Cell line name | Vero | ||||||||||||||||||||||||||||||||||||||||||
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Synonyms | VERO; VeroCCL81; Vero 81; Vero-81; Verda reno | ||||||||||||||||||||||||||||||||||||||||||
Accession | BTCC-4008 | ||||||||||||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: Vero (BTCC-4008) | ||||||||||||||||||||||||||||||||||||||||||
Comments | Group: Non-human primate cell line. Group: Vaccine production cell line. Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982). Biotechnology: Used for the production of the Japanese encephalitis virus (JEV) vaccine (Trade name: IXIARO/JESPECT). Biotechnology: Used for the production of the inactivated poliovirus vaccine (Trade name: Imovax Polio). Biotechnology: Used for the production of the Purified Vero-cell Rabies Vaccine (PVRV) (Trade name: VERORAB). Biotechnology: Used for the production of the Chromatographically Purified Rabies Vaccine (CPRV). Biotechnology: Used for the production of the live oral rotavirus vaccine (Trade Name: Rotarix). Biotechnology: Used for the production of the live smallpox (Vaccinia) vaccine (Trade name: ACAM2000). Biotechnology: Used for the production of the tetravalent dengue vaccine (Trade Name: Dengvaxia). Biotechnology: Used for the production of the Bharat Biotech SARS-CoV-2 (COVID-19) vaccine (Trade name: Covaxin; also known as BBV152) (DrugBank; DB15847). The cell line is used to produces a inactivated SARS-CoV-2 virus strain. Biotechnology: Used for the production of the Sinovax SARS-CoV-2 (COVID-19) vaccine (Trade name: CoronaVac; also known as PiCoVacc) (DrugBank; DB15806). The cell line is used to produces the inactivated SARS-CoV-2 virus strain CN02 (PubMed=32376603). Virology: Susceptible to infection by SARS coronavirus (SARS-CoV) (PubMed=16494729). Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19). But Vero C1008 (often known as Vero E6) (Cellosaurus=CVCL_0574) seems to be more appropriate for amplification and quantification (PubMed=32511316; PubMed=33389257). Omics: Genome sequenced. Anecdotal: Verda reno means green kidney in Esperanto and Vero means truth also in Esperanto. Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819. | ||||||||||||||||||||||||||||||||||||||||||
Species of origin | Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) (NCBI Taxonomy: 60711) | ||||||||||||||||||||||||||||||||||||||||||
Hierarchy | Children:
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Sex of cell | Female | ||||||||||||||||||||||||||||||||||||||||||
Age at sampling | Adult | ||||||||||||||||||||||||||||||||||||||||||
Category | Spontaneously immortalized cell line | ||||||||||||||||||||||||||||||||||||||||||
Web pages | https://en.wikipedia.org/wiki/Vero_cell https://www.fda.gov/ohrms/dockets/ac/00/backgrd/3616b1a.pdf https://en.vircell.com/products/vero-cell-line/ https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/v/cell-lines-detail-60.html https://micro.magnet.fsu.edu/primer/techniques/fluorescence/gallery/cells/vero/verocells.html https://www.olympus-lifescience.com/de/microscope-resource/primer/techniques/fluorescence/gallery/cells/agmindex/ https://www.phe-culturecollections.org.uk/media/122249/vero-cell-line-profile.pdf https://www.niid.go.jp/niid/ja/chlamydia-pneumonia-m/818-biochem/5752-vero.html https://www.precisionvaccinations.com/vaccines/covaxin-covid-19-vaccine | ||||||||||||||||||||||||||||||||||||||||||
Publications | CLPUB00126 PubMed=6027511; DOI=10.3181/00379727-125-32029 DOI=10.1007/BF02618370 PubMed=6298990; DOI=10.1016/0378-1135(82)90056-6 PubMed=4043530 CLPUB00328 PubMed=2260226 PubMed=10403033; DOI=10.1006/biol.1998.0156 PubMed=10494966 PubMed=12667817; DOI=10.1016/S0042-6822(02)00064-8 PubMed=16494729; DOI=10.3201/eid1201.050496 DOI=10.12665/J63.Morgan PubMed=19016439; DOI=10.1002/9780471729259.mca04es11 PubMed=19768803; DOI=10.1002/btpr.279 PubMed=19941903; DOI=10.1016/j.jviromet.2009.11.022 PubMed=22059503; DOI=10.1186/1472-6750-11-102 PubMed=24975811; DOI=10.1016/j.vaccine.2014.06.045 PubMed=25267831; DOI=10.1093/dnares/dsu029 PubMed=25903999; DOI=10.1002/biot.201400388 PubMed=28386771; DOI=10.1007/s10616-017-0082-7 PubMed=32376603; DOI=10.1126/science.abc1932 PubMed=32511316; DOI=10.1101/2020.03.02.972935 PubMed=33389257; DOI=10.1007/s10096-020-04106-0 | ||||||||||||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0009524 CLO; CLO_0050515 MCCL; MCC:0000480 CLDB; cl4643 CLDB; cl4644 CLDB; cl4645 CLDB; cl4648 CLDB; cl4649 CLDB; cl4650 CLDB; cl4651 CLDB; cl5170 CCRID; 1101MON-PUMC000060 CCRID; 1102MON-NIFDC00001 CCRID; 3101MONGNO10 CCRID; 3101MONSCSP520 CCRID; 4201MON-CCTCC00029 CCRID; 5301MON-KCB92017YJ FCS-free; 29-11-31-2-4-4 FCS-free; 29-11-47-1-8-9 FCS-free; 29-11-249-1-3-3 FCS-free; 29-11-338-1-16-3 FCS-free; 29-11-420-1-16-12 FCS-free; 29-11-433-1-16-12 FCS-free; 29-11-566-1-17-2 FCS-free; 29-11-587-1-18-2 FCS-free; 165-11-307-1-16-6 Lonza; 173 TOKU-E; 3415 | ||||||||||||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0001444 | ||||||||||||||||||||||||||||||||||||||||||
Cell line collections (Providers) | AddexBio; P0014002/4920 ATCC; CCL-81 ATCC; CCL-81.4 ATCC; CRL-6318 - Discontinued BCRC; 60013 BCRJ; 0245 CCLV; CCLV-RIE 0015 CCLV; CCLV-RIE 0078 CCTCC; GDC0029 CLS; 605372 ECACC; 08011101 ECACC; 84113001 IBRC; C10001 ICLC; ATL95005 IZSLER; BS CL 86 JCRB; IFO50471 JCRB; JCRB0111 JCRB; JCRB9013 KCB; KCB 92017YJ KCLB; 10081 NCBI_Iran; C101 RCB; RCB0001 TKG; TKG 0280 | ||||||||||||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3307520 ChEMBL-Targets; CHEMBL391 PubChem_Cell_line; CVCL_0059 | ||||||||||||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q3066564 | ||||||||||||||||||||||||||||||||||||||||||
Medical resources | MeSH; D014709 | ||||||||||||||||||||||||||||||||||||||||||
Metabolomic databases | MetaboLights; MTBLS2840 |