CHO-K1中国仓鼠卵巢细胞

价 格:¥1800

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-4003

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameCHO-K1
SynonymsCHO K1; CHOK1; CHO cell clone K1; GM15452
AccessionBTCC-4003
Resource Identification InitiativeTo cite this cell line use: CHO-K1 (BTCC-4003)
CommentsRegistration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-9618.
Doubling time: ~24 hours (DSMZ=ACC-110).
Omics: Genome sequenced.
Omics: Metabolome analysis.
Omics: miRNA expression profiling.
Omics: Deep proteome analysis.
Omics: Glycoproteome analysis by proteomics.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Species of originCricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Sex of cellFemale
Age at samplingAdult
CategorySpontaneously immortalized cell line
Web pageshttps://en.wikipedia.org/wiki/Chinese_hamster_ovary_cell
https://www.chogenome.org/
http://genome.ucsc.edu/cgi-bin/hgGateway?db=criGriChoV2&redirect=manual&source=genome.ucsc.edu
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-30.html
https://web.archive.org/web/20160506232703/https://www.biotechhistory.org/magazine-article/vital-tools-brief-history-cho-cells/
https://www.phe-culturecollections.org.uk/media/128263/chok1-cell-line-profile.pdf
Publications

PubMed=10320750; DOI=10.1016/S0027-5107(99)00077-9
Hu T., Miller C.M., Ridder G.M., Aardema M.J.
Characterization of p53 in Chinese hamster cell lines CHO-K1, CHO-WBL, and CHL: implications for genotoxicity testing.
Mutat. Res. 426:51-62(1999)

PubMed=21804562; DOI=10.1038/nbt.1932
Xu X., Nagarajan H., Lewis N.E., Pan S.-K., Cai Z.-M., Liu X., Chen W.-B., Xie M., Wang W.-L., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W., Fan H.C., Wang J.-B., Gui Y.-T., Lee K.H., Betenbaugh M.J., Quake S.R., Famili I., Palsson B.O., Wang J.
The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.
Nat. Biotechnol. 29:735-741(2011)

PubMed=21945585; DOI=10.1016/j.jbiotec.2011.09.014
Becker J., Hackl M., Rupp O., Jakobi T., Schneider J., Szczepanowski R., Bekel T., Borth N., Goesmann A., Grillari J., Kaltschmidt C., Noll T., Puhler A., Tauch A., Brinkrolf K.
Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing.
J. Biotechnol. 156:227-235(2011)

PubMed=22971049; DOI=10.1021/pr300476w
Baycin-Hizal D., Tabb D.L., Chaerkady R., Chen L., Lewis N.E., Nagarajan H., Sarkaria V., Kumar A., Wolozny D., Colao J., Jacobson E., Tian Y., O'Meally R.N., Krag S.S., Cole R.N., Palsson B.O., Zhang H., Betenbaugh M.
Proteomic analysis of Chinese hamster ovary cells.
J. Proteome Res. 11:5265-5276(2012)

DOI=10.3390/pr1030296
Wurm F.M.
CHO quasispecies -- implications for manufacturing processes.
Processes 1:296-311(2013)

PubMed=23873082; DOI=10.1038/nbt.2624
Lewis N.E., Liu X., Li Y.-X., Nagarajan H., Yerganian G., O'Brien E., Bordbar A., Roth A.M., Rosenbloom J., Bian C., Xie M., Chen W.-B., Li N., Baycin-Hizal D., Latif H., Forster J., Betenbaugh M.J., Famili I., Xu X., Wang J., Palsson B.O.
Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome.
Nat. Biotechnol. 31:759-765(2013)

PubMed=26993211; DOI=10.1016/j.jbiotec.2016.03.022
Klanert G., Jadhav V., Shanmukam V., Diendorfer A.B., Karbiener M., Scheideler M., Hernandez-Bort J.A., Grillari J., Hackl M., Borth N.
A signature of 12 microRNAs is robustly associated with growth rate in a variety of CHO cell lines.
J. Biotechnol. 235:150-161(2016)

DOI=10.3390/pr5020020
Wurm F.M., Wurm M.J.
Cloning of CHO cells, productivity and genetic stability -- a discussion.
Processes 5:20.1-20.13(2017)

