resource Identification Initiative

To cite this cell line use: A20 (BTCC-2075)

Comments

Part of: ENCODE project mouse cell lines.
Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Doubling time: 18 hours (PubMed=310843).
Omics: Array-based CGH.

Disease

Mouse reticulum cell sarcoma (NCIt: C134780)

Species of origin

Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/cAnN.

Hierarchy

Children:


CVCL_YU22 (A20 NF-kappaB)	CVCL_QZ66 (A20-Fluc-Puro)	CVCL_C0MY (A20-Nluc-copGFP)
CVCL_D138 (A20/2J)

Sex of cell

Sex unspecified

Age at sampling

>15M

Category

Cancer cell line

STR profile

Source(s): PubMed=31220119

Markers:

Mouse STR 1-1	15,16
Mouse STR 1-2	17,18
Mouse STR 2-1	15
Mouse STR 3-2	13,14
Mouse STR 4-2	21.3
Mouse STR 5-5	14,15
Mouse STR 6-4	18
Mouse STR 6-7	11,12
Mouse STR 7-1	25.2
Mouse STR 8-1	12,13
Mouse STR 11-2	17
Mouse STR 12-1	16
Mouse STR 13-1	16.2,17.2
Mouse STR 15-3	22.3
Mouse STR 17-2	16,17
Mouse STR 18-3	15,16,18
Mouse STR 19-2	14
Mouse STR X-1	25

Web pages

https://en.wikipedia.org/wiki/A20_cells
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/a/cell-lines-detail-448.html
http://genome.ucsc.edu/ENCODE/protocols/cell/mouse/A20_Stam_protocol.pdf

Publications

PubMed=310843; DOI=10.4049/jimmunol.122.2.549
Kim K.J., Kanellopoulos-Langevin C., Merwin R.M., Sachs D.H., Asofsky R.
Establishment and characterization of BALB/c lymphoma lines with B cell properties.
J. Immunol. 122:549-554(1979)

PubMed=22400032; DOI=10.1155/2012/701704
Donnou S., Galand C., Touitou V., Sautes-Fridman C., Fabry Z., Fisson S.
Murine models of B-cell lymphomas: promising tools for designing cancer therapies.
Adv. Hematol. 2012:701704.1-701704.13(2012)

PubMed=28902524; DOI=10.1369/0022155417731319
Guja K., Liehr T., Rincic M., Kosyakova N., Hussein Azawi S.S.
Molecular cytogenetic characterization identified the murine B-cell lymphoma cell Line A-20 as a model for sporadic Burkitt's lymphoma.
J. Histochem. Cytochem. 65:669-677(2017)

PubMed=31220119; DOI=10.1371/journal.pone.0218412
Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B., Gollin S.M., Lewis D.W., Reid Y.A.
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:E0218412-E0218412(2019)

Cross-references

Cell line databases/resources

CLO; CLO_0001564
CLO; CLO_0050194
Lonza; 743
TOKU-E; 459

Anatomy/cell type resources

BTO; BTO:0001930

Biological sample resources

BioSample; SAMN11397658
ENCODE; ENCBS119ENC
ENCODE; ENCBS431JNZ

Cell line collections (Providers)

ATCC; TIB-208
BCRC; 60556
BCRJ; 0030
RCB; RCB2745
TKG; TKG 0571

Chemistry resources

ChEMBL-Cells; CHEMBL3307765
ChEMBL-Targets; CHEMBL613850
PubChem_Cell_line; CVCL_1940

Encyclopedic resources