CNE-2人鼻咽癌细胞

价 格:¥1800

期 货:现货(冻存管发2支)

保藏中心:BTCC

资源编号:BTCC-1041

产地:中国

套 餐:

T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

详细资料说明书下载质检报告(COA)

Cell line nameCNE-2
SynonymsCNE2
AccessionCVCL_6889
Resource Identification InitiativeTo cite this cell line use: CNE-2 (RRID:CVCL_6889)
CommentsProblematic cell line: Contaminated. On the basis of the STR profile (PubMed=18196576) it is identical to CNE-1 and seems to be a hybrid of HeLa and of cell line of unknown origin. Originally thought to originate from a 68 year old male patient with a nasopharyngeal carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00474.
Omics: Transcriptome analysis by RNAseq.
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
HierarchyParent: CVCL_0030 (HeLa)
Children:



CVCL_6890 (CNE-2Z)CVCL_B0U9 (S18)CVCL_B0UB (S26)
CategoryHybrid cell line
STR profileSource(s): PubMed=18196576

Markers:
AmelogeninX
CSF1PO10,11
D2S133817,23
D3S135815,18
D5S81811,12
D7S82010,12
D8S117912,17
D13S31710,12,13.3
D16S5399,10
D18S5113,16
D19S43313
D21S1127,30
FGA18,21
TH016,7,9
TPOX8,9,12
vWA14,16

Run an STR similarity search on this cell line
Web pageshttps://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

CLPUB00143
Zhang S.-H., Gao X.-C., Zeng Y.
Cytogenetic studies on an epithelial cell line derived from poorly differentiated nasopharyngeal carcinoma.
Yi Chuan Xue Bao 10:498-503(1983)

PubMed=6852976; DOI=10.1002/ijc.2910310509
Zhang S.-H., Gao X.-K., Zeng Y.
Cytogenetic studies on an epithelial cell line derived from poorly differentiated nasopharyngeal carcinoma.
Int. J. Cancer 31:587-590(1983)

PubMed=17062557; DOI=10.1158/0008-5472.CAN-06-2977
Qian C.-N., Berghuis B., Tsarfaty G., Bruch M., Kort E.J., Ditlev J., Tsarfaty I., Hudson E., Jackson D.G., Petillo D., Chen J.-D., Resau J.H., Teh B.T.
Preparing the 'soil': the primary tumor induces vasculature reorganization in the sentinel lymph node before the arrival of metastatic cancer cells.
Cancer Res. 66:10365-10376(2006)

PubMed=18196576; DOI=10.1002/ijc.23374
Chan S.Y.-Y., Choy K.-W., Tsao S.-W., Tao Q., Tang T., Chung G.T.-Y., Lo K.-W.
Authentication of nasopharyngeal carcinoma tumor lines.
Int. J. Cancer 122:2169-2171(2008)

PubMed=24991015; DOI=10.1128/JVI.01457-14
Strong M.J., Baddoo M., Nanbo A., Xu M., Puetter A., Lin Z.
Comprehensive RNA-seq analysis reveals contamination of multiple nasopharyngeal carcinoma cell lines with HeLa cell genomes.
J. Virol. 88:10696-10704(2014)

PubMed=25028967; DOI=10.1371/journal.pone.0100843
Liang Y.-Y., Chen M.-Y., Hua Y.-J., Chen S., Zheng L.-S., Cao X., Peng L.-X., Xie P., Huang B.-J., Sun R., Wang L., Xiang Y.-Q., Guo X., Qian C.-N.
Downregulation of Ras association domain family member 6 (RASSF6) underlies the treatment resistance of highly metastatic nasopharyngeal carcinoma cells.
PLoS ONE 9:E100843-E100843(2014)

CLPUB00484
Xu Z.-H., Sun W.-W., Hang J.-B., Gao B.-L., Hu J.-A.
RNA-seq identified a novel functional MET fusion in head and neck cancer 5-8F cell line.
Int. J. Clin. Exp. Pathol. 9:8308-8317(2016)

Cross-references
Anatomy/cell type resourcesBTO; BTO:0005250
Biological sample resourcesBioSample; SAMN06481109
Cell line collections (Providers)CCTCC; GDC0155
Chemistry resourcesChEMBL-Cells; CHEMBL4295476
ChEMBL-Targets; CHEMBL4296409
PubChem_Cell_line; CVCL_6889
Encyclopedic resourcesWikidata; Q54813874
Gene expression databasesGEO; GSM375846
Polymorphism and mutation databasesCosmic; 755505
Cosmic; 923774
Cosmic; 944910
Cosmic; 1017619
Cosmic; 1300999
Cosmic; 1322947
Cosmic; 2366880
Progenetix; CVCL_6889
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number23

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