PubMed=28544881; DOI=10.1016/j.cels.2017.04.009
Yusufi F.N.K., Lakshmanan M., Ho Y.-S., Loo B.L.-W., Ariyaratne P., Yang Y., Ng S.-K., Tan T.R.-M., Yeo H.C., Lim H.L., Ng S.-W., Hiu A.-P., Chow C.-P., Wan C., Chen S., Teo G., Song G., Chin J.X., Ruan X., Sung K.W.-K., Hu W.-S., Yap M.G.-S., Bardor M., Nagarajan N., Lee D.-Y.
Mammalian systems biotechnology reveals global cellular adaptations in a recombinant CHO cell line.
Cell Syst. 4:530-542.e6(2017)

PubMed=32078082; DOI=10.1007/s10529-020-02841-0
Capella Roca B., Doolan P., Barron N., O'Neill F., Clynes M.
Altered gene expression in CHO cells following polyamine starvation.
Biotechnol. Lett. 42:927-936(2020)

PubMed=32619503; DOI=10.1016/j.ymben.2020.06.002
Szeliova D., Ruckerbauer D.E., Galleguillos S.N., Petersen L.B., Natter K., Hanscho M., Troyer C., Causon T., Schoeny H., Christensen H.B., Lee D.-Y., Lewis N.E., Koellensperger G., Hann S., Nielsen L.K., Borth N., Zanghellini J.
What CHO is made of: variations in the biomass composition of Chinese hamster ovary cell lines.
Metab. Eng. 61:288-300(2020)

PubMed=34050613; DOI=10.1002/biot.202100165
Wurm M.J., Wurm F.M.
Naming CHO cells for bio-manufacturing: genome plasticity and variant phenotypes of cell populations in bioreactors question the relevance of old names.
Biotechnol. J. 16:e2100165.1-e2100165.13(2021)

PubMed=34737324; DOI=10.1038/s41598-021-00779-5
Lung O., Candlish R.C., Nebroski M., Kruckiewicz P., Buchanan C., Moniwa M.
High-throughput sequencing for species authentication and contamination detection of 63 cell lines.
Sci. Rep. 11:21657-21657(2021)

PubMed=36610518; DOI=10.1016/j.ymben.2022.12.009
Kotidis P., Donini R., Arnsdorf J., Hansen A.H., Voldborg B.G.R., Chiang A.W.T., Haslam S.M., Betenbaugh M.J., Jimenez Del Val I., Lewis N.E., Krambeck F., Kontoravdi C.
CHOGlycoNET: comprehensive glycosylation reaction network for CHO cells.
Metab. Eng. 76:87-96(2023)

Cross-references
Cell line databases/resourcesCLO; CLO_0002427
CLO; CLO_0002462
CLO; CLO_0002463
CLO; CLO_0026669
CLO; CLO_0050409
CLO; CLO_0050420
CLO; CLO_0050423
MCCL; MCC:0000103
CLDB; cl730
CLDB; cl731
CLDB; cl732
CLDB; cl734
CLDB; cl735
CLDB; cl738
CLDB; cl739
CLDB; cl740
CLDB; cl741
CLDB; cl4897
CCRID; 1101HAM-PUMC000004
CCRID; 1102HAM-NIFDC00006
CCRID; 3101HAMGNHa7
CCRID; 3101HAMSCSP507
CCRID; 4201HAM-CCTCC00018
CCRID; 4201PAT-CCTCC00006
CCRID; 5301HAM-KCB88028YJ
CCRID; 6101MOU-CERC000111
DSMZCellDive; ACC-110
Lonza; 44
TOKU-E; 949
TOKU-E; 950
Anatomy/cell type resourcesBTO; BTO:0000457
Cell line collections (Providers)AddexBio; P0017001/33
ATCC; CCL-61
ATCC; CRL-9618
BCRC; 60006
BCRJ; 0069
CCLV; CCLV-RIE 0134
CCLV; CCLV-RIE 0315
CCTCC; GDC0018
CLS; 603480
Coriell; GM15452
DSMZ; ACC-110
ECACC; 85051005
IBRC; C10136
ICLC; ATL98003
IZSLER; BS CL 15
JCRB; IFO50414
JCRB; JCRB9018
KCB; KCB 88028YJ
KCLB; 10061
NCBI_Iran; C645
RCB; RCB0285
RCB; RCB2330
RCB; RCB2869
TKG; TKG 0328
Chemistry resourcesChEMBL-Cells; CHEMBL3307512
ChEMBL-Targets; CHEMBL614031
PubChem_Cell_line; CVCL_0214
Encyclopedic resourcesWikidata; Q54812705

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