L1210小鼠白血病细胞 -BTCC典型培养物保藏中心-【BTCC细胞库】北京博沃尔斯生物科技有限公司官网

Cell line name

L1210

Synonyms

L 1210; L-1210; Leukemic 1210; Leukemia 1210; Leukemia L1210

Accession

BTCC-2081

Resource Identification Initiative

To cite this cell line use: L1210 (BTCC-2081)

Comments

Part of: ENCODE project mouse cell lines.
Doubling time: 10-12 hours (CLS=400257); ~50 hours (DSMZ=ACC-123).
Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Omics: SNP array analysis.
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.

Disease

Mouse leukemia (NCIt: C21604)

Species of origin

Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.

Hierarchy

Children:


CVCL_IM26 (L1210 HHT)	CVCL_F929 (L1210 TGR3)	CVCL_C511 (L1210 TGR4)
CVCL_C513 (L1210-5FU-R-TC)	CVCL_H699 (L1210-6MP-R-TC)	CVCL_Y418 (L1210/0)
CVCL_R996 (L1210/Ara-C)	CVCL_4Y57 (L1210/CPA)	CVCL_1B40 (L1210/DDP)
CVCL_Y421 (L1210/DDP2)	CVCL_Y422 (L1210/DDP5)	CVCL_4V14 (L1210/PtR4)
CVCL_N029 (L1210/R71)	CVCL_N028 (L1210/R81)	CVCL_Y423 (L1210/TGO)
CVCL_4Y62 (L1210/TZR)	CVCL_Y424 (L1210:RD1694)	CVCL_B7N4 (MTA-13)

Sex of cell

Female

Age at sampling

Category

Cancer cell line

STR profile

Source(s): PubMed=31220119

Markers:

Mouse STR 1-1	15,17
Mouse STR 1-2	16
Mouse STR 2-1	15
Mouse STR 3-2	13
Mouse STR 4-2	20.3
Mouse STR 5-5	13
Mouse STR 6-4	17
Mouse STR 6-7	12
Mouse STR 7-1	27,28
Mouse STR 8-1	16
Mouse STR 11-2	17
Mouse STR 12-1	16
Mouse STR 13-1	17
Mouse STR 15-3	21.3,22.3
Mouse STR 17-2	16
Mouse STR 18-3	16,17
Mouse STR 19-2	12
Mouse STR X-1	27

Web pages

https://en.wikipedia.org/wiki/L1210_cells
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/l/cell-lines-detail-479.html

Publications

PubMed=18630317; DOI=10.1093/jnci/36.3.405
Moore G.E., Sandberg A.A., Ulrich K.
Suspension cell culture and in vivo and in vitro chromosome constitution of mouse leukemia L1210.
J. Natl. Cancer Inst. 36:405-413(1966)

PubMed=6970130; DOI=10.1002/eji.1830101111
Conzelmann A., Pink R., Acuto O., Mach J.-P., Dolivo S., Nabholz M.
Presence of T 145 on cytolytic T cell lines and their lectin-resistant mutants.
Eur. J. Immunol. 10:860-868(1980)

PubMed=6182115; DOI=10.1002/ijc.2910300317
Momparler R.L., Momparler L.F., Samson J.
Combinational chemotherapy of L1210 and L1210/ARA-C leukemia with 5-AZA-2'-deoxycytidine and beta-2'-deoxythioguanosine.
Int. J. Cancer 30:361-364(1982)

PubMed=25277546; DOI=10.1186/1471-2164-15-847
Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W., Morse H.C. III, Pardo-Manuel de Villena F.
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.
BMC Genomics 15:847.1-847.11(2014)

PubMed=31220119; DOI=10.1371/journal.pone.0218412
Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B., Gollin S.M., Lewis D.W., Reid Y.A.
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:E0218412-E0218412(2019)

Cross-references

Cell line databases/resources