Cell line name | IPEC-J2 | |||||||||
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Synonyms | IPECJ2; Intestinal Porcine Epithelial Cell line-J2 | |||||||||
Accession | BTCC-4025 | |||||||||
Resource Identification Initiative | To cite this cell line use: IPEC-J2 (BTCC-4025) | |||||||||
Comments | Characteristics: Undergoes a process of spontaneous differentiation that leads to the formation of a polarized monolayer with low or high transepithelial electrical resistance (TEER), depending on the type of serum added to the culture medium, within 1-2 weeks (PubMed=29787056). Virology: Susceptible to infection by porcine circovirus type 2 (PCV2) (PubMed=25407967). Doubling time: ~40-60 hours (DSMZ=ACC-701). Omics: Deep proteome analysis. Omics: Transcriptome analysis by microarray. Derived from site: In situ; Small intestine, jejunum; UBERON=UBERON_0002115. Cell type: Enterocyte; CL=CL_0000584. | |||||||||
Species of origin | Sus scrofa (Pig) (NCBI Taxonomy: 9823) | |||||||||
Hierarchy | Children:
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Sex of cell | Sex unspecified | |||||||||
Age at sampling | <1D | |||||||||
Category | Spontaneously immortalized cell line | |||||||||
Publications | DOI=10.1016/S0016-5085(89)80002-2 PubMed=16215741; DOI=10.1007/s00418-005-0067-z PubMed=21626283; DOI=10.1007/s10616-011-9362-9 PubMed=22074860; DOI=10.1016/j.vetmic.2011.10.017 PubMed=22193509; DOI=10.1007/s10616-011-9420-3 DOI=10.1155/2013/980651 PubMed=24260272; DOI=10.1371/journal.pone.0079643 PubMed=25407967; DOI=10.1186/s12985-014-0193-0 PubMed=26147118; DOI=10.1371/journal.pone.0132323 PubMed=29787056; DOI=10.1007/978-3-319-16104-4_12 PubMed=26651362; DOI=10.1021/acs.molpharmaceut.5b00874 PubMed=26975772; DOI=10.4014/jmb.1512.12075 PubMed=32708885; DOI=10.3390/pharmaceutics12070673 | |||||||||
Cross-references | ||||||||||
Cell line databases/resources | DSMZCellDive; ACC-701 | |||||||||
Anatomy/cell type resources | BTO; BTO:0006402 | |||||||||
Cell line collections (Providers) | DSMZ; ACC-701 IZSLER; BS CL 205 | |||||||||
Encyclopedic resources | Wikidata; Q54897969 | |||||||||
Gene expression databases | GEO; GSM1646398 GEO; GSM1646399 GEO; GSM1646400 |